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plcg2 plcg2 LOC103036711 LOC103036711 LOC103023882 LOC103023882 W5K623_ASTMX W5K623_ASTMX W5K912_ASTMX W5K912_ASTMX W5K9D0_ASTMX W5K9D0_ASTMX W5K9G5_ASTMX W5K9G5_ASTMX LOC103037777 LOC103037777 Pla2g6 Pla2g6 W5KCE6_ASTMX W5KCE6_ASTMX Bax Bax stim1 stim1 snx4 snx4 LOC103043075 LOC103043075 LOC103047816 LOC103047816 Akap6 Akap6 ace2 ace2 LOC103022345 LOC103022345 Htt Htt stim2 stim2 LOC103023526 LOC103023526 Lrrc38 Lrrc38 R3HDM1 R3HDM1 cdk5 cdk5 W5L1R1_ASTMX W5L1R1_ASTMX RELN RELN p2rx1 p2rx1 W5LD01_ASTMX W5LD01_ASTMX atpsckmt atpsckmt W5LK17_ASTMX W5LK17_ASTMX W5LM01_ASTMX W5LM01_ASTMX arpp21 arpp21 LOC103031227 LOC103031227 Wnk4 Wnk4 f2 f2 rnf207 rnf207 LOC103025241 LOC103025241 W5LRS6_ASTMX W5LRS6_ASTMX W5LSB9_ASTMX W5LSB9_ASTMX LOC103030072 LOC103030072 amigo3 amigo3 LOC103047191 LOC103047191 amigo1 amigo1 LOC103044601 LOC103044601 Tesc Tesc LOC103025318 LOC103025318 ENSAMXP00000028704 ENSAMXP00000028704 LOC103033732 LOC103033732 fhl1 fhl1 cxcr3 cxcr3 Cask Cask LOC103033291 LOC103033291 apopt1 apopt1 ENSAMXP00000030762 ENSAMXP00000030762 Tmem27 Tmem27 RNF207 RNF207 LOC107197257 LOC107197257 plcg1 plcg1 ENSAMXP00000033131 ENSAMXP00000033131 LOC103042184 LOC103042184 LOC103032641 LOC103032641 ENSAMXP00000035483 ENSAMXP00000035483 LOC103028784 LOC103028784 LOC103027401 LOC103027401 ENSAMXP00000037024 ENSAMXP00000037024 ENSAMXP00000038137 ENSAMXP00000038137 P2rx4 P2rx4 LOC103023460 LOC103023460 ENSAMXP00000038960 ENSAMXP00000038960 ENSAMXP00000039292 ENSAMXP00000039292 Stac Stac LOC103032814 LOC103032814 STAC3 STAC3 stc1 stc1 LOC103046346 LOC103046346 F2R F2R drd4 drd4 pink1 pink1 f2r f2r ENSAMXP00000041831 ENSAMXP00000041831 ENSAMXP00000041912 ENSAMXP00000041912 ENSAMXP00000041969 ENSAMXP00000041969 ENSAMXP00000042325 ENSAMXP00000042325 HOMER1 HOMER1 ENSAMXP00000042655 ENSAMXP00000042655 LOC103025099 LOC103025099 LOC103040208 LOC103040208 scn3b scn3b LOC103044362 LOC103044362 LOC103031467 LOC103031467 LOC103038802 LOC103038802 RAMP3 RAMP3 r3hdm1 r3hdm1 LOC103025686 LOC103025686 LOC103031161 LOC103031161 LOC103038069 LOC103038069 ENSAMXP00000045644 ENSAMXP00000045644 chp1 chp1 trpc1 trpc1 LOC103039925 LOC103039925 LOC103036582 LOC103036582 ucn ucn kcnq1 kcnq1 trh trh ENSAMXP00000046835 ENSAMXP00000046835 LOC103029856 LOC103029856 LOC103038317 LOC103038317 ENSAMXP00000047894 ENSAMXP00000047894 LOC103040268 LOC103040268 STAC2 STAC2 ENSAMXP00000048966 ENSAMXP00000048966 ENSAMXP00000049531 ENSAMXP00000049531 ENSAMXP00000049817 ENSAMXP00000049817 LOC103038583 LOC103038583 pdzk1 pdzk1 LOC103040974 LOC103040974 ENSAMXP00000052402 ENSAMXP00000052402 LOC103035732 LOC103035732 ptges ptges ENSAMXP00000053021 ENSAMXP00000053021 scn4b scn4b AKAP7 AKAP7 ENSAMXP00000054945 ENSAMXP00000054945
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
LOC103036711Vesicle-associated membrane protein 8 (endobrevin). (127 aa)
LOC103023882Sodium channel, voltage-gated, type IV, beta b. (226 aa)
W5K623_ASTMXNADH:ubiquinone oxidoreductase subunit A4, like. (83 aa)
W5K912_ASTMXWolfram syndrome 1a (wolframin). (542 aa)
W5K9D0_ASTMXP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (382 aa)
W5K9G5_ASTMXGalectin. (263 aa)
LOC103037777Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (528 aa)
Pla2g6Phospholipase A2, group VI (cytosolic, calcium-independent). (822 aa)
W5KCE6_ASTMXSi:dkey-52j6.3. (327 aa)
BaxBCL2 associated X, apoptosis regulator a. (190 aa)
stim1Stromal interaction molecule 1b. (674 aa)
snx4Sorting nexin 4. (436 aa)
LOC103043075Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (285 aa)
LOC103047816Zgc:153993. (204 aa)
Akap6Uncharacterized protein. (728 aa)
ace2Angiotensin-converting enzyme. (805 aa)
LOC103022345Calcineurin-like EF-hand protein 2. (194 aa)
HttHuntingtin. (3069 aa)
stim2Stromal interaction molecule 2b. (708 aa)
LOC103023526NADH:ubiquinone oxidoreductase subunit A4. (82 aa)
Lrrc38Leucine rich repeat containing 38b. (290 aa)
R3HDM1R3H domain containing 1. (1126 aa)
cdk5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
W5L1R1_ASTMXCalcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (854 aa)
RELNReelin. (3447 aa)
p2rx1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (393 aa)
W5LD01_ASTMXR3H domain containing 2. (889 aa)
atpsckmtFATP synthase c subunit lysine N-methyltransferase. (235 aa)
W5LK17_ASTMXP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (472 aa)
W5LM01_ASTMXSolute carrier family 17 member 8. (590 aa)
arpp21cAMP-regulated phosphoprotein, 21. (689 aa)
LOC103031227ORAI calcium release-activated calcium modulator 1b. (217 aa)
Wnk4Protein kinase domain-containing protein. (437 aa)
f2Coagulation factor II (thrombin); Belongs to the peptidase S1 family. (619 aa)
rnf207Ring finger protein 207b. (640 aa)
LOC103025241Apelin receptor a; Belongs to the G-protein coupled receptor 1 family. (359 aa)
W5LRS6_ASTMXSi:dkey-211g8.9. (268 aa)
W5LSB9_ASTMXApelin receptor b; Belongs to the G-protein coupled receptor 1 family. (364 aa)
LOC103030072G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (362 aa)
amigo3Adhesion molecule with Ig-like domain 3. (457 aa)
LOC103047191Purinergic receptor P2Y12. (350 aa)
amigo1Adhesion molecule with Ig-like domain 1. (495 aa)
LOC103044601Leucine rich repeat containing 38a. (291 aa)
TescTescalcin a. (203 aa)
LOC103025318NK2 homeobox 5. (313 aa)
ENSAMXP00000028704Galectin. (93 aa)
LOC103033732Galectin. (250 aa)
fhl1Four and a half LIM domains 1a. (297 aa)
cxcr3Chemokine (C-X-C motif) receptor 3, tandem duplicate 1; Belongs to the G-protein coupled receptor 1 family. (362 aa)
CaskCalcium/calmodulin-dependent serine protein kinase a; Belongs to the MAGUK family. (886 aa)
LOC103033291F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (397 aa)
apopt1Cytochrome c oxidase assembly factor 8. (195 aa)
ENSAMXP00000030762Stromal interaction molecule 1a. (751 aa)
Tmem27Si:dkey-194e6.1. (235 aa)
RNF207Ring finger protein 207. (746 aa)
LOC107197257Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (451 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1307 aa)
ENSAMXP00000033131G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (475 aa)
LOC103042184Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (335 aa)
LOC103032641Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (526 aa)
ENSAMXP00000035483G_PROTEIN_RECEP_F1_2 domain-containing protein. (355 aa)
LOC103028784Potassium voltage-gated channel, KQT-like subfamily, member 1.2; Belongs to the potassium channel family. (734 aa)
LOC103027401Uncharacterized protein. (275 aa)
ENSAMXP00000037024Uncharacterized protein. (1347 aa)
ENSAMXP00000038137Dopamine receptor D4b; Belongs to the G-protein coupled receptor 1 family. (376 aa)
P2rx4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (510 aa)
LOC103023460Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
ENSAMXP00000038960Uncharacterized protein. (124 aa)
ENSAMXP00000039292G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (347 aa)
StacSH3 and cysteine rich domain. (361 aa)
LOC103032814Four and a half LIM domains 1b. (340 aa)
STAC3SH3 and cysteine rich domain 3. (344 aa)
stc1Stanniocalcin 1. (250 aa)
LOC103046346Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
F2RG_PROTEIN_RECEP_F1_2 domain-containing protein. (471 aa)
drd4Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (387 aa)
pink1PTEN induced kinase 1. (571 aa)
f2rCoagulation factor II (thrombin) receptor. (414 aa)
ENSAMXP00000041831Cytochrome c oxidase copper chaperone COX17. (105 aa)
ENSAMXP00000041912Tescalcin b. (217 aa)
ENSAMXP00000041969Uncharacterized protein. (261 aa)
ENSAMXP00000042325Uncharacterized protein. (132 aa)
HOMER1Homer scaffold protein 1. (371 aa)
ENSAMXP00000042655Ig-like domain-containing protein. (492 aa)
LOC103025099Galectin. (379 aa)
LOC103040208Homer scaffold protein 1b. (398 aa)
scn3bSodium channel, voltage-gated, type III, beta. (223 aa)
LOC103044362Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (276 aa)
LOC103031467Sorcin. (191 aa)
LOC103038802Protein kinase domain-containing protein. (1685 aa)
RAMP3Receptor activity modifying protein 3. (96 aa)
r3hdm1R3H domain containing 1. (1140 aa)
LOC103025686G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (439 aa)
LOC103031161Tromal interaction molecule 2a. (1019 aa)
LOC103038069Wolfram syndrome 1b (wolframin). (908 aa)
ENSAMXP00000045644Protein kinase domain-containing protein. (377 aa)
chp1Calcineurin-like EF-hand protein 1. (194 aa)
trpc1Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family. (798 aa)
LOC103039925Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (335 aa)
LOC103036582WNK lysine deficient protein kinase 4b. (1614 aa)
ucnUrotensin 1. (207 aa)
kcnq1Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (662 aa)
trhPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (241 aa)
ENSAMXP00000046835Si:dkey-190g11.3. (207 aa)
LOC103029856Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (324 aa)
LOC103038317WNK lysine deficient protein kinase 2. (2670 aa)
ENSAMXP00000047894Endothelin 1. (162 aa)
LOC103040268Uncharacterized protein. (231 aa)
STAC2SH3 and cysteine rich domain 2. (377 aa)
ENSAMXP00000048966WNK lysine deficient protein kinase 2. (2447 aa)
ENSAMXP00000049531Uncharacterized protein. (223 aa)
ENSAMXP00000049817TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (165 aa)
LOC103038583Tumor necrosis factor receptor superfamily, member 11a, NFKB activator. (582 aa)
pdzk1PDZ domain containing 1. (574 aa)
LOC103040974Phospholipase A(2). (153 aa)
ENSAMXP00000052402TNF superfamily member 11; Belongs to the tumor necrosis factor family. (231 aa)
LOC103035732Galectin. (363 aa)
ptgesProstaglandin E synthase. (146 aa)
ENSAMXP00000053021WNK lysine deficient protein kinase 1b. (2468 aa)
scn4bSodium channel, voltage-gated, type IV, beta a. (233 aa)
AKAP7A-kinase anchoring protein 7. (444 aa)
ENSAMXP00000054945Uncharacterized protein. (171 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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