45 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103030936	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a. (265 aa)
	LOC103032217	Dickkopf_N domain-containing protein. (277 aa)
	LOC103029280	SKI family transcriptional corepressor 1. (771 aa)
	smad6	Mothers against decapentaplegic homolog. (480 aa)
	LOC103027845	SKI-like proto-oncogene b. (715 aa)
	W5KCZ0_ASTMX	HtrA serine peptidase 3a. (454 aa)
	W5KFG3_ASTMX	SKI family transcriptional corepressor 1. (611 aa)
	W5KFJ0_ASTMX	Mothers against decapentaplegic homolog. (468 aa)
	tnfaip6	Tumor necrosis factor, alpha-induced protein 6. (264 aa)
	HTRA3	HtrA serine peptidase 3. (456 aa)
	LOC103024223	Secreted frizzled-related protein 2 like. (312 aa)
	chrd	Chordin; Belongs to the chordin family. (945 aa)
	LOC103046211	V-ski avian sarcoma viral oncogene homolog a. (790 aa)
	SMURF2	E3 ubiquitin-protein ligase. (761 aa)
	Spart	Spartin a. (559 aa)
	dkk1	Dickkopf WNT signaling pathway inhibitor 1b. (243 aa)
	W5LJ26_ASTMX	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2b. (445 aa)
	LOC103026512	Gremlin 2, DAN family BMP antagonist a. (195 aa)
	W5LU02_ASTMX	Gremlin. (175 aa)
	Grem2	Gremlin 2, DAN family BMP antagonist b. (166 aa)
	LOC103029721	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b. (276 aa)
	ENSAMXP00000028327	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 3. (365 aa)
	LOC103022941	RNA binding protein, mRNA processing factor 2b. (200 aa)
	ENSAMXP00000029564	Noggin 3. (201 aa)
	sfrp5	Secreted frizzled-related protein 5. (313 aa)
	LOC103031474	V-ski avian sarcoma viral oncogene homolog b. (964 aa)
	bmper	BMP binding endothelial regulator. (669 aa)
	lemd3	LEM domain containing 3. (894 aa)
	ENSAMXP00000035854	Noggin; Belongs to the noggin family. (209 aa)
	LOC103041046	Sclerostin domain containing 1b. (187 aa)
	LOC103044553	Gremlin 1a, DAN family BMP antagonist. (171 aa)
	smurf1	E3 ubiquitin-protein ligase. (731 aa)
	LOC103024839	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a. (470 aa)
	sostdc1	Sclerostin domain containing 1a. (227 aa)
	skor2	SKI family transcriptional corepressor 2. (758 aa)
	dlx6	Distal-less homeobox 6a. (247 aa)
	vwc2l	Von Willebrand factor C domain containing 2 like. (258 aa)
	skil	SKI-like proto-oncogene a. (681 aa)
	LOC103039147	Spartin b. (611 aa)
	LOC103026905	DAN domain family, member 5. (228 aa)
	ENSAMXP00000050414	E3 ubiquitin-protein ligase. (752 aa)
	ENSAMXP00000050565	Dickkopf WNT signaling pathway inhibitor 1a. (277 aa)
	smad7	Mothers against decapentaplegic homolog. (390 aa)
	chrdl2	Chordin-like 2. (452 aa)
	fstl3	Follistatin-like 3 (secreted glycoprotein). (244 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000029564	LOC103024223	ENSAMXP00000029564	ENSAMXP00000011888	Noggin 3.	Secreted frizzled-related protein 2 like.	0.435
ENSAMXP00000029564	chrd	ENSAMXP00000029564	ENSAMXP00000012078	Noggin 3.	Chordin; Belongs to the chordin family.	0.497
ENSAMXP00000035854	LOC103024223	ENSAMXP00000035854	ENSAMXP00000011888	Noggin; Belongs to the noggin family.	Secreted frizzled-related protein 2 like.	0.435
ENSAMXP00000035854	bmper	ENSAMXP00000035854	ENSAMXP00000033813	Noggin; Belongs to the noggin family.	BMP binding endothelial regulator.	0.414
ENSAMXP00000035854	chrd	ENSAMXP00000035854	ENSAMXP00000012078	Noggin; Belongs to the noggin family.	Chordin; Belongs to the chordin family.	0.580
ENSAMXP00000050414	W5KFJ0_ASTMX	ENSAMXP00000050414	ENSAMXP00000006351	E3 ubiquitin-protein ligase.	Mothers against decapentaplegic homolog.	0.829
ENSAMXP00000050414	smad6	ENSAMXP00000050414	ENSAMXP00000002954	E3 ubiquitin-protein ligase.	Mothers against decapentaplegic homolog.	0.829
ENSAMXP00000050414	smad7	ENSAMXP00000050414	ENSAMXP00000051620	E3 ubiquitin-protein ligase.	Mothers against decapentaplegic homolog.	0.904
ENSAMXP00000050565	LOC103024223	ENSAMXP00000050565	ENSAMXP00000011888	Dickkopf WNT signaling pathway inhibitor 1a.	Secreted frizzled-related protein 2 like.	0.422
Grem2	LOC103026512	ENSAMXP00000026726	ENSAMXP00000026122	Gremlin 2, DAN family BMP antagonist b.	Gremlin 2, DAN family BMP antagonist a.	0.903
Grem2	LOC103026905	ENSAMXP00000026726	ENSAMXP00000049022	Gremlin 2, DAN family BMP antagonist b.	DAN domain family, member 5.	0.443
Grem2	LOC103044553	ENSAMXP00000026726	ENSAMXP00000040295	Gremlin 2, DAN family BMP antagonist b.	Gremlin 1a, DAN family BMP antagonist.	0.905
Grem2	chrd	ENSAMXP00000026726	ENSAMXP00000012078	Gremlin 2, DAN family BMP antagonist b.	Chordin; Belongs to the chordin family.	0.515
LOC103024223	ENSAMXP00000029564	ENSAMXP00000011888	ENSAMXP00000029564	Secreted frizzled-related protein 2 like.	Noggin 3.	0.435
LOC103024223	ENSAMXP00000035854	ENSAMXP00000011888	ENSAMXP00000035854	Secreted frizzled-related protein 2 like.	Noggin; Belongs to the noggin family.	0.435
LOC103024223	ENSAMXP00000050565	ENSAMXP00000011888	ENSAMXP00000050565	Secreted frizzled-related protein 2 like.	Dickkopf WNT signaling pathway inhibitor 1a.	0.422
LOC103024223	LOC103032217	ENSAMXP00000011888	ENSAMXP00000002252	Secreted frizzled-related protein 2 like.	Dickkopf_N domain-containing protein.	0.422
LOC103024223	dkk1	ENSAMXP00000011888	ENSAMXP00000018708	Secreted frizzled-related protein 2 like.	Dickkopf WNT signaling pathway inhibitor 1b.	0.422
LOC103026512	Grem2	ENSAMXP00000026122	ENSAMXP00000026726	Gremlin 2, DAN family BMP antagonist a.	Gremlin 2, DAN family BMP antagonist b.	0.903
LOC103026512	LOC103044553	ENSAMXP00000026122	ENSAMXP00000040295	Gremlin 2, DAN family BMP antagonist a.	Gremlin 1a, DAN family BMP antagonist.	0.905