STRINGSTRING
LOC103030495 LOC103030495 cftr cftr ncoa2 ncoa2 LOC103024888 LOC103024888 Hdac9 Hdac9 W5KF46_ASTMX W5KF46_ASTMX hoxd4 hoxd4 etnppl etnppl chrd chrd LOC103025973 LOC103025973 W5L6U8_ASTMX W5L6U8_ASTMX W5L798_ASTMX W5L798_ASTMX W5L9B7_ASTMX W5L9B7_ASTMX LOC103031807 LOC103031807 tgfbr2 tgfbr2 LOC103045069 LOC103045069 LOC103039499 LOC103039499 LOC103045279 LOC103045279 lmo2 lmo2 med1 med1 ENSAMXP00000032410 ENSAMXP00000032410 phf8 phf8 ENSAMXP00000033395 ENSAMXP00000033395 bmi1 bmi1 nop10 nop10 atf4 atf4 slc40a1 slc40a1 trim33 trim33 Lclat1 Lclat1 Tll1 Tll1 LOC103042559 LOC103042559 prkcb prkcb ENSAMXP00000045222 ENSAMXP00000045222 LOC103047782 LOC103047782 ENSAMXP00000051081 ENSAMXP00000051081 slc25a37 slc25a37 LOC103044058 LOC103044058 Ccdc134 Ccdc134 tbx20 tbx20 Tal1 Tal1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103030495Histone deacetylase 9b. (615 aa)
cftrCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1486 aa)
ncoa2Nuclear receptor coactivator. (1502 aa)
LOC103024888Metalloendopeptidase. (976 aa)
Hdac9Uncharacterized protein. (412 aa)
W5KF46_ASTMXTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (561 aa)
hoxd4Homeobox D4a. (256 aa)
etnpplEthanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (490 aa)
chrdChordin; Belongs to the chordin family. (945 aa)
LOC103025973Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
W5L6U8_ASTMXProtein kinase C. (646 aa)
W5L798_ASTMXYes-associated protein 1. (431 aa)
W5L9B7_ASTMXProtein kinase C, gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1262 aa)
LOC103031807Uncharacterized protein. (427 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
LOC103045069Metalloendopeptidase. (1044 aa)
LOC103039499Uncharacterized protein. (686 aa)
LOC103045279Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
lmo2LIM domain only 2 (rhombotin-like 1). (159 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1801 aa)
ENSAMXP00000032410SH2B adaptor protein 3. (520 aa)
phf8PHD finger protein 8. (1046 aa)
ENSAMXP00000033395GATA binding protein 1a. (372 aa)
bmi1Bmi1 polycomb ring finger oncogene 1a. (324 aa)
nop10NOP10 ribonucleoprotein homolog (yeast). (64 aa)
atf4Activating transcription factor 4a. (398 aa)
slc40a1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (567 aa)
trim33Tripartite motif containing 33. (1251 aa)
Lclat1Lysocardiolipin acyltransferase 1. (364 aa)
Tll1Metalloendopeptidase. (1022 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
prkcbProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
ENSAMXP00000045222Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (581 aa)
LOC1030477825-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
ENSAMXP00000051081AGC-kinase C-terminal domain-containing protein. (50 aa)
slc25a37Solute carrier family 25 member 37; Belongs to the mitochondrial carrier (TC 2.A.29) family. (338 aa)
LOC103044058Myc target 1a. (212 aa)
Ccdc134Si:dkey-167k11.5. (224 aa)
tbx20T-box transcription factor 20. (441 aa)
Tal1T-cell acute lymphocytic leukemia 1. (371 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (12%) [HD]