(12 nodes) Dorsal aorta development network (Astyanax mexicanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hey2	Hes-related family bHLH transcription factor with YRPW motif 2. (315 aa)
	Dll3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (708 aa)
	ENSAMXP00000045776	Nerve growth factor receptor a (TNFR superfamily, member 16). (419 aa)
	LOC103035447	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (265 aa)
	ENSAMXP00000037899	MADS-box domain-containing protein. (356 aa)
	nkx3-1	NK3 homeobox 1. (202 aa)
	SRF	Serum response factor. (527 aa)
	LOC103037702	Angiomotin like 2b. (692 aa)
	LOC103034623	Notch receptor 1a. (2450 aa)
	amotl2	Angiomotin like 2a. (735 aa)
	W5K0L4_ASTMX	MADS-box domain-containing protein. (479 aa)
	LOC103025197	Notch receptor 1b. (2477 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Dll3	LOC103025197	ENSAMXP00000050702	ENSAMXP00000051793	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1b.	0.976
Dll3	LOC103034623	ENSAMXP00000050702	ENSAMXP00000015021	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1a.	0.976
ENSAMXP00000045776	LOC103035447	ENSAMXP00000045776	ENSAMXP00000040217	Nerve growth factor receptor a (TNFR superfamily, member 16).	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family.	0.688
LOC103025197	Dll3	ENSAMXP00000051793	ENSAMXP00000050702	Notch receptor 1b.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.976
LOC103025197	hey2	ENSAMXP00000051793	ENSAMXP00000049413	Notch receptor 1b.	Hes-related family bHLH transcription factor with YRPW motif 2.	0.476
LOC103034623	Dll3	ENSAMXP00000015021	ENSAMXP00000050702	Notch receptor 1a.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.976
LOC103034623	hey2	ENSAMXP00000015021	ENSAMXP00000049413	Notch receptor 1a.	Hes-related family bHLH transcription factor with YRPW motif 2.	0.476
LOC103035447	ENSAMXP00000045776	ENSAMXP00000040217	ENSAMXP00000045776	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family.	Nerve growth factor receptor a (TNFR superfamily, member 16).	0.688
hey2	LOC103025197	ENSAMXP00000049413	ENSAMXP00000051793	Hes-related family bHLH transcription factor with YRPW motif 2.	Notch receptor 1b.	0.476
hey2	LOC103034623	ENSAMXP00000049413	ENSAMXP00000015021	Hes-related family bHLH transcription factor with YRPW motif 2.	Notch receptor 1a.	0.476