STRINGSTRING
C19orf12 C19orf12 W5K3D5_ASTMX W5K3D5_ASTMX W5K3H0_ASTMX W5K3H0_ASTMX W5K457_ASTMX W5K457_ASTMX tgfb1 tgfb1 tmem165 tmem165 LOC103045948 LOC103045948 W5K912_ASTMX W5K912_ASTMX Mcu Mcu W5KBL7_ASTMX W5KBL7_ASTMX W5KBZ4_ASTMX W5KBZ4_ASTMX Bax Bax Atp2c1 Atp2c1 LOC103035354 LOC103035354 stim1 stim1 gcm2 gcm2 W5KH13_ASTMX W5KH13_ASTMX LOC103021708 LOC103021708 LOC103047816 LOC103047816 LOC103022174 LOC103022174 LOC103045092 LOC103045092 W5KMZ7_ASTMX W5KMZ7_ASTMX LOC103045095 LOC103045095 adcy8 adcy8 LOC103024607 LOC103024607 W5KRB2_ASTMX W5KRB2_ASTMX W5KRV2_ASTMX W5KRV2_ASTMX W5KSD8_ASTMX W5KSD8_ASTMX LOC103042391 LOC103042391 stim2 stim2 W5KV56_ASTMX W5KV56_ASTMX immt immt LOC103029712 LOC103029712 LOC103031589 LOC103031589 W5KXE0_ASTMX W5KXE0_ASTMX W5KXG7_ASTMX W5KXG7_ASTMX letm1 letm1 casr casr LOC111193136 LOC111193136 LOC103047839 LOC103047839 Wwox Wwox Atp2b1 Atp2b1 W5L5A8_ASTMX W5L5A8_ASTMX W5L5C2_ASTMX W5L5C2_ASTMX W5L6C2_ASTMX W5L6C2_ASTMX cav3 cav3 TRPC7 TRPC7 LOC103025180 LOC103025180 LOC103029051 LOC103029051 LOC103025138 LOC103025138 LOC103033342 LOC103033342 LOC103031500 LOC103031500 f2 f2 slc8a3 slc8a3 Cherp Cherp slc30a1 slc30a1 tmem203 tmem203 LOC103030072 LOC103030072 ENSAMXP00000027661 ENSAMXP00000027661 LOC103045762 LOC103045762 calb1 calb1 LOC103021660 LOC103021660 LOC103042214 LOC103042214 ENSAMXP00000030195 ENSAMXP00000030195 LOC103046529 LOC103046529 LOC103037124 LOC103037124 LOC111194732 LOC111194732 ATP13A3 ATP13A3 ENSAMXP00000030711 ENSAMXP00000030711 ENSAMXP00000030762 ENSAMXP00000030762 trpa1 trpa1 LOC103035292 LOC103035292 gprc6a gprc6a LOC107197257 LOC107197257 trpc3 trpc3 atp2b4 atp2b4 ENSAMXP00000032866 ENSAMXP00000032866 LOC103037270 LOC103037270 LOC103037509 LOC103037509 ENSAMXP00000033131 ENSAMXP00000033131 stoml2 stoml2 ENSAMXP00000033496 ENSAMXP00000033496 ENSAMXP00000033800 ENSAMXP00000033800 LOC103044392 LOC103044392 LOC103046272 LOC103046272 LOC103040533 LOC103040533 LOC103024029 LOC103024029 SLC35G1 SLC35G1 ENSAMXP00000035716 ENSAMXP00000035716 tmem64 tmem64 ENSAMXP00000036179 ENSAMXP00000036179 slc24a1 slc24a1 dhrs7c dhrs7c LOC103035222 LOC103035222 pacs2 pacs2 LOC103023460 LOC103023460 SLC24A2 SLC24A2 LOC111192971 LOC111192971 LOC103028516 LOC103028516 LOC103045170 LOC103045170 rgn rgn LOC103040450 LOC103040450 Slc24a5 Slc24a5 stc1 stc1 LOC111190374 LOC111190374 LOC103043044 LOC103043044 nptn nptn atp13a2 atp13a2 tmem178a tmem178a LOC103044006 LOC103044006 anxa6 anxa6 LOC103038368 LOC103038368 LOC103039548 LOC103039548 LOC103039228 LOC103039228 LOC103044496 LOC103044496 ENSAMXP00000044622 ENSAMXP00000044622 LOC103021510 LOC103021510 LOC103024994 LOC103024994 LOC103030483 LOC103030483 slc24a3 slc24a3 LOC103031161 LOC103031161 LOC111197359 LOC111197359 LOC103038069 LOC103038069 trpc1 trpc1 ENSAMXP00000046048 ENSAMXP00000046048 ENSAMXP00000046829 ENSAMXP00000046829 LOC103044865 LOC103044865 letm2 letm2 ENSAMXP00000047619 ENSAMXP00000047619 ENSAMXP00000047894 ENSAMXP00000047894 LOC103040945 LOC103040945 atp2b3 atp2b3 LOC103030403 LOC103030403 ENSAMXP00000048278 ENSAMXP00000048278 RYR2 RYR2 C19orf12-2 C19orf12-2 LOC103039460 LOC103039460 PLN PLN ENSAMXP00000050411 ENSAMXP00000050411 ENSAMXP00000050759 ENSAMXP00000050759 LOC103038570 LOC103038570 LOC103034108 LOC103034108 LOC103033738 LOC103033738 scgn scgn ENSAMXP00000051577 ENSAMXP00000051577 micu1 micu1 LOC103023443 LOC103023443 atp13a1 atp13a1 tgfb2 tgfb2 LOC103035660 LOC103035660 ENSAMXP00000053261 ENSAMXP00000053261 smdt1 smdt1 slc8b1 slc8b1 ENSAMXP00000054671 ENSAMXP00000054671 Ryr1 Ryr1 atp2b2 atp2b2 W5JZ03_ASTMX W5JZ03_ASTMX W5JZK3_ASTMX W5JZK3_ASTMX hcrtr2 hcrtr2 W5K0V1_ASTMX W5K0V1_ASTMX Htr2b Htr2b BCL2 BCL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C19orf12Chromosome 19 open reading frame 12. (141 aa)
W5K3D5_ASTMXSolute carrier family 24 member 4a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (514 aa)
W5K3H0_ASTMXSolute carrier family 8 member 1b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (662 aa)
W5K457_ASTMXTransmembrane O-mannosyltransferase targeting cadherins 4. (616 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
tmem165GDT1 family protein. (303 aa)
LOC103045948Glutamate receptor, metabotropic 5b. (1213 aa)
W5K912_ASTMXWolfram syndrome 1a (wolframin). (542 aa)
McuMitochondrial calcium uniporter. (277 aa)
W5KBL7_ASTMXRyanodine receptor 3. (4703 aa)
W5KBZ4_ASTMX5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate b. (480 aa)
BaxBCL2 associated X, apoptosis regulator a. (190 aa)
Atp2c1ATPase secretory pathway Ca2+ transporting 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (894 aa)
LOC103035354Transient receptor potential cation channel subfamily C member 2b; Belongs to the transient receptor (TC 1.A.4) family. (1014 aa)
stim1Stromal interaction molecule 1b. (674 aa)
gcm2Glial cells missing transcription factor 2. (493 aa)
W5KH13_ASTMXMitochondrial calcium uptake 2. (383 aa)
LOC103021708Solute carrier family 8 member 4a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (939 aa)
LOC103047816Zgc:153993. (204 aa)
LOC103022174Transient receptor potential cation channel, subfamily A, member 1a; Belongs to the transient receptor (TC 1.A.4) family. (1097 aa)
LOC103045092Transient receptor potential cation channel, subfamily C, member 4b; Belongs to the transient receptor (TC 1.A.4) family. (916 aa)
W5KMZ7_ASTMXRyanodine receptor 1a (skeletal). (4937 aa)
LOC103045095Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1228 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
W5KRB2_ASTMXSi:ch211-39a7.1. (430 aa)
W5KRV2_ASTMXCadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (757 aa)
W5KSD8_ASTMXCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1033 aa)
LOC103042391MCU domain-containing protein. (330 aa)
stim2Stromal interaction molecule 2b. (708 aa)
W5KV56_ASTMXRyanodine receptor 2b (cardiac). (4690 aa)
immtMICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (769 aa)
LOC103029712Solute carrier family 8 member 1a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (991 aa)
LOC103031589Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1183 aa)
W5KXE0_ASTMXTransient receptor potential cation channel subfamily C member 2a. (801 aa)
W5KXG7_ASTMXCoiled-coil domain containing 47. (416 aa)
letm1Leucine zipper-EF-hand containing transmembrane protein 1. (758 aa)
casrCalcium-sensing receptor. (946 aa)
LOC111193136G_PROTEIN_RECEP_F3_4 domain-containing protein; Belongs to the G-protein coupled receptor 3 family. (824 aa)
LOC103047839Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (460 aa)
WwoxWW domain containing oxidoreductase. (383 aa)
Atp2b1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1222 aa)
W5L5A8_ASTMXCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1253 aa)
W5L5C2_ASTMXGlutamate receptor, metabotropic 1a. (1139 aa)
W5L6C2_ASTMXSelenoprotein K. (91 aa)
cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (150 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
LOC103025180Transient receptor potential cation channel, subfamily C, member 6a; Belongs to the transient receptor (TC 1.A.4) family. (888 aa)
LOC103029051Solute carrier family 8 member 4b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (920 aa)
LOC103025138Solute carrier family 37 member 4a. (429 aa)
LOC103033342Calbindin 2a. (271 aa)
LOC103031500Uncharacterized protein. (346 aa)
f2Coagulation factor II (thrombin); Belongs to the peptidase S1 family. (619 aa)
slc8a3Solute carrier family 8 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
CherpCalcium homeostasis endoplasmic reticulum protein. (987 aa)
slc30a1Solute carrier family 30 member 1a. (518 aa)
tmem203Transmembrane protein 203. (136 aa)
LOC103030072G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (362 aa)
ENSAMXP000000276615-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. (221 aa)
LOC103045762Cation/H+ exchanger protein 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (757 aa)
calb1Calbindin 1. (290 aa)
LOC103021660Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1065 aa)
LOC103042214Endothelin 3b. (168 aa)
ENSAMXP00000030195Uncharacterized protein. (261 aa)
LOC103046529Solute carrier family 8 member 2a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
LOC103037124Uncharacterized protein. (277 aa)
LOC111194732Uncharacterized protein. (614 aa)
ATP13A3Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (735 aa)
ENSAMXP00000030711G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (179 aa)
ENSAMXP00000030762Stromal interaction molecule 1a. (751 aa)
trpa1Transient receptor potential cation channel, subfamily A, member 1b; Belongs to the transient receptor (TC 1.A.4) family. (1106 aa)
LOC103035292Transient receptor potential cation channel, subfamily C, member 7a; Belongs to the transient receptor (TC 1.A.4) family. (905 aa)
gprc6aG protein-coupled receptor, class C, group 6, member A. (893 aa)
LOC107197257Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (451 aa)
trpc3Transient receptor potential cation channel, subfamily C, member 3; Belongs to the transient receptor (TC 1.A.4) family. (918 aa)
atp2b4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1200 aa)
ENSAMXP00000032866Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1148 aa)
LOC103037270Solute carrier family 37 member 4b. (453 aa)
LOC103037509Solute carrier family 30 member 1b. (485 aa)
ENSAMXP00000033131G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (475 aa)
stoml2Stomatin (EPB72)-like 2. (362 aa)
ENSAMXP00000033496Cysteine and glycine-rich protein 3 (cardiac LIM protein). (182 aa)
ENSAMXP00000033800Uncharacterized protein. (309 aa)
LOC103044392Uncharacterized protein. (300 aa)
LOC103046272Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (602 aa)
LOC103040533Glutamate receptor, metabotropic 5a. (1187 aa)
LOC103024029Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1005 aa)
SLC35G1Solute carrier family 35 member G1. (248 aa)
ENSAMXP00000035716Uncharacterized protein. (260 aa)
tmem64Transmembrane protein 64. (345 aa)
ENSAMXP00000036179Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (211 aa)
slc24a1Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (762 aa)
dhrs7cDehydrogenase/reductase (SDR family) member 7Cb. (314 aa)
LOC103035222Transient receptor potential cation channel, subfamily C, member 4a; Belongs to the transient receptor (TC 1.A.4) family. (924 aa)
pacs2Phosphofurin acidic cluster sorting protein 2. (954 aa)
LOC103023460Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
SLC24A2Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (619 aa)
LOC111192971Dehydrogenase/reductase (SDR family) member 7Ca. (321 aa)
LOC103028516Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (605 aa)
LOC103045170Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1005 aa)
rgnRegucalcin. (299 aa)
LOC103040450Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1041 aa)
Slc24a5Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (112 aa)
stc1Stanniocalcin 1. (250 aa)
LOC111190374Uncharacterized protein. (256 aa)
LOC103043044Solute carrier family 24 member 4b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (653 aa)
nptnNeuroplastin b. (398 aa)
atp13a2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1170 aa)
tmem178aTransmembrane protein 178. (306 aa)
LOC103044006Transient receptor potential cation channel, subfamily C, member 5a; Belongs to the transient receptor (TC 1.A.4) family. (1029 aa)
anxa6Annexin. (667 aa)
LOC103038368Uncharacterized protein. (140 aa)
LOC103039548BCL2 apoptosis regulator. (218 aa)
LOC103039228Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (993 aa)
LOC103044496Cation/H+ exchanger protein 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (767 aa)
ENSAMXP00000044622Ins145_P3_rec domain-containing protein. (117 aa)
LOC103021510Neuroplastin a. (404 aa)
LOC103024994Stanniocalcin 2a. (275 aa)
LOC103030483Cholinergic receptor, nicotinic, alpha 7 (neuronal). (506 aa)
slc24a3Solute carrier family 24 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (634 aa)
LOC103031161Tromal interaction molecule 2a. (1019 aa)
LOC111197359Uncharacterized protein. (492 aa)
LOC103038069Wolfram syndrome 1b (wolframin). (908 aa)
trpc1Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family. (798 aa)
ENSAMXP00000046048Solute carrier family 24 member 6a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (559 aa)
ENSAMXP00000046829Transient receptor potential cation channel, subfamily C, member 6b; Belongs to the transient receptor (TC 1.A.4) family. (823 aa)
LOC103044865Si:ch211-270g19.5. (52 aa)
letm2Leucine zipper-EF-hand containing transmembrane protein 2. (475 aa)
ENSAMXP00000047619CD40 molecule, TNF receptor superfamily member 5. (353 aa)
ENSAMXP00000047894Endothelin 1. (162 aa)
LOC103040945Kell metallo-endopeptidase (Kell blood group). (769 aa)
atp2b3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1277 aa)
LOC103030403Mitochondrial calcium uptake family, member 3b. (480 aa)
ENSAMXP00000048278Solute carrier family 8 member 2b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (849 aa)
RYR2Uncharacterized protein. (4856 aa)
C19orf12-2Chromosome 19 open reading frame 12. (141 aa)
LOC103039460Uncharacterized protein. (346 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
ENSAMXP00000050411Transient receptor potential cation channel, subfamily C, member 5b; Belongs to the transient receptor (TC 1.A.4) family. (889 aa)
ENSAMXP00000050759B30.2/SPRY domain-containing protein. (303 aa)
LOC103038570Zgc:112052. (140 aa)
LOC103034108Calbindin 2b. (272 aa)
LOC103033738Uncharacterized protein. (490 aa)
scgnSecretagogin, EF-hand calcium binding protein. (272 aa)
ENSAMXP00000051577Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (399 aa)
micu1Mitochondrial calcium uptake 1. (487 aa)
LOC103023443Single-pass membrane protein with aspartate-rich tail 1b. (98 aa)
atp13a1Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1189 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
LOC103035660Zgc:110224. (437 aa)
ENSAMXP00000053261annotation not available (35 aa)
smdt1Single-pass membrane protein with aspartate-rich tail 1a. (107 aa)
slc8b1Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (590 aa)
ENSAMXP00000054671Uncharacterized protein. (208 aa)
Ryr1Ryanodine receptor 1b (skeletal). (4957 aa)
atp2b2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1273 aa)
W5JZ03_ASTMXGlutamate receptor, metabotropic 1b. (1159 aa)
W5JZK3_ASTMXSi:ch73-330k17.3. (229 aa)
hcrtr2Hypocretin (orexin) receptor 2. (426 aa)
W5K0V1_ASTMXSi:ch73-380n15.2. (530 aa)
Htr2b5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (467 aa)
BCL2BCL2 apoptosis regulator. (201 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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