(44 nodes) Positive regulation of exocytosis network (Astyanax mexicanus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W5KJZ4_ASTMX	Tumor susceptibility 101b. (358 aa)
	snx4	Sorting nexin 4. (436 aa)
	Pla2g6	Phospholipase A2, group VI (cytosolic, calcium-independent). (822 aa)
	W5K980_ASTMX	Si:ch211-259g3.4. (2139 aa)
	syt7	Synaptotagmin VIIb. (655 aa)
	W5K2U0_ASTMX	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (424 aa)
	LOC103036711	Vesicle-associated membrane protein 8 (endobrevin). (127 aa)
	cadps2	Ca++-dependent secretion activator 2. (1300 aa)
	syt9	Synaptotagmin IXb. (518 aa)
	cadps	Ca2+-dependent activator protein for secretion a. (1274 aa)
	rab27a	RAB27A, member RAS oncogene family. (222 aa)
	LOC103024468	Ca2+-dependent activator protein for secretion b. (1355 aa)
	sdc4	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (244 aa)
	ENSAMXP00000048553	Synaptotagmin IXa. (499 aa)
	ENSAMXP00000048109	Zgc:123278. (190 aa)
	tsg101	Tumor susceptibility 101a. (390 aa)
	ankrd29	Uncharacterized protein; Belongs to the AAA ATPase family. (439 aa)
	rab27b	RAB27B, member RAS oncogene family. (217 aa)
	LOC111197585	ZP domain-containing protein. (416 aa)
	LOC103023058	ZP domain-containing protein. (397 aa)
	SDC1	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (370 aa)
	Hgs	Hepatocyte growth factor-regulated tyrosine kinase substrate. (688 aa)
	LOC111197584	ZP domain-containing protein. (417 aa)
	lamp1	Lysosomal associated membrane protein 1a. (411 aa)
	ENSAMXP00000041204	ZP domain-containing protein. (423 aa)
	atp13a2	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1170 aa)
	LOC103029914	Secretory carrier-associated membrane protein. (230 aa)
	LOC103033944	ZP domain-containing protein. (451 aa)
	LOC111193015	ZP domain-containing protein. (451 aa)
	ENSAMXP00000036671	ZP domain-containing protein. (429 aa)
	ENSAMXP00000033840	Hyaluronidase. (431 aa)
	ENSAMXP00000033395	GATA binding protein 1a. (372 aa)
	ENSAMXP00000032857	ZP domain-containing protein. (214 aa)
	ENSAMXP00000032733	ZP domain-containing protein. (489 aa)
	ENSAMXP00000031958	Synaptotagmin VIIa. (791 aa)
	fgb	Fibrinogen beta chain. (486 aa)
	vps4a	Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (460 aa)
	LOC103042853	Secretory carrier-associated membrane protein. (228 aa)
	ENSAMXP00000029834	Si:dkey-185p13.1. (96 aa)
	pdcd6ip	Programmed cell death 6 interacting protein. (869 aa)
	LOC103031807	Uncharacterized protein. (427 aa)
	stam	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1. (518 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	gab2	GRB2-associated binding protein 2. (666 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000029834	Hgs	ENSAMXP00000029834	ENSAMXP00000043019	Si:dkey-185p13.1.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.521
ENSAMXP00000029834	ankrd29	ENSAMXP00000029834	ENSAMXP00000047134	Si:dkey-185p13.1.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.900
ENSAMXP00000029834	pdcd6ip	ENSAMXP00000029834	ENSAMXP00000021196	Si:dkey-185p13.1.	Programmed cell death 6 interacting protein.	0.748
ENSAMXP00000029834	vps4a	ENSAMXP00000029834	ENSAMXP00000030481	Si:dkey-185p13.1.	Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family.	0.937
ENSAMXP00000048109	Hgs	ENSAMXP00000048109	ENSAMXP00000043019	Zgc:123278.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.956
ENSAMXP00000048109	pdcd6ip	ENSAMXP00000048109	ENSAMXP00000021196	Zgc:123278.	Programmed cell death 6 interacting protein.	0.821
ENSAMXP00000048109	stam	ENSAMXP00000048109	ENSAMXP00000013654	Zgc:123278.	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1.	0.785
ENSAMXP00000048553	LOC103036711	ENSAMXP00000048553	ENSAMXP00000001679	Synaptotagmin IXa.	Vesicle-associated membrane protein 8 (endobrevin).	0.544
Hgs	ENSAMXP00000029834	ENSAMXP00000043019	ENSAMXP00000029834	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Si:dkey-185p13.1.	0.521
Hgs	ENSAMXP00000048109	ENSAMXP00000043019	ENSAMXP00000048109	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Zgc:123278.	0.956
Hgs	LOC103036711	ENSAMXP00000043019	ENSAMXP00000001679	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Vesicle-associated membrane protein 8 (endobrevin).	0.619
Hgs	W5K2U0_ASTMX	ENSAMXP00000043019	ENSAMXP00000001901	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.	0.521
Hgs	W5KJZ4_ASTMX	ENSAMXP00000043019	ENSAMXP00000007906	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Tumor susceptibility 101b.	0.956
Hgs	ankrd29	ENSAMXP00000043019	ENSAMXP00000047134	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.521
Hgs	lamp1	ENSAMXP00000043019	ENSAMXP00000041253	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Lysosomal associated membrane protein 1a.	0.420
Hgs	pdcd6ip	ENSAMXP00000043019	ENSAMXP00000021196	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Programmed cell death 6 interacting protein.	0.749
Hgs	stam	ENSAMXP00000043019	ENSAMXP00000013654	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1.	0.998
Hgs	tsg101	ENSAMXP00000043019	ENSAMXP00000048067	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Tumor susceptibility 101a.	0.956
Hgs	vps4a	ENSAMXP00000043019	ENSAMXP00000030481	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family.	0.521
LOC103036711	ENSAMXP00000048553	ENSAMXP00000001679	ENSAMXP00000048553	Vesicle-associated membrane protein 8 (endobrevin).	Synaptotagmin IXa.	0.544