48 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103038759	Golgi glycoprotein 1b. (1147 aa)
	wfikkn1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (565 aa)
	ENSAMXP00000049240	Uncharacterized protein. (163 aa)
	smad7	Mothers against decapentaplegic homolog. (390 aa)
	ENSAMXP00000044530	Elastin microfibril interfacer 1b. (992 aa)
	ENSAMXP00000042872	Uncharacterized protein. (98 aa)
	LOC103023460	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	LOC103030936	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a. (265 aa)
	strap	Serine/threonine kinase receptor associated protein. (329 aa)
	ldlrad4	Low density lipoprotein receptor class A domain containing 4a. (311 aa)
	LOC103032076	Info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a. (566 aa)
	lemd3	LEM domain containing 3. (894 aa)
	LOC103028218	Golgi glycoprotein 1a. (1152 aa)
	LOC103031474	V-ski avian sarcoma viral oncogene homolog b. (964 aa)
	LOC103039852	Uncharacterized protein. (287 aa)
	LOC103029721	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b. (276 aa)
	LOC103047302	Leucine rich repeat and Ig domain containing 3a. (605 aa)
	spred3	Sprouty related EVH1 domain containing 3. (518 aa)
	bcl9l	Bcl9 like. (1520 aa)
	W5LF58_ASTMX	Uncharacterized protein. (512 aa)
	LOC103043623	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (173 aa)
	W5LD95_ASTMX	ADAM metallopeptidase domain 17a. (675 aa)
	LOC103024700	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2b. (561 aa)
	nrros	Negative regulator of reactive oxygen species. (683 aa)
	LOC103043091	Elastin microfibril interfacer 1a. (1050 aa)
	hspa5	Heat shock protein 5; Belongs to the heat shock protein 70 family. (654 aa)
	LOC103029205	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (181 aa)
	W5KFJ0_ASTMX	Mothers against decapentaplegic homolog. (468 aa)
	snx25	Sorting nexin 25. (963 aa)
	W5KCZ0_ASTMX	HtrA serine peptidase 3a. (454 aa)
	LOC103041996	ADAM metallopeptidase domain 17b. (841 aa)
	LOC103027845	SKI-like proto-oncogene b. (715 aa)
	Sirt1	Deacetylase sirtuin-type domain-containing protein. (802 aa)
	smad6	Mothers against decapentaplegic homolog. (480 aa)
	HTRA3	HtrA serine peptidase 3. (456 aa)
	tdp2	Tyrosyl-DNA phosphodiesterase 2b. (379 aa)
	pin1	Peptidyl-prolyl cis-trans isomerase. (158 aa)
	LOC103030012	Prostate transmembrane protein, androgen induced 1. (270 aa)
	prdm16	Si:ch211-263k4.2. (1302 aa)
	LOC103046211	V-ski avian sarcoma viral oncogene homolog a. (790 aa)
	Adamtsl2	ADAMTS-like 2. (923 aa)
	znf451	Zinc finger protein 451. (923 aa)
	LOC103029869	Ig-like domain-containing protein. (604 aa)
	LOC103040484	Uncharacterized protein. (287 aa)
	LOC103032663	Low density lipoprotein receptor class A domain containing 4b. (331 aa)
	skil	SKI-like proto-oncogene a. (681 aa)
	spry1	Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (359 aa)
	LOC103033610	Si:ch211-267e7.3. (968 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000042872	spry1	ENSAMXP00000042872	ENSAMXP00000047693	Uncharacterized protein.	Sprouty homolog 1, antagonist of FGF signaling (Drosophila).	0.646
LOC103027845	LOC103046211	ENSAMXP00000004340	ENSAMXP00000014512	SKI-like proto-oncogene b.	V-ski avian sarcoma viral oncogene homolog a.	0.604
LOC103027845	W5KFJ0_ASTMX	ENSAMXP00000004340	ENSAMXP00000006351	SKI-like proto-oncogene b.	Mothers against decapentaplegic homolog.	0.477
LOC103027845	smad6	ENSAMXP00000004340	ENSAMXP00000002954	SKI-like proto-oncogene b.	Mothers against decapentaplegic homolog.	0.477
LOC103027845	smad7	ENSAMXP00000004340	ENSAMXP00000051620	SKI-like proto-oncogene b.	Mothers against decapentaplegic homolog.	0.477
LOC103028218	LOC103038759	ENSAMXP00000033088	ENSAMXP00000048509	Golgi glycoprotein 1a.	Golgi glycoprotein 1b.	0.900
LOC103029721	LOC103030936	ENSAMXP00000027700	ENSAMXP00000037709	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b.	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a.	0.901
LOC103029721	W5KFJ0_ASTMX	ENSAMXP00000027700	ENSAMXP00000006351	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b.	Mothers against decapentaplegic homolog.	0.649
LOC103029721	smad6	ENSAMXP00000027700	ENSAMXP00000002954	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b.	Mothers against decapentaplegic homolog.	0.649
LOC103029721	smad7	ENSAMXP00000027700	ENSAMXP00000051620	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b.	Mothers against decapentaplegic homolog.	0.649
LOC103030936	LOC103029721	ENSAMXP00000037709	ENSAMXP00000027700	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a.	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b.	0.901
LOC103030936	W5KFJ0_ASTMX	ENSAMXP00000037709	ENSAMXP00000006351	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a.	Mothers against decapentaplegic homolog.	0.649
LOC103030936	smad6	ENSAMXP00000037709	ENSAMXP00000002954	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a.	Mothers against decapentaplegic homolog.	0.649
LOC103030936	smad7	ENSAMXP00000037709	ENSAMXP00000051620	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a.	Mothers against decapentaplegic homolog.	0.657
LOC103031474	W5KFJ0_ASTMX	ENSAMXP00000030947	ENSAMXP00000006351	V-ski avian sarcoma viral oncogene homolog b.	Mothers against decapentaplegic homolog.	0.422
LOC103031474	smad6	ENSAMXP00000030947	ENSAMXP00000002954	V-ski avian sarcoma viral oncogene homolog b.	Mothers against decapentaplegic homolog.	0.422
LOC103031474	smad7	ENSAMXP00000030947	ENSAMXP00000051620	V-ski avian sarcoma viral oncogene homolog b.	Mothers against decapentaplegic homolog.	0.422
LOC103038759	LOC103028218	ENSAMXP00000048509	ENSAMXP00000033088	Golgi glycoprotein 1b.	Golgi glycoprotein 1a.	0.900
LOC103039852	strap	ENSAMXP00000028589	ENSAMXP00000037425	Uncharacterized protein.	Serine/threonine kinase receptor associated protein.	0.558
LOC103040484	strap	ENSAMXP00000045496	ENSAMXP00000037425	Uncharacterized protein.	Serine/threonine kinase receptor associated protein.	0.558