(24 nodes) Acid-amino acid ligase activity network (Astyanax mexicanus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	ENSAMXP00000054563	Fleer. (691 aa)
	ppcs	Phosphopantothenoylcysteine synthetase. (319 aa)
	ttl	Tubulin tyrosine ligase. (406 aa)
	fpgs	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (582 aa)
	ttll7	Tubulin tyrosine ligase-like family, member 7. (927 aa)
	tpgs1	Uncharacterized protein. (292 aa)
	gclm	Glutamate-cysteine ligase, modifier subunit. (271 aa)
	ENSAMXP00000048911	AIRC domain-containing protein. (1035 aa)
	ttll10	Tubulin tyrosine ligase-like family, member 10. (788 aa)
	Ghdc	GH3 domain containing. (463 aa)
	ttll11	Tubulin tyrosine ligase-like family, member 11. (720 aa)
	ENSAMXP00000037481	Uncharacterized protein. (133 aa)
	ttll1	Tubulin tyrosine ligase-like family, member 1. (443 aa)
	ttll4	Tubulin tyrosine ligase-like family, member 4. (1141 aa)
	ENSAMXP00000031318	Coiled-coil domain containing 30. (532 aa)
	ttll5	Tubulin tyrosine ligase-like family, member 5. (1358 aa)
	Ttll9	Tubulin tyrosine ligase-like family, member 9. (443 aa)
	ENSAMXP00000029605	Uncharacterized protein. (62 aa)
	cep41	Centrosomal protein 41. (367 aa)
	TTLL2	Tubulin tyrosine ligase like 2. (577 aa)
	gss	Glutathione synthetase. (477 aa)
	LOC103039118	Uncharacterized protein. (792 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (629 aa)
	ttll6	Tubulin tyrosine ligase-like family, member 6. (784 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000029605	gclm	ENSAMXP00000029605	ENSAMXP00000049121	Uncharacterized protein.	Glutamate-cysteine ligase, modifier subunit.	0.966
ENSAMXP00000029605	gss	ENSAMXP00000029605	ENSAMXP00000018152	Uncharacterized protein.	Glutathione synthetase.	0.910
ENSAMXP00000031318	fpgs	ENSAMXP00000031318	ENSAMXP00000052537	Coiled-coil domain containing 30.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.411
ENSAMXP00000037481	tpgs1	ENSAMXP00000037481	ENSAMXP00000051174	Uncharacterized protein.	Uncharacterized protein.	0.460
ENSAMXP00000054563	ttll6	ENSAMXP00000054563	ENSAMXP00000009212	Fleer.	Tubulin tyrosine ligase-like family, member 6.	0.495
LOC103039118	tpgs1	ENSAMXP00000016034	ENSAMXP00000051174	Uncharacterized protein.	Uncharacterized protein.	0.460
TTLL2	tpgs1	ENSAMXP00000018408	ENSAMXP00000051174	Tubulin tyrosine ligase like 2.	Uncharacterized protein.	0.460
Ttll9	ttll11	ENSAMXP00000030048	ENSAMXP00000043271	Tubulin tyrosine ligase-like family, member 9.	Tubulin tyrosine ligase-like family, member 11.	0.483
Ttll9	ttll5	ENSAMXP00000030048	ENSAMXP00000030395	Tubulin tyrosine ligase-like family, member 9.	Tubulin tyrosine ligase-like family, member 5.	0.574
cep41	ttll1	ENSAMXP00000029228	ENSAMXP00000036638	Centrosomal protein 41.	Tubulin tyrosine ligase-like family, member 1.	0.564
cep41	ttll5	ENSAMXP00000029228	ENSAMXP00000030395	Centrosomal protein 41.	Tubulin tyrosine ligase-like family, member 5.	0.410
cep41	ttll6	ENSAMXP00000029228	ENSAMXP00000009212	Centrosomal protein 41.	Tubulin tyrosine ligase-like family, member 6.	0.580
fpgs	ENSAMXP00000031318	ENSAMXP00000052537	ENSAMXP00000031318	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Coiled-coil domain containing 30.	0.411
fpgs	ppcs	ENSAMXP00000052537	ENSAMXP00000054517	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Phosphopantothenoylcysteine synthetase.	0.411
gclc	gclm	ENSAMXP00000013038	ENSAMXP00000049121	Glutamate-cysteine ligase, catalytic subunit.	Glutamate-cysteine ligase, modifier subunit.	0.996
gclc	gss	ENSAMXP00000013038	ENSAMXP00000018152	Glutamate-cysteine ligase, catalytic subunit.	Glutathione synthetase.	0.990
gclm	ENSAMXP00000029605	ENSAMXP00000049121	ENSAMXP00000029605	Glutamate-cysteine ligase, modifier subunit.	Uncharacterized protein.	0.966
gclm	gclc	ENSAMXP00000049121	ENSAMXP00000013038	Glutamate-cysteine ligase, modifier subunit.	Glutamate-cysteine ligase, catalytic subunit.	0.996
gclm	gss	ENSAMXP00000049121	ENSAMXP00000018152	Glutamate-cysteine ligase, modifier subunit.	Glutathione synthetase.	0.988
gss	ENSAMXP00000029605	ENSAMXP00000018152	ENSAMXP00000029605	Glutathione synthetase.	Uncharacterized protein.	0.910