27 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ilk	Integrin-linked kinase. (452 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	mertk	C-mer proto-oncogene tyrosine kinase a. (943 aa)
	rps6kb2	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (464 aa)
	LOC103041009	Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
	mkrn2	Makorin, ring finger protein, 2. (413 aa)
	W5KNU4_ASTMX	Sphingomyelin phosphodiesterase 3, neutral. (613 aa)
	LOC103024607	Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
	W5KTH2_ASTMX	TSC complex subunit 2. (1705 aa)
	SETX	Senataxin. (2327 aa)
	LOC103036059	Platelet endothelial aggregation receptor 1. (1030 aa)
	rps6kb1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (502 aa)
	LOC103044392	Uncharacterized protein. (300 aa)
	nkx3-1	NK3 homeobox 1. (202 aa)
	TMEM100	Uncharacterized protein. (139 aa)
	LOC103035447	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (265 aa)
	LOC111190374	Uncharacterized protein. (256 aa)
	gas6	Uncharacterized protein. (659 aa)
	Flcn	Folliculin. (564 aa)
	LOC111194997	Interleukin-1. (276 aa)
	ENSAMXP00000046425	Interleukin-1. (252 aa)
	ENSAMXP00000047619	CD40 molecule, TNF receptor superfamily member 5. (353 aa)
	axl	Uncharacterized protein. (911 aa)
	ENSAMXP00000049817	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (165 aa)
	ENSAMXP00000052402	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (231 aa)
	TMEM100-2	Transmembrane protein 100. (147 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000046425	ENSAMXP00000047619	ENSAMXP00000046425	ENSAMXP00000047619	Interleukin-1.	CD40 molecule, TNF receptor superfamily member 5.	0.424
ENSAMXP00000046425	LOC103024607	ENSAMXP00000046425	ENSAMXP00000010023	Interleukin-1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.403
ENSAMXP00000046425	LOC103041009	ENSAMXP00000046425	ENSAMXP00000005247	Interleukin-1.	Tumor necrosis factor b (TNF superfamily, member 2).	0.763
ENSAMXP00000046425	LOC103044392	ENSAMXP00000046425	ENSAMXP00000033888	Interleukin-1.	Uncharacterized protein.	0.404
ENSAMXP00000046425	LOC111190374	ENSAMXP00000046425	ENSAMXP00000040622	Interleukin-1.	Uncharacterized protein.	0.404
ENSAMXP00000046425	LOC111194997	ENSAMXP00000046425	ENSAMXP00000044776	Interleukin-1.	Interleukin-1.	0.900
ENSAMXP00000046425	tgfb1	ENSAMXP00000046425	ENSAMXP00000002667	Interleukin-1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.403
ENSAMXP00000047619	ENSAMXP00000046425	ENSAMXP00000047619	ENSAMXP00000046425	CD40 molecule, TNF receptor superfamily member 5.	Interleukin-1.	0.424
ENSAMXP00000047619	ENSAMXP00000049817	ENSAMXP00000047619	ENSAMXP00000049817	CD40 molecule, TNF receptor superfamily member 5.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.730
ENSAMXP00000047619	ENSAMXP00000052402	ENSAMXP00000047619	ENSAMXP00000052402	CD40 molecule, TNF receptor superfamily member 5.	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	0.730
ENSAMXP00000047619	LOC103041009	ENSAMXP00000047619	ENSAMXP00000005247	CD40 molecule, TNF receptor superfamily member 5.	Tumor necrosis factor b (TNF superfamily, member 2).	0.696
ENSAMXP00000047619	LOC111194997	ENSAMXP00000047619	ENSAMXP00000044776	CD40 molecule, TNF receptor superfamily member 5.	Interleukin-1.	0.424
ENSAMXP00000049817	ENSAMXP00000047619	ENSAMXP00000049817	ENSAMXP00000047619	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	CD40 molecule, TNF receptor superfamily member 5.	0.730
ENSAMXP00000049817	LOC103041009	ENSAMXP00000049817	ENSAMXP00000005247	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Tumor necrosis factor b (TNF superfamily, member 2).	0.561
ENSAMXP00000049817	LOC103044392	ENSAMXP00000049817	ENSAMXP00000033888	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.684
ENSAMXP00000049817	LOC111190374	ENSAMXP00000049817	ENSAMXP00000040622	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.684
ENSAMXP00000052402	ENSAMXP00000047619	ENSAMXP00000052402	ENSAMXP00000047619	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	CD40 molecule, TNF receptor superfamily member 5.	0.730
ENSAMXP00000052402	LOC103041009	ENSAMXP00000052402	ENSAMXP00000005247	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	Tumor necrosis factor b (TNF superfamily, member 2).	0.576
ENSAMXP00000052402	LOC103044392	ENSAMXP00000052402	ENSAMXP00000033888	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.684
ENSAMXP00000052402	LOC111190374	ENSAMXP00000052402	ENSAMXP00000040622	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.684