57 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAMXP00000051081	AGC-kinase C-terminal domain-containing protein. (50 aa)
	hipk2	Homeodomain interacting protein kinase 2. (1245 aa)
	BCL2	BCL2 apoptosis regulator. (201 aa)
	oxsr1	Oxidative stress responsive kinase 1b. (563 aa)
	LOC103022926	3-phosphoinositide dependent protein kinase 1a. (539 aa)
	W5K5Y3_ASTMX	Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b. (750 aa)
	LOC103027970	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (478 aa)
	W5K8N8_ASTMX	Rho-associated, coiled-coil containing protein kinase 2b; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1302 aa)
	haspin	Si:dkeyp-26a9.2. (1225 aa)
	LOC103023558	Homeodomain interacting protein kinase 1a. (1153 aa)
	Nlk	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (515 aa)
	W5KF46_ASTMX	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (561 aa)
	Prkdc	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4082 aa)
	LOC103034036	Dual specificity tyrosine phosphorylation regulated kinase 3. (585 aa)
	W5KKG9_ASTMX	Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B. (646 aa)
	Dyrk1a	Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a. (740 aa)
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (421 aa)
	stk11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (437 aa)
	LOC103025973	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	LOC103046977	Homeodomain interacting protein kinase 3a. (1313 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2518 aa)
	ROCK1	Rho-associated, coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. (407 aa)
	W5L6U8_ASTMX	Protein kinase C. (646 aa)
	W5L9B7_ASTMX	Protein kinase C, gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1262 aa)
	Lrrk2	Leucine-rich repeat kinase 2. (2537 aa)
	dyrk2	Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2. (586 aa)
	tgfbr2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
	Cdc42bpa	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1701 aa)
	LOC103030869	Uncharacterized protein. (465 aa)
	dmpk	Uncharacterized protein. (604 aa)
	ENSAMXP00000030289	Uncharacterized protein. (544 aa)
	chek1	Checkpoint kinase 1; Belongs to the protein kinase superfamily. (464 aa)
	Cdc42bpb	CDC42 binding protein kinase beta (DMPK-like); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1771 aa)
	ENSAMXP00000032027	Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (453 aa)
	LOC103046273	Si:ch211-1e14.1. (1791 aa)
	gsk3a	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
	LOC103047733	Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (409 aa)
	ENSAMXP00000034135	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa)
	LOC103043574	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (420 aa)
	ENSAMXP00000035791	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa)
	LOC103042784	Rho-associated, coiled-coil containing protein kinase 2a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1459 aa)
	stk39	Serine threonine kinase 39. (559 aa)
	LOC103042686	Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily. (392 aa)
	ENSAMXP00000040981	Uncharacterized protein. (78 aa)
	LOC103033547	3-phosphoinositide dependent protein kinase 1b. (537 aa)
	LOC103028340	Casein kinase 2, alpha 1 polypeptide; Belongs to the protein kinase superfamily. (394 aa)
	LOC103042559	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
	LOC103032471	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (429 aa)
	LOC103039548	BCL2 apoptosis regulator. (218 aa)
	prkcb	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
	ENSAMXP00000045222	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (581 aa)
	ENSAMXP00000046111	Phorbol-ester/DAG-type domain-containing protein. (143 aa)
	LOC103022299	Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (420 aa)
	dyrk4	Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4. (655 aa)
	csnk2a2	Casein kinase 2, alpha prime polypeptide b; Belongs to the protein kinase superfamily. (350 aa)
	ENSAMXP00000050254	Protein kinase domain-containing protein. (55 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000030289	ENSAMXP00000034135	ENSAMXP00000030289	ENSAMXP00000034135	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.457
ENSAMXP00000032027	ENSAMXP00000035791	ENSAMXP00000032027	ENSAMXP00000035791	Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.443
ENSAMXP00000032027	LOC103028340	ENSAMXP00000032027	ENSAMXP00000043645	Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily.	Casein kinase 2, alpha 1 polypeptide; Belongs to the protein kinase superfamily.	0.441
ENSAMXP00000032027	LOC103042686	ENSAMXP00000032027	ENSAMXP00000040542	Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily.	Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily.	0.441
ENSAMXP00000034135	ENSAMXP00000030289	ENSAMXP00000034135	ENSAMXP00000030289	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.457
ENSAMXP00000035791	ENSAMXP00000032027	ENSAMXP00000035791	ENSAMXP00000032027	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily.	0.443
ENSAMXP00000035791	csnk2a2	ENSAMXP00000035791	ENSAMXP00000049732	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Casein kinase 2, alpha prime polypeptide b; Belongs to the protein kinase superfamily.	0.441
ENSAMXP00000045222	LOC103022926	ENSAMXP00000045222	ENSAMXP00000002818	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	3-phosphoinositide dependent protein kinase 1a.	0.431
ENSAMXP00000045222	LOC103033547	ENSAMXP00000045222	ENSAMXP00000042666	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	3-phosphoinositide dependent protein kinase 1b.	0.431
ENSAMXP00000046111	ROCK1	ENSAMXP00000046111	ENSAMXP00000015120	Phorbol-ester/DAG-type domain-containing protein.	Rho-associated, coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily.	0.864
ENSAMXP00000046111	dmpk	ENSAMXP00000046111	ENSAMXP00000029282	Phorbol-ester/DAG-type domain-containing protein.	Uncharacterized protein.	0.533
ENSAMXP00000051081	LOC103022926	ENSAMXP00000051081	ENSAMXP00000002818	AGC-kinase C-terminal domain-containing protein.	3-phosphoinositide dependent protein kinase 1a.	0.431
ENSAMXP00000051081	LOC103033547	ENSAMXP00000051081	ENSAMXP00000042666	AGC-kinase C-terminal domain-containing protein.	3-phosphoinositide dependent protein kinase 1b.	0.431
LOC103022926	ENSAMXP00000045222	ENSAMXP00000002818	ENSAMXP00000045222	3-phosphoinositide dependent protein kinase 1a.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.431
LOC103022926	ENSAMXP00000051081	ENSAMXP00000002818	ENSAMXP00000051081	3-phosphoinositide dependent protein kinase 1a.	AGC-kinase C-terminal domain-containing protein.	0.431
LOC103022926	LOC103025973	ENSAMXP00000002818	ENSAMXP00000012293	3-phosphoinositide dependent protein kinase 1a.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.431
LOC103022926	LOC103033547	ENSAMXP00000002818	ENSAMXP00000042666	3-phosphoinositide dependent protein kinase 1a.	3-phosphoinositide dependent protein kinase 1b.	0.901
LOC103022926	Prkdc	ENSAMXP00000002818	ENSAMXP00000007361	3-phosphoinositide dependent protein kinase 1a.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.412
LOC103022926	W5L6U8_ASTMX	ENSAMXP00000002818	ENSAMXP00000015560	3-phosphoinositide dependent protein kinase 1a.	Protein kinase C.	0.431
LOC103022926	W5L9B7_ASTMX	ENSAMXP00000002818	ENSAMXP00000016429	3-phosphoinositide dependent protein kinase 1a.	Protein kinase C, gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.431