STRINGSTRING
kit kit axin1 axin1 ajuba ajuba NOX4 NOX4 pik3cg pik3cg LOC103037777 LOC103037777 LOC103041009 LOC103041009 pdcd10 pdcd10 LOC103038186 LOC103038186 LOC103043145 LOC103043145 LOC103024607 LOC103024607 LOC103030717 LOC103030717 W5KZR6_ASTMX W5KZR6_ASTMX LOC103035431 LOC103035431 TENM1 TENM1 LOC103022197 LOC103022197 map3k7 map3k7 W5L834_ASTMX W5L834_ASTMX Lrrk2 Lrrk2 tpd52l1 tpd52l1 W5LFM7_ASTMX W5LFM7_ASTMX dkk1 dkk1 W5LGF4_ASTMX W5LGF4_ASTMX Fzd5 Fzd5 pdgfc pdgfc ENSAMXP00000030711 ENSAMXP00000030711 il34 il34 PTPRC PTPRC LOC103036474 LOC103036474 LOC103027348 LOC103027348 LOC103044392 LOC103044392 LOC103032641 LOC103032641 LOC107197829 LOC107197829 ENSAMXP00000036986 ENSAMXP00000036986 ENSAMXP00000038137 ENSAMXP00000038137 fgf2 fgf2 epgn epgn map2k5 map2k5 LOC111190374 LOC111190374 drd4 drd4 ENSAMXP00000041061 ENSAMXP00000041061 pik3r5 pik3r5 ENSAMXP00000042552 ENSAMXP00000042552 LOC103038135 LOC103038135 LOC111194997 LOC111194997 LOC103044858 LOC103044858 LOC103025686 LOC103025686 ENSAMXP00000045985 ENSAMXP00000045985 ENSAMXP00000046425 ENSAMXP00000046425 ENSAMXP00000047619 ENSAMXP00000047619 ENSAMXP00000047894 ENSAMXP00000047894 LOC103029481 LOC103029481 LOC103046764 LOC103046764 ENSAMXP00000049295 ENSAMXP00000049295 ENSAMXP00000049817 ENSAMXP00000049817 sash1 sash1 ENSAMXP00000050565 ENSAMXP00000050565 LOC103038583 LOC103038583 ENSAMXP00000052402 ENSAMXP00000052402 tgfb2 tgfb2 ENSAMXP00000053072 ENSAMXP00000053072 map3k13 map3k13 ENSAMXP00000055082 ENSAMXP00000055082 W5K095_ASTMX W5K095_ASTMX Htr2b Htr2b LOC103032217 LOC103032217 tgfb1 tgfb1 fzd4 fzd4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
kitMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (974 aa)
axin1Axin 1. (866 aa)
ajubaAjuba LIM protein. (691 aa)
NOX4NADPH oxidase 4. (481 aa)
pik3cgPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1105 aa)
LOC103037777Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (528 aa)
LOC103041009Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
pdcd10Programmed cell death 10b. (210 aa)
LOC103038186Teneurin transmembrane protein 1. (2718 aa)
LOC103043145Dual specificity phosphatase 19b; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (198 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
LOC103030717Uncharacterized protein. (750 aa)
W5KZR6_ASTMXProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (343 aa)
LOC103035431Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family. (1085 aa)
TENM1Teneurin transmembrane protein 1. (2670 aa)
LOC103022197Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (202 aa)
map3k7Mitogen-activated protein kinase kinase kinase 7. (605 aa)
W5L834_ASTMXFibroblast growth factor receptor. (735 aa)
Lrrk2Leucine-rich repeat kinase 2. (2537 aa)
tpd52l1Tpd52 like 1. (227 aa)
W5LFM7_ASTMXMitogen-activated protein kinase kinase kinase 4. (1473 aa)
dkk1Dickkopf WNT signaling pathway inhibitor 1b. (243 aa)
W5LGF4_ASTMXEndoplasmic reticulum to nucleus signaling 2. (877 aa)
Fzd5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (584 aa)
pdgfcPlatelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (341 aa)
ENSAMXP00000030711G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (179 aa)
il34Interleukin 34. (210 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (809 aa)
LOC103036474Programmed cell death 10a. (210 aa)
LOC103027348Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (146 aa)
LOC103044392Uncharacterized protein. (300 aa)
LOC103032641Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (526 aa)
LOC107197829PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (166 aa)
ENSAMXP00000036986Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
ENSAMXP00000038137Dopamine receptor D4b; Belongs to the G-protein coupled receptor 1 family. (376 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
epgnEpithelial mitogen homolog (mouse). (155 aa)
map2k5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (467 aa)
LOC111190374Uncharacterized protein. (256 aa)
drd4Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (387 aa)
ENSAMXP00000041061Mitogen-activated protein kinase kinase 7. (511 aa)
pik3r5Phosphoinositide-3-kinase, regulatory subunit 5. (880 aa)
ENSAMXP00000042552Uncharacterized protein. (809 aa)
LOC103038135Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (169 aa)
LOC111194997Interleukin-1. (276 aa)
LOC103044858Transforming growth factor, alpha. (186 aa)
LOC103025686G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (439 aa)
ENSAMXP00000045985Uncharacterized protein. (904 aa)
ENSAMXP00000046425Interleukin-1. (252 aa)
ENSAMXP00000047619CD40 molecule, TNF receptor superfamily member 5. (353 aa)
ENSAMXP00000047894Endothelin 1. (162 aa)
LOC103029481Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (208 aa)
LOC103046764Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
ENSAMXP00000049295Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (231 aa)
ENSAMXP00000049817TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (165 aa)
sash1SAM and SH3 domain containing 1a. (1358 aa)
ENSAMXP00000050565Dickkopf WNT signaling pathway inhibitor 1a. (277 aa)
LOC103038583Tumor necrosis factor receptor superfamily, member 11a, NFKB activator. (582 aa)
ENSAMXP00000052402TNF superfamily member 11; Belongs to the tumor necrosis factor family. (231 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
ENSAMXP00000053072Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (236 aa)
map3k13Mitogen-activated protein kinase kinase kinase. (1007 aa)
ENSAMXP00000055082Dual specificity phosphatase 19a. (209 aa)
W5K095_ASTMXEndoplasmic reticulum to nucleus signaling 1. (1041 aa)
Htr2b5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (467 aa)
LOC103032217Dickkopf_N domain-containing protein. (277 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (526 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.