(16 nodes) Heparin metabolic process network (Astyanax mexicanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAMXP00000040799	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3. (846 aa)
	ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b. (886 aa)
	ext2	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (720 aa)
	LOC103040160	Glucuronic acid epimerase a. (584 aa)
	LOC103040217	Glucuronic acid epimerase b. (586 aa)
	ENSAMXP00000040119	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (404 aa)
	LOC103038164	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a. (881 aa)
	ENSAMXP00000033131	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (475 aa)
	LOC107197257	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (451 aa)
	hs2st1	Heparan sulfate 2-O-sulfotransferase 1a. (355 aa)
	LOC103043510	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (421 aa)
	ndst2	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2a. (888 aa)
	LOC103031986	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b. (888 aa)
	W5KFE2_ASTMX	Heparan sulfate 2-O-sulfotransferase 1b. (312 aa)
	W5KAH7_ASTMX	Iduronidase alpha-L-. (595 aa)
	LOC103043104	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (444 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000033131	ENSAMXP00000040119	ENSAMXP00000033131	ENSAMXP00000040119	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	0.582
ENSAMXP00000033131	LOC103043104	ENSAMXP00000033131	ENSAMXP00000001895	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.590
ENSAMXP00000033131	LOC103043510	ENSAMXP00000033131	ENSAMXP00000029735	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.582
ENSAMXP00000033131	LOC107197257	ENSAMXP00000033131	ENSAMXP00000032052	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.902
ENSAMXP00000040119	ENSAMXP00000033131	ENSAMXP00000040119	ENSAMXP00000033131	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.582
ENSAMXP00000040119	LOC103043104	ENSAMXP00000040119	ENSAMXP00000001895	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.902
ENSAMXP00000040119	LOC103043510	ENSAMXP00000040119	ENSAMXP00000029735	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.901
ENSAMXP00000040119	LOC107197257	ENSAMXP00000040119	ENSAMXP00000032052	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.581
ENSAMXP00000040799	LOC103038164	ENSAMXP00000040799	ENSAMXP00000039237	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3.	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a.	0.450
ENSAMXP00000040799	LOC103040160	ENSAMXP00000040799	ENSAMXP00000043976	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3.	Glucuronic acid epimerase a.	0.464
ENSAMXP00000040799	LOC103040217	ENSAMXP00000040799	ENSAMXP00000041985	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3.	Glucuronic acid epimerase b.	0.525
ENSAMXP00000040799	ndst1	ENSAMXP00000040799	ENSAMXP00000046596	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3.	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b.	0.449
LOC103031986	LOC103038164	ENSAMXP00000017200	ENSAMXP00000039237	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b.	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a.	0.901
LOC103031986	LOC103040160	ENSAMXP00000017200	ENSAMXP00000043976	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b.	Glucuronic acid epimerase a.	0.930
LOC103031986	LOC103040217	ENSAMXP00000017200	ENSAMXP00000041985	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b.	Glucuronic acid epimerase b.	0.936
LOC103031986	ext2	ENSAMXP00000017200	ENSAMXP00000045110	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b.	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	0.433
LOC103031986	ndst1	ENSAMXP00000017200	ENSAMXP00000046596	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b.	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b.	0.901
LOC103031986	ndst2	ENSAMXP00000017200	ENSAMXP00000021799	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b.	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2a.	0.901
LOC103038164	ENSAMXP00000040799	ENSAMXP00000039237	ENSAMXP00000040799	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a.	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3.	0.450
LOC103038164	LOC103031986	ENSAMXP00000039237	ENSAMXP00000017200	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a.	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b.	0.901