STRINGSTRING
W5K3H2_ASTMX W5K3H2_ASTMX kiaa0586 kiaa0586 iqub iqub tmem231 tmem231 ro60 ro60 Gli3 Gli3 W5K4Q5_ASTMX W5K4Q5_ASTMX LOC103032733 LOC103032733 Rb1 Rb1 W5KF46_ASTMX W5KF46_ASTMX W5KIU0_ASTMX W5KIU0_ASTMX W5KJ68_ASTMX W5KJ68_ASTMX ptchd1 ptchd1 W5KQ23_ASTMX W5KQ23_ASTMX ptchd4 ptchd4 ttc21b ttc21b ssna1 ssna1 bbs7 bbs7 disp1 disp1 LOC103035832 LOC103035832 W5L312_ASTMX W5L312_ASTMX boc boc sufu sufu ift27 ift27 stil stil W5LK41_ASTMX W5LK41_ASTMX tgfbr2 tgfbr2 shh shh LOC103028990 LOC103028990 stk36 stk36 LOC103036215 LOC103036215 ulk3 ulk3 Wdr19 Wdr19 Gli1 Gli1 ENSAMXP00000032700 ENSAMXP00000032700 smo smo LOC103027213 LOC103027213 nsdhl nsdhl LOC103032897 LOC103032897 fkbp8 fkbp8 ENSAMXP00000036990 ENSAMXP00000036990 ENSAMXP00000037031 ENSAMXP00000037031 ENSAMXP00000037874 ENSAMXP00000037874 hspb11 hspb11 gli2 gli2 ift52 ift52 Wdpcp Wdpcp ttc26 ttc26 ENSAMXP00000043778 ENSAMXP00000043778 LOC103042559 LOC103042559 dhh dhh ENSAMXP00000045682 ENSAMXP00000045682 ENSAMXP00000046843 ENSAMXP00000046843 Rest Rest ptch1 ptch1 b9d1 b9d1 tmem17 tmem17 arl13b arl13b disp2 disp2 ENSAMXP00000054649 ENSAMXP00000054649 septin2 septin2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5K3H2_ASTMXHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (418 aa)
kiaa0586Si:ch211-185a18.2. (1626 aa)
iqubIQ motif and ubiquitin domain containing. (764 aa)
tmem231Transmembrane protein 231. (309 aa)
ro60Ro60, Y RNA binding protein. (542 aa)
Gli3GLI family zinc finger 3. (1434 aa)
W5K4Q5_ASTMXHedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family. (505 aa)
LOC103032733Zgc:77752. (621 aa)
Rb1Retinoblastoma 1. (882 aa)
W5KF46_ASTMXTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (561 aa)
W5KIU0_ASTMXMKS transition zone complex subunit 1. (528 aa)
W5KJ68_ASTMXPeptidylprolyl isomerase. (501 aa)
ptchd1Patched domain containing 1. (888 aa)
W5KQ23_ASTMXPatched 2. (1330 aa)
ptchd4Patched domain containing 4. (913 aa)
ttc21bTetratricopeptide repeat domain 21B. (1320 aa)
ssna1Sjogren syndrome nuclear autoantigen 1. (113 aa)
bbs7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
disp1Dispatched homolog 1 (Drosophila). (1522 aa)
LOC103035832Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (416 aa)
W5L312_ASTMXIntraflagellar transport 80 homolog (Chlamydomonas). (768 aa)
bocBOC cell adhesion associated, oncogene regulated. (1045 aa)
sufuSuppressor of fused homolog. (483 aa)
ift27Intraflagellar transport 27 homolog (Chlamydomonas). (186 aa)
stilSTIL centriolar assembly protein. (1303 aa)
W5LK41_ASTMXCell adhesion associated, oncogene regulated. (1109 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
shhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (429 aa)
LOC103028990GLI family zinc finger 2b. (1488 aa)
stk36Serine/threonine kinase 36 (fused homolog, Drosophila). (1329 aa)
LOC103036215Zgc:112294. (217 aa)
ulk3Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (472 aa)
Wdr19WD repeat domain 19. (1339 aa)
Gli1GLI family zinc finger 1. (1480 aa)
ENSAMXP00000032700Uncharacterized protein. (159 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (840 aa)
LOC103027213Hairy-related 2. (151 aa)
nsdhlNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (345 aa)
LOC103032897Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
fkbp8Peptidylprolyl isomerase. (389 aa)
ENSAMXP00000036990Hint domain-containing protein. (153 aa)
ENSAMXP00000037031MKS transition zone complex subunit 1. (534 aa)
ENSAMXP00000037874Zgc:63587; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (363 aa)
hspb11Zgc:158640. (171 aa)
gli2GLI family zinc finger 2a. (1447 aa)
ift52Intraflagellar transport 52 homolog (Chlamydomonas). (435 aa)
WdpcpUncharacterized protein. (98 aa)
ttc26Tetratricopeptide repeat domain 26. (557 aa)
ENSAMXP00000043778BHLH domain-containing protein. (198 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
dhhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (445 aa)
ENSAMXP00000045682Cilia and flagella associated protein 410. (241 aa)
ENSAMXP00000046843Uncharacterized protein. (683 aa)
RestRE1-silencing transcription factor. (1235 aa)
ptch1Patched 1. (1506 aa)
b9d1B9 protein domain 1. (205 aa)
tmem17Transmembrane protein 17. (191 aa)
arl13bADP-ribosylation factor-like 13b. (410 aa)
disp2Dispatched homolog 2 (Drosophila). (1479 aa)
ENSAMXP00000054649Signal peptide, CUB domain, EGF-like 2. (976 aa)
septin2Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (370 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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