STRINGSTRING
rab23 rab23 uba5 uba5 ogt ogt LOC103044705 LOC103044705 vps33a vps33a W5L1E4_ASTMX W5L1E4_ASTMX atg3 atg3 W5KW74_ASTMX W5KW74_ASTMX LOC103034420 LOC103034420 wipi2 wipi2 nbr1 nbr1 ulk1 ulk1 Nod1 Nod1 Ddrgk1 Ddrgk1 lix1 lix1 LOC103027738 LOC103027738 W5KII5_ASTMX W5KII5_ASTMX c6h5orf51 c6h5orf51 W5KC71_ASTMX W5KC71_ASTMX atg5 atg5 atg9a atg9a Tecpr1 Tecpr1 LOC103039768 LOC103039768 nsfl1c nsfl1c trappc8 trappc8 tp53inp1 tp53inp1 ulk3 ulk3 ENSAMXP00000031738 ENSAMXP00000031738 ambra1 ambra1 svip svip ufm1 ufm1 SNX14 SNX14 retreg1 retreg1 atg10 atg10 atg4b atg4b pik3c3 pik3c3 wdr45b wdr45b LOC103045400 LOC103045400 LOC103022286 LOC103022286 stbd1 stbd1 snapin snapin LIX1L LIX1L ENSAMXP00000037278 ENSAMXP00000037278 ENSAMXP00000037763 ENSAMXP00000037763 pacs2 pacs2 ENSAMXP00000050554 ENSAMXP00000050554 map1lc3a map1lc3a Prkn Prkn ulk2 ulk2 snap29 snap29 vps39 vps39 ENSAMXP00000048151 ENSAMXP00000048151 LOC103030324 LOC103030324 atg16l1 atg16l1 Map1lc3b Map1lc3b atg101 atg101 ENSAMXP00000045327 ENSAMXP00000045327 ENSAMXP00000045176 ENSAMXP00000045176 LOC103043048 LOC103043048 Tmem41b Tmem41b wdr81 wdr81 ei24 ei24 wipi1 wipi1 snx7 snx7 ATG14 ATG14 W5JYH4_ASTMX W5JYH4_ASTMX spg11 spg11 LOC103034733 LOC103034733 ATG2B ATG2B LOC103036711 LOC103036711 Gabarapl2 Gabarapl2 rab7a rab7a epg5 epg5 vps41 vps41 spns1 spns1 W5K7R1_ASTMX W5K7R1_ASTMX W5K9U6_ASTMX W5K9U6_ASTMX bag3 bag3 LOC103028654 LOC103028654 LOC103033874 LOC103033874 LOC103040557 LOC103040557 Rab33b Rab33b LOC103037223 LOC103037223 Retreg3 Retreg3 rab43 rab43 LOC103032640 LOC103032640 pjvk pjvk RAB19 RAB19 sting1 sting1 atp13a2 atp13a2 pink1 pink1 taz taz Snx30 Snx30 plaa plaa LOC103035225 LOC103035225 vti1b vti1b ubxn2a ubxn2a map1lc3c map1lc3c ENSAMXP00000053491 ENSAMXP00000053491 RIPK2 RIPK2 stx17 stx17 atg7 atg7 ilrun ilrun atg13 atg13 cln3 cln3 ENSAMXP00000051831 ENSAMXP00000051831 TEX264 TEX264 LOC103032600 LOC103032600 atg12 atg12 LOC103035142 LOC103035142 LOC103021444 LOC103021444 vti1a vti1a ILRUN ILRUN YOD1 YOD1 ENSAMXP00000029991 ENSAMXP00000029991 epm2a epm2a LOC103047478 LOC103047478 TMEM74 TMEM74 emc6 emc6 Plekhm1 Plekhm1 Zfyve26 Zfyve26 W5LMI5_ASTMX W5LMI5_ASTMX wdfy3 wdfy3 Vcp Vcp atg2a atg2a nod2 nod2 zfyve1 zfyve1 LOC103036938 LOC103036938 hdac10 hdac10 Becn1 Becn1 pik3r4 pik3r4 LOC103036389 LOC103036389 retreg2 retreg2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rab23RAB23, member RAS oncogene family. (237 aa)
uba5Ubiquitin-like modifier activating enzyme 5. (401 aa)
ogtO-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1. (1052 aa)
LOC103044705Uncharacterized protein. (122 aa)
vps33aVPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. (600 aa)
W5L1E4_ASTMXAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (744 aa)
atg3Autophagy-related protein 3. (324 aa)
W5KW74_ASTMXSequestosome 1. (427 aa)
LOC103034420ATG16 autophagy related 16-like 2 (S. cerevisiae). (588 aa)
wipi2WD repeat domain, phosphoinositide interacting 2. (425 aa)
nbr1NBR1 autophagy cargo receptor a. (986 aa)
ulk1Unc-51 like autophagy activating kinase 1. (1021 aa)
Nod1Nucleotide-binding oligomerization domain containing 1. (913 aa)
Ddrgk1DDRGK domain containing 1. (148 aa)
lix1Limb and CNS expressed 1. (299 aa)
LOC103027738Si:ch211-11n16.2. (653 aa)
W5KII5_ASTMXTBC1 domain family, member 5. (753 aa)
c6h5orf51Si:dkey-46a10.3. (272 aa)
W5KC71_ASTMXVacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (801 aa)
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
atg9aAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (846 aa)
Tecpr1Tectonin beta-propeller repeat containing 1a. (1223 aa)
LOC103039768GABA(A) receptor-associated protein b. (117 aa)
nsfl1cNSFL1 (p97) cofactor (p47). (371 aa)
trappc8Trafficking protein particle complex 8. (1466 aa)
tp53inp1Tumor protein p53 inducible nuclear protein 1. (242 aa)
ulk3Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (472 aa)
ENSAMXP00000031738CNH domain-containing protein. (322 aa)
ambra1Autophagy/beclin-1 regulator 1b. (1375 aa)
svipSi:ch73-147o17.1. (80 aa)
ufm1Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes. (91 aa)
SNX14Sorting nexin 14. (986 aa)
retreg1Reticulophagy regulator 1. (344 aa)
atg10ATG10 autophagy related 10 homolog (S. cerevisiae). (226 aa)
atg4bCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (396 aa)
pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (884 aa)
wdr45bWD repeat domain 45B. (344 aa)
LOC103045400Zgc:171927. (210 aa)
LOC103022286Sorting nexin 14. (879 aa)
stbd1CBM20 domain-containing protein. (642 aa)
snapinSNAP associated protein. (129 aa)
LIX1LLimb and CNS expressed 1 like. (347 aa)
ENSAMXP00000037278Uncharacterized protein. (220 aa)
ENSAMXP00000037763Ring finger protein 213b. (2724 aa)
pacs2Phosphofurin acidic cluster sorting protein 2. (954 aa)
ENSAMXP00000050554Uncharacterized protein. (724 aa)
map1lc3aMicrotubule-associated protein 1 light chain 3 alpha. (121 aa)
PrknParkin RBR E3 ubiquitin protein ligase. (417 aa)
ulk2Unc-51 like autophagy activating kinase 2. (1040 aa)
snap29Synaptosome associated protein 29. (264 aa)
vps39VPS39 subunit of HOPS complex. (875 aa)
ENSAMXP00000048151UFM1-specific ligase 1. (687 aa)
LOC103030324Tectonin beta-propeller repeat containing 1b. (1143 aa)
atg16l1ATG16 autophagy related 16-like 1 (S. cerevisiae). (601 aa)
Map1lc3bMicrotubule-associated protein 1 light chain 3 beta. (69 aa)
atg101Autophagy related 101. (218 aa)
ENSAMXP00000045327NLRC4_HD2 domain-containing protein. (697 aa)
ENSAMXP00000045176UV radiation resistance associated gene. (683 aa)
LOC103043048RAB7a, member RAS oncogene family. (207 aa)
Tmem41bTransmembrane protein 41B. (108 aa)
wdr81WD repeat domain 81. (2071 aa)
ei24EI24 autophagy associated transmembrane protein. (340 aa)
wipi1WD repeat domain, phosphoinositide interacting 1. (446 aa)
snx7Sorting nexin 7. (466 aa)
ATG14Autophagy related 14. (461 aa)
W5JYH4_ASTMXUnc-51 like autophagy activating kinase 1a. (802 aa)
spg11SPG11 vesicle trafficking associated, spatacsin. (2381 aa)
LOC103034733NBR1 autophagy cargo receptor b. (1003 aa)
ATG2BAutophagy related 2B. (2018 aa)
LOC103036711Vesicle-associated membrane protein 8 (endobrevin). (127 aa)
Gabarapl2GABA(A) receptor-associated protein like 2. (134 aa)
rab7aUncharacterized protein. (214 aa)
epg5Ectopic P-granules autophagy protein 5 homolog (C. elegans). (2553 aa)
vps41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa)
spns1Spinster homolog 1 (Drosophila). (509 aa)
W5K7R1_ASTMXZRAB1B, member RAS oncogene family a. (222 aa)
W5K9U6_ASTMXRB1-inducible coiled-coil 1. (1571 aa)
bag3BCL2 associated athanogene 3. (527 aa)
LOC103028654Uncharacterized protein. (218 aa)
LOC103033874ADP-ribosylation factor-like 8A; Belongs to the small GTPase superfamily. Arf family. (186 aa)
LOC103040557YOD1 deubiquitinase. (342 aa)
Rab33bRAB33B, member RAS oncogene family a. (239 aa)
LOC103037223RAB7b, member RAS oncogene family. (205 aa)
Retreg3Reticulophagy regulator family member 3. (443 aa)
rab43RAB43, member RAS oncogene family. (208 aa)
LOC103032640WD repeat domain 45. (358 aa)
pjvkPejvakin. (369 aa)
RAB19RAB19, member RAS oncogene family. (218 aa)
sting1Transmembrane protein 173. (390 aa)
atp13a2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1170 aa)
pink1PTEN induced kinase 1. (571 aa)
tazTafazzin family protein; Belongs to the taffazin family. (277 aa)
Snx30Sorting nexin family member 30. (416 aa)
plaaPhospholipase A2-activating protein. (798 aa)
LOC103035225RAB1A, member RAS oncogene family b. (202 aa)
vti1bVesicle transport through interaction with t-SNAREs 1B. (225 aa)
ubxn2aUBX domain protein 2A. (248 aa)
map1lc3cMicrotubule-associated protein 1 light chain 3 gamma. (134 aa)
ENSAMXP00000053491Uncharacterized protein. (237 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (579 aa)
stx17Syntaxin 17; Belongs to the syntaxin family. (297 aa)
atg7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (709 aa)
ilrunInflammation and lipid regulator with UBA-like and NBR1-like domains. (283 aa)
atg13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (546 aa)
cln3Battenin. (438 aa)
ENSAMXP00000051831Rubicon like autophagy enhancer. (465 aa)
TEX264Testis expressed 264, ER-phagy receptor. (177 aa)
LOC103032600ADP-ribosylation factor-like 8Bb; Belongs to the small GTPase superfamily. Arf family. (186 aa)
atg12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (109 aa)
LOC103035142Prohibitin. (340 aa)
LOC103021444Lysosomal-associated membrane protein 2. (380 aa)
vti1aVesicle transport through interaction with t-SNAREs 1A. (224 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (279 aa)
YOD1YOD1 deubiquitinase. (318 aa)
ENSAMXP00000029991Uncharacterized protein. (214 aa)
epm2aEPM2A glucan phosphatase, laforin. (317 aa)
LOC103047478Prohibitin. (303 aa)
TMEM74Transmembrane protein 74. (222 aa)
emc6ER membrane protein complex subunit 6. (110 aa)
Plekhm1Pleckstrin homology domain containing, family M (with RUN domain) member 1. (1032 aa)
Zfyve26Zinc finger, FYVE domain containing 26. (2552 aa)
W5LMI5_ASTMXUncharacterized protein. (198 aa)
wdfy3WD repeat and FYVE domain containing 3. (3494 aa)
VcpZgc:136908; Belongs to the AAA ATPase family. (746 aa)
atg2aAutophagy related 2A. (2016 aa)
nod2Nucleotide-binding oligomerization domain containing 2. (908 aa)
zfyve1Zinc finger, FYVE domain containing 1. (774 aa)
LOC103036938ADP-ribosylation factor-like 8Ba; Belongs to the small GTPase superfamily. Arf family. (204 aa)
hdac10Histone deacetylase 10. (683 aa)
Becn1Beclin 1, autophagy related. (422 aa)
pik3r4Phosphoinositide-3-kinase, regulatory subunit 4. (1342 aa)
LOC103036389Testis expressed 264, ER-phagy receptor a. (319 aa)
retreg2Reticulophagy regulator family member 2. (574 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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