77 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAMXP00000047894	Endothelin 1. (162 aa)
	LOC103021856	Bone morphogenetic protein 2a. (405 aa)
	sema3d	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (787 aa)
	W5K0L4_ASTMX	MADS-box domain-containing protein. (479 aa)
	vwa5b2	Von Willebrand factor A domain containing 5B2. (1328 aa)
	NOX4	NADPH oxidase 4. (481 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
	LOC103047227	Uncharacterized protein. (573 aa)
	Alpk2	Uncharacterized protein. (2658 aa)
	W5KMM6_ASTMX	TSC complex subunit 1b. (1211 aa)
	cby1	Chibby homolog 1 (Drosophila). (125 aa)
	Tbx5	T-box transcription factor 5a. (522 aa)
	W5KQ23_ASTMX	Patched 2. (1330 aa)
	TBX10	T-box transcription factor 10. (196 aa)
	LOC103044660	Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (492 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2518 aa)
	LOC103042002	Ankyrin repeat and SOCS box containing 2b. (619 aa)
	W5L5P0_ASTMX	Nebulin-related anchoring protein. (1418 aa)
	LOC103042940	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (425 aa)
	tsc1	TSC complex subunit 1a. (1148 aa)
	W5LD66_ASTMX	Mothers against decapentaplegic homolog. (573 aa)
	LOC103021321	SRY-box transcription factor 17. (428 aa)
	LOC103022359	Mothers against decapentaplegic homolog. (587 aa)
	LOC103029394	Mothers against decapentaplegic homolog. (544 aa)
	W5LMI9_ASTMX	T-box transcription factor 1. (417 aa)
	LOC103043805	Myocyte enhancer factor 2ab. (472 aa)
	Lrrc10	Leucine rich repeat containing 10. (282 aa)
	LOC103026512	Gremlin 2, DAN family BMP antagonist a. (195 aa)
	W5LU02_ASTMX	Gremlin. (175 aa)
	LRRC10B	Leucine rich repeat containing 10B. (266 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (429 aa)
	ENSAMXP00000028486	Mothers against decapentaplegic homolog. (493 aa)
	LOC103025318	NK2 homeobox 5. (313 aa)
	SRF	Serum response factor. (527 aa)
	ENSAMXP00000030497	Myocyte enhancer factor 2ca. (397 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (903 aa)
	LOC107197257	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (451 aa)
	hand2	Heart and neural crest derivatives expressed 2. (200 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	ENSAMXP00000033131	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (475 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (470 aa)
	ENSAMXP00000033496	Cysteine and glycine-rich protein 3 (cardiac LIM protein). (182 aa)
	ENSAMXP00000033502	Uncharacterized protein. (387 aa)
	ENSAMXP00000035294	Uncharacterized protein. (1391 aa)
	Mef2c	Myocyte enhancer factor 2cb. (471 aa)
	LOC103028976	Bone morphogenetic protein 2b. (445 aa)
	maml1	Mastermind-like transcriptional coactivator 1. (1070 aa)
	LOC103028490	Lysine (K)-specific demethylase 6B, b. (1798 aa)
	LOC103032897	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
	Sox18	SRY-box transcription factor 18. (470 aa)
	LOC103029324	Bone morphogenetic protein 16. (430 aa)
	ENSAMXP00000037899	MADS-box domain-containing protein. (356 aa)
	MYOCD	Myocardin. (999 aa)
	opa1	OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (982 aa)
	LOC103033204	Si:dkey-49n23.1; Belongs to the semaphorin family. (752 aa)
	LOC103021841	Islet1, like. (328 aa)
	LOC103043375	Titin-cap (telethonin). (179 aa)
	ENSAMXP00000042035	Myosin light chain kinase 3. (536 aa)
	LOC103041704	Ankyrin repeat and SOCS box containing 2a, tandem duplicate 1. (686 aa)
	sirt6	Sirtuin 6. (396 aa)
	alpk3	Uncharacterized protein. (1821 aa)
	irx3	Iroquois homeobox 3b. (361 aa)
	nkx2-6	Homeobox domain-containing protein. (294 aa)
	W5K9M8_ASTMX	Uncharacterized protein. (174 aa)
	mef2a	Myocyte enhancer factor 2aa. (517 aa)
	bmp4	TGF_BETA_2 domain-containing protein. (481 aa)
	tbx3	T-box transcription factor 3a. (706 aa)
	kdm6b	Lysine (K)-specific demethylase 6B, a. (1983 aa)
	LOC103030680	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. (898 aa)
	ENSAMXP00000047021	Ankyrin repeat and SOCS box containing 2a, tandem duplicate 1. (658 aa)
	acadm	Acyl-CoA dehydrogenase medium chain. (422 aa)
	isl1	ISL LIM homeobox 1. (332 aa)
	map2k4	Mitogen-activated protein kinase kinase 4a; Belongs to the protein kinase superfamily. (422 aa)
	LOC107197240	BHLH domain-containing protein. (244 aa)
	Adprhl1	ADP-ribosylhydrolase like 1. (301 aa)
	LOC103042476	Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
	ENSAMXP00000053345	MH1 domain-containing protein. (187 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2	LOC103030680	ENSAMXP00000031306	ENSAMXP00000046775	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins.	0.901
ENSAMXP00000028486	LOC103021856	ENSAMXP00000028486	ENSAMXP00000000963	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 2a.	0.633
ENSAMXP00000028486	LOC103028976	ENSAMXP00000028486	ENSAMXP00000035663	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 2b.	0.633
ENSAMXP00000028486	LOC103029324	ENSAMXP00000028486	ENSAMXP00000037650	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 16.	0.633
ENSAMXP00000028486	LOC103042476	ENSAMXP00000028486	ENSAMXP00000051642	Mothers against decapentaplegic homolog.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.427
ENSAMXP00000028486	bmp4	ENSAMXP00000028486	ENSAMXP00000046234	Mothers against decapentaplegic homolog.	TGF_BETA_2 domain-containing protein.	0.706
ENSAMXP00000030497	LOC103021841	ENSAMXP00000030497	ENSAMXP00000040473	Myocyte enhancer factor 2ca.	Islet1, like.	0.410
ENSAMXP00000030497	LOC103025318	ENSAMXP00000030497	ENSAMXP00000028592	Myocyte enhancer factor 2ca.	NK2 homeobox 5.	0.809
ENSAMXP00000030497	Tbx5	ENSAMXP00000030497	ENSAMXP00000009448	Myocyte enhancer factor 2ca.	T-box transcription factor 5a.	0.659
ENSAMXP00000030497	hand2	ENSAMXP00000030497	ENSAMXP00000032184	Myocyte enhancer factor 2ca.	Heart and neural crest derivatives expressed 2.	0.577
ENSAMXP00000030497	isl1	ENSAMXP00000030497	ENSAMXP00000048720	Myocyte enhancer factor 2ca.	ISL LIM homeobox 1.	0.410
ENSAMXP00000030497	nkx2-6	ENSAMXP00000030497	ENSAMXP00000044271	Myocyte enhancer factor 2ca.	Homeobox domain-containing protein.	0.583
ENSAMXP00000033131	ENSAMXP00000047894	ENSAMXP00000033131	ENSAMXP00000047894	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.978
ENSAMXP00000033131	LOC107197257	ENSAMXP00000033131	ENSAMXP00000032052	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.902
ENSAMXP00000033496	ENSAMXP00000035294	ENSAMXP00000033496	ENSAMXP00000035294	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	Uncharacterized protein.	0.433
ENSAMXP00000033496	LOC103043375	ENSAMXP00000033496	ENSAMXP00000040530	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	Titin-cap (telethonin).	0.719
ENSAMXP00000033496	W5L5P0_ASTMX	ENSAMXP00000033496	ENSAMXP00000015152	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	Nebulin-related anchoring protein.	0.612
ENSAMXP00000033502	LOC103043375	ENSAMXP00000033502	ENSAMXP00000040530	Uncharacterized protein.	Titin-cap (telethonin).	0.519
ENSAMXP00000033502	W5L5P0_ASTMX	ENSAMXP00000033502	ENSAMXP00000015152	Uncharacterized protein.	Nebulin-related anchoring protein.	0.406
ENSAMXP00000035294	ENSAMXP00000033496	ENSAMXP00000035294	ENSAMXP00000033496	Uncharacterized protein.	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	0.433