74 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103027433	Si:ch211-130m23.5. (682 aa)
	ENSAMXP00000051399	Ig_4 domain-containing protein. (220 aa)
	ENSAMXP00000052407	Uncharacterized protein. (152 aa)
	nkx2-3	NK2 homeobox 3. (328 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (579 aa)
	W5K0L4_ASTMX	MADS-box domain-containing protein. (479 aa)
	LOC103041682	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (331 aa)
	abl2	Tyrosine-protein kinase. (1149 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
	LOC103029511	Ig-like domain-containing protein. (224 aa)
	LOC103040345	Ring finger and CCCH-type domains 2. (1061 aa)
	fadd	Fas (tnfrsf6)-associated via death domain. (190 aa)
	LOC103030080	Prostaglandin E receptor 4 (subtype EP4) b. (464 aa)
	Lig4	DNA ligase. (966 aa)
	themis	Thymocyte selection associated. (678 aa)
	W5KMM6_ASTMX	TSC complex subunit 1b. (1211 aa)
	stk11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (437 aa)
	LOC103024607	Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
	card11	Caspase recruitment domain family, member 11. (1126 aa)
	Tbx21	T-box transcription factor 21. (577 aa)
	LOC103027415	Interferon regulatory factor. (310 aa)
	jak1	Tyrosine-protein kinase. (1159 aa)
	lepr	Leptin receptor. (1117 aa)
	agtpbp1	ATP/GTP binding protein 1. (1157 aa)
	W5KYV3_ASTMX	SEFIR domain-containing protein. (102 aa)
	hlx	H2.0-like homeo box 1 (Drosophila). (374 aa)
	batf	Basic leucine zipper transcription factor, ATF-like. (123 aa)
	traf3ip2	SEFIR domain-containing protein. (427 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2518 aa)
	sp3	Sp3a transcription factor. (710 aa)
	W5L9B2_ASTMX	Transcription factor 7. (442 aa)
	tsc1	TSC complex subunit 1a. (1148 aa)
	Rag1	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1042 aa)
	foxn1	Forkhead box N1. (582 aa)
	LOC103044144	Tyrosine-protein kinase. (1152 aa)
	LOC103035115	Ring finger and CCCH-type domains 1b. (1124 aa)
	rag2	Recombination activating gene 2. (531 aa)
	zbtb1	Zinc finger and BTB domain containing 1. (680 aa)
	Gpr183	G protein-coupled receptor 183a; Belongs to the G-protein coupled receptor 1 family. (370 aa)
	Gpr18	G protein-coupled receptor 18. (340 aa)
	Fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (584 aa)
	SRF	Serum response factor. (527 aa)
	ENSAMXP00000029463	TRAF3 interacting protein 2-like. (421 aa)
	prr7	Proline rich 7, synaptic. (253 aa)
	sash3	SAM and SH3 domain containing 3. (383 aa)
	ENSAMXP00000030634	Proteasome subunit beta 11. (150 aa)
	il6r	Interleukin 6 receptor. (591 aa)
	rabl3	RAB, member of RAS oncogene family-like 3. (233 aa)
	LOC103025471	Prostaglandin E receptor 4 (subtype EP4) a; Belongs to the G-protein coupled receptor 1 family. (452 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (809 aa)
	ENSAMXP00000036986	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
	LOC103044019	Tyrosine-protein kinase. (612 aa)
	ENSAMXP00000037604	Ig-like domain-containing protein. (189 aa)
	ENSAMXP00000037899	MADS-box domain-containing protein. (356 aa)
	ENSAMXP00000039005	Uncharacterized protein. (154 aa)
	rc3h1	Ring finger and CCCH-type domains 1a. (1106 aa)
	abl1	Tyrosine-protein kinase. (1107 aa)
	ccr7	Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family. (368 aa)
	armc5	Armadillo repeat containing 5. (1233 aa)
	Syk	Tyrosine-protein kinase. (631 aa)
	tmem98	Transmembrane protein 98. (222 aa)
	ENSAMXP00000041417	ATP/GTP binding protein-like 1. (1078 aa)
	ENSAMXP00000041728	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily. (351 aa)
	themis2	Thymocyte selection associated family member 2. (693 aa)
	ENSAMXP00000042552	Uncharacterized protein. (809 aa)
	ENSAMXP00000044183	CD83 molecule. (150 aa)
	lef1	Lymphoid enhancer-binding factor 1. (384 aa)
	ENSAMXP00000045056	Thymocyte expressed, positive selection associated 1. (512 aa)
	il7r	Interleukin 7 receptor. (380 aa)
	LOC103030342	Sp3b transcription factor. (658 aa)
	ENSAMXP00000046400	Proteasome subunit beta11b. (379 aa)
	LOC103033011	Prostaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family. (463 aa)
	LOC111192370	Ig_4 domain-containing protein. (189 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000037604	ccr7	ENSAMXP00000037604	ENSAMXP00000040044	Ig-like domain-containing protein.	Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.440
ENSAMXP00000039005	ENSAMXP00000042552	ENSAMXP00000039005	ENSAMXP00000042552	Uncharacterized protein.	Uncharacterized protein.	0.548
ENSAMXP00000039005	ENSAMXP00000051399	ENSAMXP00000039005	ENSAMXP00000051399	Uncharacterized protein.	Ig_4 domain-containing protein.	0.948
ENSAMXP00000039005	LOC103029511	ENSAMXP00000039005	ENSAMXP00000006898	Uncharacterized protein.	Ig-like domain-containing protein.	0.826
ENSAMXP00000039005	LOC103044019	ENSAMXP00000039005	ENSAMXP00000037388	Uncharacterized protein.	Tyrosine-protein kinase.	0.744
ENSAMXP00000039005	LOC111192370	ENSAMXP00000039005	ENSAMXP00000048310	Uncharacterized protein.	Ig_4 domain-containing protein.	0.948
ENSAMXP00000039005	PTPRC	ENSAMXP00000039005	ENSAMXP00000032906	Uncharacterized protein.	Protein tyrosine phosphatase receptor type C.	0.548
ENSAMXP00000039005	Syk	ENSAMXP00000039005	ENSAMXP00000040943	Uncharacterized protein.	Tyrosine-protein kinase.	0.744
ENSAMXP00000039005	ccr7	ENSAMXP00000039005	ENSAMXP00000040044	Uncharacterized protein.	Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.424
ENSAMXP00000039005	il7r	ENSAMXP00000039005	ENSAMXP00000045147	Uncharacterized protein.	Interleukin 7 receptor.	0.643
ENSAMXP00000041728	ENSAMXP00000051399	ENSAMXP00000041728	ENSAMXP00000051399	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.	Ig_4 domain-containing protein.	0.439
ENSAMXP00000041728	LOC111192370	ENSAMXP00000041728	ENSAMXP00000048310	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.	Ig_4 domain-containing protein.	0.439
ENSAMXP00000041728	card11	ENSAMXP00000041728	ENSAMXP00000010096	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.	Caspase recruitment domain family, member 11.	0.417
ENSAMXP00000041728	fadd	ENSAMXP00000041728	ENSAMXP00000007593	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.	Fas (tnfrsf6)-associated via death domain.	0.990
ENSAMXP00000042552	ENSAMXP00000039005	ENSAMXP00000042552	ENSAMXP00000039005	Uncharacterized protein.	Uncharacterized protein.	0.548
ENSAMXP00000042552	ENSAMXP00000051399	ENSAMXP00000042552	ENSAMXP00000051399	Uncharacterized protein.	Ig_4 domain-containing protein.	0.605
ENSAMXP00000042552	ENSAMXP00000052407	ENSAMXP00000042552	ENSAMXP00000052407	Uncharacterized protein.	Uncharacterized protein.	0.548
ENSAMXP00000042552	LOC103027433	ENSAMXP00000042552	ENSAMXP00000050677	Uncharacterized protein.	Si:ch211-130m23.5.	0.548
ENSAMXP00000042552	LOC103029511	ENSAMXP00000042552	ENSAMXP00000006898	Uncharacterized protein.	Ig-like domain-containing protein.	0.596
ENSAMXP00000042552	LOC111192370	ENSAMXP00000042552	ENSAMXP00000048310	Uncharacterized protein.	Ig_4 domain-containing protein.	0.605