(24 nodes) Desmosome network (Astyanax mexicanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103031848	Junctional adhesion molecule 3b. (314 aa)
	LOC103025382	Plakophilin 3b. (792 aa)
	klhl6	BTB domain-containing protein. (614 aa)
	pof1b	POF1B actin binding protein. (529 aa)
	pkp2	Plakophilin 2. (787 aa)
	LOC103026629	BTB domain-containing protein. (600 aa)
	KLHL35	Kelch like family member 35. (545 aa)
	LOC103029649	Kelch-like family member 24a. (599 aa)
	LOC103046265	Plakophilin 3a. (896 aa)
	LOC103045821	Junction plakoglobin a. (724 aa)
	ENSAMXP00000028268	Kazrin, periplakin interacting protein b. (499 aa)
	ENSAMXP00000034482	Kazrin, periplakin interacting protein a. (630 aa)
	ENSAMXP00000037896	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (973 aa)
	pnn	Pinin, desmosome associated protein. (741 aa)
	LOC103034870	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1086 aa)
	LOC103021864	Si:ch211-256e16.3. (621 aa)
	W5KDJ8_ASTMX	Junction plakoglobin b. (709 aa)
	LOC103035083	Vinculin b. (1065 aa)
	Pkp1	Plakophilin 1b. (770 aa)
	jam3	Junctional adhesion molecule 3a. (307 aa)
	LOC103038989	Vinculin a. (1131 aa)
	W5K4G3_ASTMX	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1233 aa)
	W5K4F8_ASTMX	Si:ch73-74h11.1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1063 aa)
	LOC103034091	Desmocollin 2 like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (897 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000037896	LOC103025382	ENSAMXP00000037896	ENSAMXP00000006241	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Plakophilin 3b.	0.606
ENSAMXP00000037896	LOC103034091	ENSAMXP00000037896	ENSAMXP00000002450	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Desmocollin 2 like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.747
ENSAMXP00000037896	LOC103045821	ENSAMXP00000037896	ENSAMXP00000018907	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Junction plakoglobin a.	0.656
ENSAMXP00000037896	LOC103046265	ENSAMXP00000037896	ENSAMXP00000018405	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Plakophilin 3a.	0.606
ENSAMXP00000037896	Pkp1	ENSAMXP00000037896	ENSAMXP00000051949	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Plakophilin 1b.	0.652
ENSAMXP00000037896	W5KDJ8_ASTMX	ENSAMXP00000037896	ENSAMXP00000005659	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Junction plakoglobin b.	0.656
ENSAMXP00000037896	pkp2	ENSAMXP00000037896	ENSAMXP00000007434	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Plakophilin 2.	0.711
LOC103025382	ENSAMXP00000037896	ENSAMXP00000006241	ENSAMXP00000037896	Plakophilin 3b.	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.606
LOC103025382	LOC103034091	ENSAMXP00000006241	ENSAMXP00000002450	Plakophilin 3b.	Desmocollin 2 like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.722
LOC103025382	LOC103034870	ENSAMXP00000006241	ENSAMXP00000041186	Plakophilin 3b.	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.606
LOC103025382	LOC103035083	ENSAMXP00000006241	ENSAMXP00000050422	Plakophilin 3b.	Vinculin b.	0.420
LOC103025382	LOC103038989	ENSAMXP00000006241	ENSAMXP00000004908	Plakophilin 3b.	Vinculin a.	0.420
LOC103025382	LOC103045821	ENSAMXP00000006241	ENSAMXP00000018907	Plakophilin 3b.	Junction plakoglobin a.	0.627
LOC103025382	W5K4F8_ASTMX	ENSAMXP00000006241	ENSAMXP00000002469	Plakophilin 3b.	Si:ch73-74h11.1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.606
LOC103025382	W5K4G3_ASTMX	ENSAMXP00000006241	ENSAMXP00000002474	Plakophilin 3b.	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.606
LOC103025382	W5KDJ8_ASTMX	ENSAMXP00000006241	ENSAMXP00000005659	Plakophilin 3b.	Junction plakoglobin b.	0.627
LOC103025382	pkp2	ENSAMXP00000006241	ENSAMXP00000007434	Plakophilin 3b.	Plakophilin 2.	0.401
LOC103031848	jam3	ENSAMXP00000049963	ENSAMXP00000054139	Junctional adhesion molecule 3b.	Junctional adhesion molecule 3a.	0.901
LOC103034091	ENSAMXP00000037896	ENSAMXP00000002450	ENSAMXP00000037896	Desmocollin 2 like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.747
LOC103034091	LOC103025382	ENSAMXP00000002450	ENSAMXP00000006241	Desmocollin 2 like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Plakophilin 3b.	0.722