(8 nodes) HOPS complex network (Astyanax mexicanus)

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	Vps11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (946 aa)
	stx17	Syntaxin 17; Belongs to the syntaxin family. (297 aa)
	vps39	VPS39 subunit of HOPS complex. (875 aa)
	vps18	VPS18 core subunit of CORVET and HOPS complexes. (978 aa)
	hook2	Hook microtubule-tethering protein 2. (709 aa)
	vps33a	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. (600 aa)
	W5KC71_ASTMX	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (801 aa)
	vps41	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Vps11	W5KC71_ASTMX	ENSAMXP00000004514	ENSAMXP00000005182	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.997
Vps11	stx17	ENSAMXP00000004514	ENSAMXP00000053022	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	Syntaxin 17; Belongs to the syntaxin family.	0.792
Vps11	vps18	ENSAMXP00000004514	ENSAMXP00000017763	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	VPS18 core subunit of CORVET and HOPS complexes.	0.999
Vps11	vps33a	ENSAMXP00000004514	ENSAMXP00000014081	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.	0.997
Vps11	vps39	ENSAMXP00000004514	ENSAMXP00000048859	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	VPS39 subunit of HOPS complex.	0.999
Vps11	vps41	ENSAMXP00000004514	ENSAMXP00000002952	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.999
W5KC71_ASTMX	Vps11	ENSAMXP00000005182	ENSAMXP00000004514	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	0.997
W5KC71_ASTMX	stx17	ENSAMXP00000005182	ENSAMXP00000053022	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Syntaxin 17; Belongs to the syntaxin family.	0.806
W5KC71_ASTMX	vps18	ENSAMXP00000005182	ENSAMXP00000017763	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	VPS18 core subunit of CORVET and HOPS complexes.	0.997
W5KC71_ASTMX	vps33a	ENSAMXP00000005182	ENSAMXP00000014081	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.	0.997
W5KC71_ASTMX	vps39	ENSAMXP00000005182	ENSAMXP00000048859	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	VPS39 subunit of HOPS complex.	0.997
W5KC71_ASTMX	vps41	ENSAMXP00000005182	ENSAMXP00000002952	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.997
stx17	Vps11	ENSAMXP00000053022	ENSAMXP00000004514	Syntaxin 17; Belongs to the syntaxin family.	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	0.792
stx17	W5KC71_ASTMX	ENSAMXP00000053022	ENSAMXP00000005182	Syntaxin 17; Belongs to the syntaxin family.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.806
stx17	vps18	ENSAMXP00000053022	ENSAMXP00000017763	Syntaxin 17; Belongs to the syntaxin family.	VPS18 core subunit of CORVET and HOPS complexes.	0.739
stx17	vps33a	ENSAMXP00000053022	ENSAMXP00000014081	Syntaxin 17; Belongs to the syntaxin family.	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.	0.743
stx17	vps39	ENSAMXP00000053022	ENSAMXP00000048859	Syntaxin 17; Belongs to the syntaxin family.	VPS39 subunit of HOPS complex.	0.964
stx17	vps41	ENSAMXP00000053022	ENSAMXP00000002952	Syntaxin 17; Belongs to the syntaxin family.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.935
vps18	Vps11	ENSAMXP00000017763	ENSAMXP00000004514	VPS18 core subunit of CORVET and HOPS complexes.	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	0.999
vps18	W5KC71_ASTMX	ENSAMXP00000017763	ENSAMXP00000005182	VPS18 core subunit of CORVET and HOPS complexes.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.997