21 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W5KSM1_ASTMX	ATPase family AAA domain containing 5a. (1807 aa)
	LOC103024607	Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
	hmces	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (358 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	Tbx21	T-box transcription factor 21. (577 aa)
	rif1	Replication timing regulatory factor 1. (2429 aa)
	Nsd2	Nuclear receptor binding SET domain protein 2. (1468 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (939 aa)
	LOC103025343	SET domain-containing protein. (876 aa)
	W5LFE7_ASTMX	Tumor protein p53 binding protein, 1. (1622 aa)
	W5LTF5_ASTMX	Zgc:101664. (247 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (809 aa)
	ENSAMXP00000035313	SET domain-containing protein. (2185 aa)
	ENSAMXP00000037285	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (689 aa)
	ENSAMXP00000042552	Uncharacterized protein. (809 aa)
	ENSAMXP00000043107	TNF superfamily member 13; Belongs to the tumor necrosis factor family. (170 aa)
	exosc3	Exosome component 3. (245 aa)
	kmt5b	Lysine methyltransferase 5B. (829 aa)
	ENSAMXP00000047619	CD40 molecule, TNF receptor superfamily member 5. (353 aa)
	clcf1	Cardiotrophin-like cytokine factor 1. (375 aa)
	ENSAMXP00000052711	ATPase family AAA domain containing 5b. (772 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000035313	W5LFE7_ASTMX	ENSAMXP00000035313	ENSAMXP00000018559	SET domain-containing protein.	Tumor protein p53 binding protein, 1.	0.422
ENSAMXP00000037285	msh2	ENSAMXP00000037285	ENSAMXP00000016339	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.995
ENSAMXP00000052711	msh2	ENSAMXP00000052711	ENSAMXP00000016339	ATPase family AAA domain containing 5b.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.433
LOC103024607	tgfb1	ENSAMXP00000010023	ENSAMXP00000002667	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.902
LOC103025343	W5LFE7_ASTMX	ENSAMXP00000017767	ENSAMXP00000018559	SET domain-containing protein.	Tumor protein p53 binding protein, 1.	0.422
Nsd2	W5LFE7_ASTMX	ENSAMXP00000012840	ENSAMXP00000018559	Nuclear receptor binding SET domain protein 2.	Tumor protein p53 binding protein, 1.	0.726
Nsd2	rif1	ENSAMXP00000012840	ENSAMXP00000011199	Nuclear receptor binding SET domain protein 2.	Replication timing regulatory factor 1.	0.589
W5KSM1_ASTMX	msh2	ENSAMXP00000010583	ENSAMXP00000016339	ATPase family AAA domain containing 5a.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.433
W5LFE7_ASTMX	ENSAMXP00000035313	ENSAMXP00000018559	ENSAMXP00000035313	Tumor protein p53 binding protein, 1.	SET domain-containing protein.	0.422
W5LFE7_ASTMX	LOC103025343	ENSAMXP00000018559	ENSAMXP00000017767	Tumor protein p53 binding protein, 1.	SET domain-containing protein.	0.422
W5LFE7_ASTMX	Nsd2	ENSAMXP00000018559	ENSAMXP00000012840	Tumor protein p53 binding protein, 1.	Nuclear receptor binding SET domain protein 2.	0.726
W5LFE7_ASTMX	W5LTF5_ASTMX	ENSAMXP00000018559	ENSAMXP00000026367	Tumor protein p53 binding protein, 1.	Zgc:101664.	0.418
W5LFE7_ASTMX	kmt5b	ENSAMXP00000018559	ENSAMXP00000046467	Tumor protein p53 binding protein, 1.	Lysine methyltransferase 5B.	0.422
W5LFE7_ASTMX	rif1	ENSAMXP00000018559	ENSAMXP00000011199	Tumor protein p53 binding protein, 1.	Replication timing regulatory factor 1.	0.828
W5LTF5_ASTMX	W5LFE7_ASTMX	ENSAMXP00000026367	ENSAMXP00000018559	Zgc:101664.	Tumor protein p53 binding protein, 1.	0.418
W5LTF5_ASTMX	rif1	ENSAMXP00000026367	ENSAMXP00000011199	Zgc:101664.	Replication timing regulatory factor 1.	0.418
kmt5b	W5LFE7_ASTMX	ENSAMXP00000046467	ENSAMXP00000018559	Lysine methyltransferase 5B.	Tumor protein p53 binding protein, 1.	0.422
msh2	ENSAMXP00000037285	ENSAMXP00000016339	ENSAMXP00000037285	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.995
msh2	ENSAMXP00000052711	ENSAMXP00000016339	ENSAMXP00000052711	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	ATPase family AAA domain containing 5b.	0.433
msh2	W5KSM1_ASTMX	ENSAMXP00000016339	ENSAMXP00000010583	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	ATPase family AAA domain containing 5a.	0.433