(48 nodes) Negative regulation of angiogenesis network (Astyanax mexicanus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	LOC103043405	Chondromodulin. (373 aa)
	LOC103027441	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (266 aa)
	LOC103041009	Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
	LOC103031445	Thrombospondin 1b. (1178 aa)
	W5KGH6_ASTMX	Neurofibromin 1b. (2733 aa)
	Adgrb3	Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1527 aa)
	LOC103043091	Elastin microfibril interfacer 1a. (1050 aa)
	W5KT32_ASTMX	Neurofibromin 1a. (2744 aa)
	W5L1S8_ASTMX	Adhesion G protein-coupled receptor B1a; Belongs to the G-protein coupled receptor 2 family. (1518 aa)
	VASH1	Vasohibin 1. (395 aa)
	ROCK1	Rho-associated, coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. (407 aa)
	CNMD	Chondromodulin. (403 aa)
	LOC103041169	YjeF N-terminal domain containing 3. (246 aa)
	sars1	Seryl-tRNA synthetase. (520 aa)
	W5LNI4_ASTMX	Adhesion G protein-coupled receptor B1b. (612 aa)
	krit1	KRIT1 ankyrin repeat containing. (741 aa)
	S1pr1	Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (376 aa)
	cldn5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	ENSAMXP00000027904	Uncharacterized protein. (337 aa)
	thbs2	Thrombospondin 2b. (1182 aa)
	ENSAMXP00000029792	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (387 aa)
	vash2	Vasohibin 2. (376 aa)
	LOC103042500	Ephrin-A3a; Belongs to the ephrin family. (224 aa)
	ENSAMXP00000037958	GAIN domain-containing protein. (240 aa)
	LOC103042784	Rho-associated, coiled-coil containing protein kinase 2a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1459 aa)
	ENSAMXP00000039289	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family. (295 aa)
	serpine1	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (401 aa)
	rgcc	Regulator of cell cycle. (128 aa)
	LOC103029638	Growth arrest and DNA-damage-inducible, alpha, a. (163 aa)
	ENSAMXP00000042872	Uncharacterized protein. (98 aa)
	Hgs	Hepatocyte growth factor-regulated tyrosine kinase substrate. (688 aa)
	LOC103047654	YjeF N-terminal domain-containing protein. (247 aa)
	ENSAMXP00000043794	Uncharacterized protein. (375 aa)
	Wisp3	Cellular communication network factor 6. (325 aa)
	ENSAMXP00000044530	Elastin microfibril interfacer 1b. (992 aa)
	LOC111190962	Interleukin 17a/f1. (147 aa)
	Tnmd	Tenomodulin. (277 aa)
	ENSAMXP00000046111	Phorbol-ester/DAG-type domain-containing protein. (143 aa)
	mecp2	Methyl CpG binding protein 2. (612 aa)
	tbc1d31	TBC1 domain family, member 31. (1083 aa)
	ENSAMXP00000049202	Uncharacterized protein. (298 aa)
	apoh	Apolipoprotein H. (351 aa)
	Thbs1	Thrombospondin 1a. (1133 aa)
	LOC103042476	Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
	efna3	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (246 aa)
	gadd45a	Growth arrest and DNA-damage-inducible, alpha, b. (159 aa)
	Adgrb2	Uncharacterized protein. (564 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adgrb2	ENSAMXP00000027904	ENSAMXP00000053130	ENSAMXP00000027904	Uncharacterized protein.	Uncharacterized protein.	0.453
Adgrb2	ENSAMXP00000039289	ENSAMXP00000053130	ENSAMXP00000039289	Uncharacterized protein.	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	0.712
ENSAMXP00000027904	Adgrb2	ENSAMXP00000027904	ENSAMXP00000053130	Uncharacterized protein.	Uncharacterized protein.	0.453
ENSAMXP00000027904	ENSAMXP00000037958	ENSAMXP00000027904	ENSAMXP00000037958	Uncharacterized protein.	GAIN domain-containing protein.	0.883
ENSAMXP00000027904	ENSAMXP00000039289	ENSAMXP00000027904	ENSAMXP00000039289	Uncharacterized protein.	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	0.847
ENSAMXP00000027904	W5LNI4_ASTMX	ENSAMXP00000027904	ENSAMXP00000021396	Uncharacterized protein.	Adhesion G protein-coupled receptor B1b.	0.641
ENSAMXP00000029792	cldn5	ENSAMXP00000029792	ENSAMXP00000026626	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.657
ENSAMXP00000037958	ENSAMXP00000027904	ENSAMXP00000037958	ENSAMXP00000027904	GAIN domain-containing protein.	Uncharacterized protein.	0.883
ENSAMXP00000037958	ENSAMXP00000039289	ENSAMXP00000037958	ENSAMXP00000039289	GAIN domain-containing protein.	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	0.899
ENSAMXP00000037958	ENSAMXP00000043794	ENSAMXP00000037958	ENSAMXP00000043794	GAIN domain-containing protein.	Uncharacterized protein.	0.773
ENSAMXP00000037958	W5LNI4_ASTMX	ENSAMXP00000037958	ENSAMXP00000021396	GAIN domain-containing protein.	Adhesion G protein-coupled receptor B1b.	0.886
ENSAMXP00000039289	Adgrb2	ENSAMXP00000039289	ENSAMXP00000053130	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.712
ENSAMXP00000039289	ENSAMXP00000027904	ENSAMXP00000039289	ENSAMXP00000027904	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.847
ENSAMXP00000039289	ENSAMXP00000037958	ENSAMXP00000039289	ENSAMXP00000037958	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	GAIN domain-containing protein.	0.899
ENSAMXP00000039289	ENSAMXP00000049202	ENSAMXP00000039289	ENSAMXP00000049202	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.563
ENSAMXP00000042872	Hgs	ENSAMXP00000042872	ENSAMXP00000043019	Uncharacterized protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.631
ENSAMXP00000043794	ENSAMXP00000037958	ENSAMXP00000043794	ENSAMXP00000037958	Uncharacterized protein.	GAIN domain-containing protein.	0.773
ENSAMXP00000043794	W5LNI4_ASTMX	ENSAMXP00000043794	ENSAMXP00000021396	Uncharacterized protein.	Adhesion G protein-coupled receptor B1b.	0.884
ENSAMXP00000046111	ROCK1	ENSAMXP00000046111	ENSAMXP00000015120	Phorbol-ester/DAG-type domain-containing protein.	Rho-associated, coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily.	0.864
ENSAMXP00000049202	ENSAMXP00000039289	ENSAMXP00000049202	ENSAMXP00000039289	Uncharacterized protein.	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.	0.563