STRINGSTRING
LOC103041996 LOC103041996 mib2 mib2 TMEM100-2 TMEM100-2 ift74 ift74 ENSAMXP00000054497 ENSAMXP00000054497 grip2 grip2 Fsd1 Fsd1 gmds gmds ENSAMXP00000053261 ENSAMXP00000053261 LOC103043594 LOC103043594 tgfb2 tgfb2 Cfap58 Cfap58 LOC103025197 LOC103025197 Sel1l Sel1l Dll3 Dll3 PLN PLN hey2 hey2 LOC103023492 LOC103023492 DTX1 DTX1 ENSAMXP00000047819 ENSAMXP00000047819 LOC103044865 LOC103044865 mecp2 mecp2 ENSAMXP00000046776 ENSAMXP00000046776 chac1 chac1 ENSAMXP00000046422 ENSAMXP00000046422 LOC103033594 LOC103033594 ENSAMXP00000045440 ENSAMXP00000045440 dlx6 dlx6 traf7 traf7 LOC103042559 LOC103042559 ENSAMXP00000043778 ENSAMXP00000043778 gsx1 gsx1 ENSAMXP00000043377 ENSAMXP00000043377 psenen psenen LOC103047857 LOC103047857 LOC103031228 LOC103031228 ENSAMXP00000041605 ENSAMXP00000041605 dtx3 dtx3 snai2 snai2 ENSAMXP00000039539 ENSAMXP00000039539 ENSAMXP00000039487 ENSAMXP00000039487 ENSAMXP00000039291 ENSAMXP00000039291 TMEM100 TMEM100 Itgb1bp1 Itgb1bp1 timp4 timp4 Mib1 Mib1 LOC103031245 LOC103031245 LOC103030559 LOC103030559 hey1 hey1 lfng lfng maml1 maml1 LOC103027213 LOC103027213 LOC103031354 LOC103031354 NRARP NRARP LOC103027184 LOC103027184 ENSAMXP00000032700 ENSAMXP00000032700 JAG1 JAG1 ENSAMXP00000031485 ENSAMXP00000031485 LOC103024849 LOC103024849 susd5 susd5 LOC103027782 LOC103027782 ENSAMXP00000030535 ENSAMXP00000030535 LOC103029087 LOC103029087 nle1 nle1 ENSAMXP00000029721 ENSAMXP00000029721 NCSTN NCSTN nrarp nrarp LOC103029720 LOC103029720 tgfbr2 tgfbr2 nr1h4 nr1h4 pkd2 pkd2 W5LD95_ASTMX W5LD95_ASTMX dll4 dll4 dll1 dll1 LOC103034623 LOC103034623 bap1 bap1 LOC103047839 LOC103047839 LOC103045468 LOC103045468 mettl3 mettl3 LOC103043423 LOC103043423 LOC103043413 LOC103043413 LOC103026639 LOC103026639 LOC103029567 LOC103029567 rbpj rbpj jag1 jag1 MAML2 MAML2 LOC103024607 LOC103024607 W5KLW4_ASTMX W5KLW4_ASTMX LOC103031030 LOC103031030 LOC103038960 LOC103038960 W5KGW2_ASTMX W5KGW2_ASTMX GALNT11 GALNT11 W5KF46_ASTMX W5KF46_ASTMX W5K8B8_ASTMX W5K8B8_ASTMX W5K581_ASTMX W5K581_ASTMX pofut1 pofut1 tgfb1 tgfb1 got1 got1 W5K0Q2_ASTMX W5K0Q2_ASTMX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103041996ADAM metallopeptidase domain 17b. (841 aa)
mib2Mindbomb E3 ubiquitin protein ligase 2. (1017 aa)
TMEM100-2Transmembrane protein 100. (147 aa)
ift74Intraflagellar transport 74. (599 aa)
ENSAMXP00000054497RING-type domain-containing protein. (539 aa)
grip2Glutamate receptor interacting protein 2b. (1124 aa)
Fsd1Fibronectin type III and SPRY domain containing 1. (546 aa)
gmdsGDP-mannose 4,6-dehydratase. (377 aa)
ENSAMXP00000053261annotation not available (35 aa)
LOC103043594Hairy-related 1. (307 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
Cfap58Uncharacterized protein. (92 aa)
LOC103025197Notch receptor 1b. (2477 aa)
Sel1lSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (819 aa)
Dll3Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (708 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
hey2Hes-related family bHLH transcription factor with YRPW motif 2. (315 aa)
LOC103023492Si:dkey-3h3.3. (439 aa)
DTX1Deltex E3 ubiquitin ligase 1. (635 aa)
ENSAMXP00000047819Beta-1,3-N-acetylglucosaminyltransferase. (356 aa)
LOC103044865Si:ch211-270g19.5. (52 aa)
mecp2Methyl CpG binding protein 2. (612 aa)
ENSAMXP00000046776DTC domain-containing protein. (217 aa)
chac1Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (206 aa)
ENSAMXP00000046422DTC domain-containing protein. (410 aa)
LOC103033594APH1B gamma secretase subunit. (258 aa)
ENSAMXP00000045440Uncharacterized protein. (183 aa)
dlx6Distal-less homeobox 6a. (247 aa)
traf7TNF receptor-associated factor 7. (688 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
ENSAMXP00000043778BHLH domain-containing protein. (198 aa)
gsx1Homeobox domain-containing protein. (273 aa)
ENSAMXP00000043377Glutamate receptor interacting protein 2a. (1001 aa)
psenenPresenilin enhancer, gamma-secretase subunit. (101 aa)
LOC103047857Glutamic-oxaloacetic transaminase 1 like 1. (410 aa)
LOC103031228Nuclear receptor interacting protein 2. (305 aa)
ENSAMXP00000041605Si:ch1073-396h14.1. (694 aa)
dtx3Zgc:66440. (372 aa)
snai2Snail family zinc finger 2. (259 aa)
ENSAMXP00000039539Hairy-related 1. (280 aa)
ENSAMXP00000039487Zgc:114200. (259 aa)
ENSAMXP00000039291RING-type domain-containing protein. (200 aa)
TMEM100Uncharacterized protein. (139 aa)
Itgb1bp1Integrin beta 1 binding protein 1. (184 aa)
timp4TIMP metallopeptidase inhibitor 4, tandem duplicate 3. (223 aa)
Mib1Mindbomb E3 ubiquitin protein ligase 1. (1027 aa)
LOC103031245Protein tyrosine phosphatase 4A3a. (173 aa)
LOC103030559Deltex 4, E3 ubiquitin ligase b. (733 aa)
hey1Hes-related family bHLH transcription factor with YRPW motif 1. (323 aa)
lfngLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (457 aa)
maml1Mastermind-like transcriptional coactivator 1. (1070 aa)
LOC103027213Hairy-related 2. (151 aa)
LOC103031354Hairy-related 5. (232 aa)
NRARPNOTCH regulated ankyrin repeat protein b. (107 aa)
LOC103027184ADAM metallopeptidase domain 10b. (792 aa)
ENSAMXP00000032700Uncharacterized protein. (159 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1239 aa)
ENSAMXP00000031485Si:ch73-78o10.1. (154 aa)
LOC103024849Hes related family bHLH transcription factor with YRPW motif like. (331 aa)
susd5Sushi domain containing 5. (715 aa)
LOC103027782Nuclear receptor subfamily 0, group B, member 2a. (257 aa)
ENSAMXP00000030535RING-type domain-containing protein. (203 aa)
LOC103029087Protein tyrosine phosphatase 4A3b. (173 aa)
nle1Notchless homolog 1 (Drosophila). (476 aa)
ENSAMXP00000029721Mastermind-like transcriptional coactivator 3. (1154 aa)
NCSTNNicastrin. (704 aa)
nrarpNOTCH regulated ankyrin repeat protein a. (112 aa)
LOC103029720Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1257 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
nr1h4Nuclear receptor subfamily 1, group H, member 4. (486 aa)
pkd2Polycystic kidney disease 2. (903 aa)
W5LD95_ASTMXADAM metallopeptidase domain 17a. (675 aa)
dll4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (695 aa)
dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (719 aa)
LOC103034623Notch receptor 1a. (2450 aa)
bap1Ubiquitin carboxyl-terminal hydrolase. (768 aa)
LOC103047839Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (460 aa)
LOC103045468Nuclear receptor subfamily 0, group B, member 2b. (267 aa)
mettl3Methyltransferase like 3; Belongs to the MT-A70-like family. (591 aa)
LOC103043423ADAM metallopeptidase domain 10a. (793 aa)
LOC103043413Nuclear receptor subfamily 1, group H, member 5. (495 aa)
LOC103026639Deltex 4, E3 ubiquitin ligase a. (706 aa)
LOC103029567Recombination signal binding protein for immunoglobulin kappa J region a. (502 aa)
rbpjRecombination signal binding protein for immunoglobulin kappa J region b. (494 aa)
jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1229 aa)
MAML2Mastermind like transcriptional coactivator 2. (870 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
W5KLW4_ASTMXUncharacterized protein. (1195 aa)
LOC103031030Hairy-related 11. (286 aa)
LOC103038960Deltex 2, E3 ubiquitin ligase. (657 aa)
W5KGW2_ASTMXDelta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (600 aa)
GALNT11Polypeptide N-acetylgalactosaminyltransferase. (593 aa)
W5KF46_ASTMXTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (561 aa)
W5K8B8_ASTMXThrombospondin-type laminin G domain and EAR repeats b. (446 aa)
W5K581_ASTMXPresenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (436 aa)
pofut1Protein O-fucosyltransferase 1. (396 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
got1Aspartate aminotransferase. (410 aa)
W5K0Q2_ASTMXDelta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (726 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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