STRINGSTRING
LOC103032545 LOC103032545 fgf16 fgf16 ENSAMXP00000054408 ENSAMXP00000054408 plpp3 plpp3 ENSAMXP00000053597 ENSAMXP00000053597 LOC103042476 LOC103042476 sp1 sp1 sash1 sash1 ENSAMXP00000050058 ENSAMXP00000050058 LOC103027828 LOC103027828 rab25 rab25 LOC103041475 LOC103041475 LOC103046764 LOC103046764 LOC103042520 LOC103042520 LOC103029481 LOC103029481 LOC103029863 LOC103029863 LOC103047026 LOC103047026 ENSAMXP00000047619 ENSAMXP00000047619 glipr2 glipr2 ENSAMXP00000046398 ENSAMXP00000046398 ENSAMXP00000046336 ENSAMXP00000046336 TSTA3-2 TSTA3-2 gpi gpi LOC103029654 LOC103029654 LOC103042559 LOC103042559 LOC103038135 LOC103038135 TSTA3 TSTA3 cib1 cib1 fgf7 fgf7 LOC103040845 LOC103040845 Itgb1bp1 Itgb1bp1 fgf2 fgf2 ENSAMXP00000036546 ENSAMXP00000036546 capn7 capn7 LOC103041352 LOC103041352 LOC103029333 LOC103029333 LOC103025626 LOC103025626 LOC103032641 LOC103032641 ENSAMXP00000034094 ENSAMXP00000034094 ctsh ctsh LOC103027348 LOC103027348 Vegfc Vegfc LOC103037830 LOC103037830 plcg1 plcg1 HSPB1 HSPB1 nrp1 nrp1 ENSAMXP00000030449 ENSAMXP00000030449 Bmpr2 Bmpr2 LOC103021920 LOC103021920 W5LTZ3_ASTMX W5LTZ3_ASTMX W5LTS7_ASTMX W5LTS7_ASTMX ARF6 ARF6 W5LQ23_ASTMX W5LQ23_ASTMX tgfbr2 tgfbr2 W5LID2_ASTMX W5LID2_ASTMX atp5f1b atp5f1b bsg bsg LOC103031298 LOC103031298 W5LD95_ASTMX W5LD95_ASTMX W5L7F6_ASTMX W5L7F6_ASTMX atp5f1a atp5f1a mtor mtor Aamp Aamp LOC103035431 LOC103035431 Jcad Jcad LOC103024607 LOC103024607 agt agt W5KQ11_ASTMX W5KQ11_ASTMX nfe2l2 nfe2l2 mst1r mst1r Tek Tek W5KF46_ASTMX W5KF46_ASTMX LOC103041996 LOC103041996 LOC103037777 LOC103037777 rin2 rin2 pik3cg pik3cg Sirt1 Sirt1 tgfb1 tgfb1 W5K3K3_ASTMX W5K3K3_ASTMX LOC103030977 LOC103030977 Bcas3 Bcas3 plcg2 plcg2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103032545Si:ch211-85n16.4. (909 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
ENSAMXP00000054408Si:dkey-206d17.12. (289 aa)
plpp3Phospholipid phosphatase 3. (313 aa)
ENSAMXP00000053597Uncharacterized protein. (1310 aa)
LOC103042476Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
sp1Uncharacterized protein. (678 aa)
sash1SAM and SH3 domain containing 1a. (1358 aa)
ENSAMXP00000050058Uncharacterized protein. (106 aa)
LOC103027828Heparin-binding EGF-like growth factor a. (241 aa)
rab25RAB25, member RAS oncogene family b. (211 aa)
LOC103041475Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
LOC103046764Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC103042520Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (259 aa)
LOC103029481Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (208 aa)
LOC103029863Heat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family. (204 aa)
LOC103047026acidPPc domain-containing protein. (309 aa)
ENSAMXP00000047619CD40 molecule, TNF receptor superfamily member 5. (353 aa)
glipr2GLI pathogenesis-related 2, like; Belongs to the CRISP family. (154 aa)
ENSAMXP00000046398Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (270 aa)
ENSAMXP00000046336RAB25, member RAS oncogene family a. (214 aa)
TSTA3-2Tissue specific transplantation antigen P35B. (322 aa)
gpiGlucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
LOC103029654Epimerase domain-containing protein. (322 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
LOC103038135Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (169 aa)
TSTA3Tissue specific transplantation antigen P35B. (322 aa)
cib1Calcium and integrin binding 1 (calmyrin). (190 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (199 aa)
LOC103040845Nuclear factor, erythroid 2-like 2b. (569 aa)
Itgb1bp1Integrin beta 1 binding protein 1. (184 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
ENSAMXP00000036546SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (584 aa)
capn7Calpain 7; Belongs to the peptidase C2 family. (814 aa)
LOC103041352Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (60 aa)
LOC103029333Epimerase domain-containing protein. (322 aa)
LOC103025626Heparin-binding EGF-like growth factor b. (213 aa)
LOC103032641Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (526 aa)
ENSAMXP00000034094Insulin-like growth factor 2a. (176 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (333 aa)
LOC103027348Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (146 aa)
VegfcVascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (339 aa)
LOC103037830GATA binding protein 2a. (469 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1307 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (182 aa)
nrp1Neuropilin; Belongs to the neuropilin family. (924 aa)
ENSAMXP00000030449Uncharacterized protein. (107 aa)
Bmpr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
LOC103021920JunE proto-oncogene, AP-1 transcription factor subunit. (353 aa)
W5LTZ3_ASTMXADP-ribosylation factor 6b; Belongs to the small GTPase superfamily. Arf family. (120 aa)
W5LTS7_ASTMXMacrophage stimulating 1 receptor a. (1283 aa)
ARF6ADP ribosylation factor 6. (116 aa)
W5LQ23_ASTMXLegumain. (430 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
W5LID2_ASTMXRas responsive element binding protein 1a. (1552 aa)
atp5f1bATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (518 aa)
bsgBasigin. (394 aa)
LOC103031298Glucose-6-phosphate isomerase; Belongs to the GPI family. (557 aa)
W5LD95_ASTMXADAM metallopeptidase domain 17a. (675 aa)
W5L7F6_ASTMXRas responsive element binding protein 1b. (1637 aa)
atp5f1aATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (552 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2518 aa)
AampAngio-associated, migratory cell protein. (377 aa)
LOC103035431Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family. (1085 aa)
JcadJunctional cadherin 5 associated a. (1554 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
agtAngiotensinogen; Belongs to the serpin family. (456 aa)
W5KQ11_ASTMXEpimerase domain-containing protein. (322 aa)
nfe2l2Nuclear factor, erythroid 2-like 2a. (637 aa)
mst1rMacrophage stimulating 1 receptor b. (1375 aa)
TekTEK tyrosine kinase, endothelial. (1137 aa)
W5KF46_ASTMXTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (561 aa)
LOC103041996ADAM metallopeptidase domain 17b. (841 aa)
LOC103037777Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (528 aa)
rin2Ras and Rab interactor 2. (980 aa)
pik3cgPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1105 aa)
Sirt1Deacetylase sirtuin-type domain-containing protein. (802 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
W5K3K3_ASTMXMET proto-oncogene, receptor tyrosine kinase. (1352 aa)
LOC103030977Zinc finger CCCH-type containing 12A. (608 aa)
Bcas3BCAS3 microtubule associated cell migration factor. (829 aa)
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.