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med1 med1 W5K0L4_ASTMX W5K0L4_ASTMX bves bves LOC103032217 LOC103032217 W5KDJ8_ASTMX W5KDJ8_ASTMX W5KFM9_ASTMX W5KFM9_ASTMX W5KGH6_ASTMX W5KGH6_ASTMX W5KGK8_ASTMX W5KGK8_ASTMX zdhhc21 zdhhc21 W5KJZ4_ASTMX W5KJZ4_ASTMX asah1 asah1 ercc2 ercc2 LOC103022779 LOC103022779 W5KT32_ASTMX W5KT32_ASTMX lats1 lats1 W5KUR6_ASTMX W5KUR6_ASTMX W5KYV3_ASTMX W5KYV3_ASTMX W5L151_ASTMX W5L151_ASTMX Dhcr24 Dhcr24 traf3ip2 traf3ip2 itgb4 itgb4 abcb6 abcb6 W5L7B9_ASTMX W5L7B9_ASTMX LOC103032002 LOC103032002 W5L834_ASTMX W5L834_ASTMX LOC103036607 LOC103036607 W5LC12_ASTMX W5LC12_ASTMX W5LD66_ASTMX W5LD66_ASTMX Trpc4ap Trpc4ap foxn1 foxn1 fbln1 fbln1 dkk1 dkk1 LOC103022359 LOC103022359 LOC103045821 LOC103045821 LOC103025286 LOC103025286 LOC103029394 LOC103029394 ugcg ugcg fras1 fras1 LOC103027006 LOC103027006 W5LTE8_ASTMX W5LTE8_ASTMX W5LUK9_ASTMX W5LUK9_ASTMX ENSAMXP00000028268 ENSAMXP00000028268 LOC103040875 LOC103040875 ENSAMXP00000028486 ENSAMXP00000028486 SRF SRF ENSAMXP00000029463 ENSAMXP00000029463 ENSAMXP00000029725 ENSAMXP00000029725 stard7 stard7 Eda Eda LOC103042872 LOC103042872 kdf1 kdf1 ENSAMXP00000033124 ENSAMXP00000033124 zmpste24 zmpste24 ENSAMXP00000034482 ENSAMXP00000034482 errfi1 errfi1 smo smo LOC103026839 LOC103026839 llgl2 llgl2 opn3 opn3 sav1 sav1 ENSAMXP00000037899 ENSAMXP00000037899 LOC103041046 LOC103041046 ENSAMXP00000039238 ENSAMXP00000039238 fgf7 fgf7 wnt16 wnt16 LOC103047025 LOC103047025 ENSAMXP00000042051 ENSAMXP00000042051 LOC103038145 LOC103038145 sostdc1 sostdc1 ENSAMXP00000043951 ENSAMXP00000043951 fa2h fa2h ENSAMXP00000044610 ENSAMXP00000044610 LOC103026677 LOC103026677 LOC103047777 LOC103047777 ENSAMXP00000045776 ENSAMXP00000045776 LOC103040240 LOC103040240 tsg101 tsg101 ENSAMXP00000048109 ENSAMXP00000048109 ENSAMXP00000048166 ENSAMXP00000048166 tbc1d31 tbc1d31 ENSAMXP00000049111 ENSAMXP00000049111 LOC103041493 LOC103041493 LOC103041807 LOC103041807 nom1 nom1 ENSAMXP00000050565 ENSAMXP00000050565 lats2 lats2 LOC103042476 LOC103042476 LOC103040974 LOC103040974 LOC103036326 LOC103036326 ENSAMXP00000053345 ENSAMXP00000053345 LOC103042429 LOC103042429 Fosl2 Fosl2 ift74 ift74 LOC103040573 LOC103040573 ENSAMXP00000053435 ENSAMXP00000053435
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1801 aa)
W5K0L4_ASTMXMADS-box domain-containing protein. (479 aa)
bvesBlood vessel epicardial substance. (359 aa)
LOC103032217Dickkopf_N domain-containing protein. (277 aa)
W5KDJ8_ASTMXJunction plakoglobin b. (709 aa)
W5KFM9_ASTMXSHANK-associated RH domain interacting protein. (377 aa)
W5KGH6_ASTMXNeurofibromin 1b. (2733 aa)
W5KGK8_ASTMXSolute carrier family 27 member 4. (582 aa)
zdhhc21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (264 aa)
W5KJZ4_ASTMXTumor susceptibility 101b. (358 aa)
asah1N-acylsphingosine amidohydrolase (acid ceramidase) 1b; Belongs to the acid ceramidase family. (392 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
LOC103022779Ash1 (absent, small, or homeotic)-like (Drosophila). (2955 aa)
W5KT32_ASTMXNeurofibromin 1a. (2744 aa)
lats1Large tumor suppressor kinase 1. (1109 aa)
W5KUR6_ASTMXPolycystic kidney disease 1a. (4355 aa)
W5KYV3_ASTMXSEFIR domain-containing protein. (102 aa)
W5L151_ASTMXFork-head domain-containing protein. (268 aa)
Dhcr2424-dehydrocholesterol reductase. (503 aa)
traf3ip2SEFIR domain-containing protein. (427 aa)
itgb4Integrin beta. (1986 aa)
abcb6ATP-binding cassette, sub-family B (MDR/TAP), member 6a. (848 aa)
W5L7B9_ASTMXFibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (665 aa)
LOC103032002Integrin, alpha 3a; Belongs to the integrin alpha chain family. (995 aa)
W5L834_ASTMXFibroblast growth factor receptor. (735 aa)
LOC103036607Bromo domain-containing protein. (1917 aa)
W5LC12_ASTMXATP-binding cassette, sub-family B (MDR/TAP), member 6b. (576 aa)
W5LD66_ASTMXMothers against decapentaplegic homolog. (573 aa)
Trpc4apTransient receptor potential cation channel, subfamily C, member 4 associated protein b. (785 aa)
foxn1Forkhead box N1. (582 aa)
fbln1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (681 aa)
dkk1Dickkopf WNT signaling pathway inhibitor 1b. (243 aa)
LOC103022359Mothers against decapentaplegic homolog. (587 aa)
LOC103045821Junction plakoglobin a. (724 aa)
LOC103025286Transmembrane protein 79b. (426 aa)
LOC103029394Mothers against decapentaplegic homolog. (544 aa)
ugcgUDP-glucose ceramide glucosyltransferase. (393 aa)
fras1Fraser extracellular matrix complex subunit 1. (3998 aa)
LOC103027006Gap junction protein beta 3. (253 aa)
W5LTE8_ASTMXIF rod domain-containing protein; Belongs to the intermediate filament family. (527 aa)
W5LUK9_ASTMXConnexin 35.4. (251 aa)
ENSAMXP00000028268Kazrin, periplakin interacting protein b. (499 aa)
LOC103040875Keratin 4; Belongs to the intermediate filament family. (498 aa)
ENSAMXP00000028486Mothers against decapentaplegic homolog. (493 aa)
SRFSerum response factor. (527 aa)
ENSAMXP00000029463TRAF3 interacting protein 2-like. (421 aa)
ENSAMXP00000029725Fork-head domain-containing protein. (290 aa)
stard7StAR-related lipid transfer (START) domain containing 7. (403 aa)
EdaEctodysplasin A; Belongs to the tumor necrosis factor family. (449 aa)
LOC103042872Insulin-like growth factor binding protein 5a. (270 aa)
kdf1Keratinocyte differentiation factor 1a. (434 aa)
ENSAMXP00000033124Uncharacterized protein. (309 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (470 aa)
ENSAMXP00000034482Kazrin, periplakin interacting protein a. (630 aa)
errfi1ERBB receptor feedback inhibitor 1a. (480 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (840 aa)
LOC103026839Thioredoxin interacting protein a. (399 aa)
llgl2LLGL scribble cell polarity complex component 2. (1041 aa)
opn3Opsin 3. (398 aa)
sav1Salvador family WW domain containing protein 1. (405 aa)
ENSAMXP00000037899MADS-box domain-containing protein. (356 aa)
LOC103041046Sclerostin domain containing 1b. (187 aa)
ENSAMXP00000039238annotation not available (205 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (199 aa)
wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
LOC103047025Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (312 aa)
ENSAMXP00000042051Integrin beta; Belongs to the integrin beta chain family. (503 aa)
LOC103038145TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (362 aa)
sostdc1Sclerostin domain containing 1a. (227 aa)
ENSAMXP00000043951Integrin beta. (210 aa)
fa2hFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
ENSAMXP00000044610Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (313 aa)
LOC103026677Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (326 aa)
LOC103047777Transmembrane protein 79a. (337 aa)
ENSAMXP00000045776Nerve growth factor receptor a (TNFR superfamily, member 16). (419 aa)
LOC103040240Stathmin 1b. (220 aa)
tsg101Tumor susceptibility 101a. (390 aa)
ENSAMXP00000048109Zgc:123278. (190 aa)
ENSAMXP00000048166Cornifelin. (133 aa)
tbc1d31TBC1 domain family, member 31. (1083 aa)
ENSAMXP00000049111N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family. (412 aa)
LOC103041493Zgc:158846; Belongs to the intermediate filament family. (474 aa)
LOC103041807Keratin 5; Belongs to the intermediate filament family. (574 aa)
nom1Nucleolar protein with MIF4G domain 1. (864 aa)
ENSAMXP00000050565Dickkopf WNT signaling pathway inhibitor 1a. (277 aa)
lats2Large tumor suppressor kinase 2. (1139 aa)
LOC103042476Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
LOC103040974Phospholipase A(2). (153 aa)
LOC103036326Thioredoxin interacting protein b. (395 aa)
ENSAMXP00000053345MH1 domain-containing protein. (187 aa)
LOC103042429Keratin 8; Belongs to the intermediate filament family. (526 aa)
Fosl2Fos-like antigen 2. (332 aa)
ift74Intraflagellar transport 74. (599 aa)
LOC103040573Integrin, alpha 3b; Belongs to the integrin alpha chain family. (1040 aa)
ENSAMXP00000053435Uncharacterized protein. (143 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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