STRINGSTRING
LOC103034175 LOC103034175 LOC103038513 LOC103038513 W5K2H5_ASTMX W5K2H5_ASTMX Usp9x Usp9x LOC103029280 LOC103029280 smad6 smad6 axin1 axin1 LOC103027845 LOC103027845 drosha drosha W5KF46_ASTMX W5KF46_ASTMX W5KFG3_ASTMX W5KFG3_ASTMX W5KFJ0_ASTMX W5KFJ0_ASTMX men1 men1 snw1 snw1 tgfbrap1 tgfbrap1 LOC103042974 LOC103042974 ACVR1 ACVR1 LOC103028346 LOC103028346 smad5 smad5 LOC103030717 LOC103030717 LOC103030188 LOC103030188 LOC103030012 LOC103030012 W5L1R3_ASTMX W5L1R3_ASTMX LOC103046211 LOC103046211 LOC103027116 LOC103027116 W5LD66_ASTMX W5LD66_ASTMX W5LFP1_ASTMX W5LFP1_ASTMX LOC103022359 LOC103022359 LOC103029394 LOC103029394 W5LJD2_ASTMX W5LJD2_ASTMX tgfbr2 tgfbr2 LOC103021920 LOC103021920 cited1 cited1 LOC103026375 LOC103026375 LOC103043286 LOC103043286 ENSAMXP00000028486 ENSAMXP00000028486 LOC111193684 LOC111193684 LOC103031474 LOC103031474 bmpr1b bmpr1b LOC103027004 LOC103027004 ENSAMXP00000033639 ENSAMXP00000033639 Zc3h3 Zc3h3 axin2 axin2 LOC103024390 LOC103024390 smad2 smad2 ldlrad4 ldlrad4 sav1 sav1 rgcc rgcc smad1 smad1 ENSAMXP00000040747 ENSAMXP00000040747 LOC103042559 LOC103042559 ENSAMXP00000044604 ENSAMXP00000044604 skor2 skor2 LOC103025122 LOC103025122 ranbp3l ranbp3l LOC103041954 LOC103041954 LOC103027811 LOC103027811 LOC103032663 LOC103032663 ranbp3 ranbp3 skil skil LOC103025967 LOC103025967 ENSAMXP00000050762 ENSAMXP00000050762 smad7 smad7 ACVR1C ACVR1C ENSAMXP00000053345 ENSAMXP00000053345 ENSAMXP00000053702 ENSAMXP00000053702
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103034175Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (496 aa)
LOC103038513RAN binding protein 3b. (519 aa)
W5K2H5_ASTMXMembrane associated guanylate kinase, WW and PDZ domain containing 2b. (1253 aa)
Usp9xUbiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2524 aa)
LOC103029280SKI family transcriptional corepressor 1. (771 aa)
smad6Mothers against decapentaplegic homolog. (480 aa)
axin1Axin 1. (866 aa)
LOC103027845SKI-like proto-oncogene b. (715 aa)
droshaDrosha ribonuclease III. (1309 aa)
W5KF46_ASTMXTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (561 aa)
W5KFG3_ASTMXSKI family transcriptional corepressor 1. (611 aa)
W5KFJ0_ASTMXMothers against decapentaplegic homolog. (468 aa)
men1Multiple endocrine neoplasia I. (623 aa)
snw1SNW domain containing 1. (539 aa)
tgfbrap1Transforming growth factor, beta receptor associated protein 1. (927 aa)
LOC103042974Axin 2 (conductin, axil). (838 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (679 aa)
LOC103028346Integrator complex subunit 8. (996 aa)
smad5Mothers against decapentaplegic homolog. (464 aa)
LOC103030717Uncharacterized protein. (750 aa)
LOC103030188DAB adaptor protein 2. (800 aa)
LOC103030012Prostate transmembrane protein, androgen induced 1. (270 aa)
W5L1R3_ASTMXUSP domain-containing protein; Belongs to the peptidase C19 family. (2529 aa)
LOC103046211V-ski avian sarcoma viral oncogene homolog a. (790 aa)
LOC103027116Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
W5LD66_ASTMXMothers against decapentaplegic homolog. (573 aa)
W5LFP1_ASTMXMembrane associated guanylate kinase, WW and PDZ domain containing 2a. (1064 aa)
LOC103022359Mothers against decapentaplegic homolog. (587 aa)
LOC103029394Mothers against decapentaplegic homolog. (544 aa)
W5LJD2_ASTMXReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
LOC103021920JunE proto-oncogene, AP-1 transcription factor subunit. (353 aa)
cited1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (155 aa)
LOC103026375Ankyrin repeat domain 1a (cardiac muscle). (310 aa)
LOC103043286Forkhead box H1. (533 aa)
ENSAMXP00000028486Mothers against decapentaplegic homolog. (493 aa)
LOC111193684Si:ch211-161c3.6. (114 aa)
LOC103031474V-ski avian sarcoma viral oncogene homolog b. (964 aa)
bmpr1bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
LOC103027004Mothers against decapentaplegic homolog. (424 aa)
ENSAMXP00000033639Mothers against decapentaplegic homolog. (425 aa)
Zc3h3Zinc finger CCCH-type containing 3. (1004 aa)
axin2Uncharacterized protein. (820 aa)
LOC103024390Si:ch211-204c21.1. (696 aa)
smad2Mothers against decapentaplegic homolog. (468 aa)
ldlrad4Low density lipoprotein receptor class A domain containing 4a. (311 aa)
sav1Salvador family WW domain containing protein 1. (405 aa)
rgccRegulator of cell cycle. (128 aa)
smad1Mothers against decapentaplegic homolog. (488 aa)
ENSAMXP00000040747Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (578 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
ENSAMXP00000044604Uncharacterized protein. (266 aa)
skor2SKI family transcriptional corepressor 2. (758 aa)
LOC103025122Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (531 aa)
ranbp3lRAN binding protein 3 like. (459 aa)
LOC103041954Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (494 aa)
LOC103027811Mothers against decapentaplegic homolog. (425 aa)
LOC103032663Low density lipoprotein receptor class A domain containing 4b. (331 aa)
ranbp3RanBD1 domain-containing protein. (515 aa)
skilSKI-like proto-oncogene a. (681 aa)
LOC103025967Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
ENSAMXP00000050762Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (531 aa)
smad7Mothers against decapentaplegic homolog. (390 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (495 aa)
ENSAMXP00000053345MH1 domain-containing protein. (187 aa)
ENSAMXP00000053702Uncharacterized protein. (283 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.