17 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103032591	E3 ubiquitin-protein ligase. (853 aa)
	LOC103041682	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (331 aa)
	card11	Caspase recruitment domain family, member 11. (1126 aa)
	LOC103027415	Interferon regulatory factor. (310 aa)
	sh3rf1	SH3 domain containing ring finger 1. (884 aa)
	tgfbr2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
	LOC103047365	Galectin. (359 aa)
	LOC103022206	E3 ubiquitin-protein ligase. (874 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (809 aa)
	ENSAMXP00000033608	Galectin. (306 aa)
	LOC111194477	DNA helicase; Belongs to the MCM family. (827 aa)
	LOC103044019	Tyrosine-protein kinase. (612 aa)
	Syk	Tyrosine-protein kinase. (631 aa)
	ENSAMXP00000042552	Uncharacterized protein. (809 aa)
	LOC103042559	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
	vsir	V-set immunoregulatory receptor. (283 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (579 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000033608	ENSAMXP00000042552	ENSAMXP00000033608	ENSAMXP00000042552	Galectin.	Uncharacterized protein.	0.435
ENSAMXP00000033608	PTPRC	ENSAMXP00000033608	ENSAMXP00000032906	Galectin.	Protein tyrosine phosphatase receptor type C.	0.435
ENSAMXP00000042552	ENSAMXP00000033608	ENSAMXP00000042552	ENSAMXP00000033608	Uncharacterized protein.	Galectin.	0.435
ENSAMXP00000042552	LOC103047365	ENSAMXP00000042552	ENSAMXP00000029967	Uncharacterized protein.	Galectin.	0.435
LOC103022206	LOC103032591	ENSAMXP00000030199	ENSAMXP00000000937	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.900
LOC103022206	RIPK2	ENSAMXP00000030199	ENSAMXP00000053355	E3 ubiquitin-protein ligase.	Receptor interacting serine/threonine kinase 2.	0.579
LOC103032591	LOC103022206	ENSAMXP00000000937	ENSAMXP00000030199	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.900
LOC103032591	RIPK2	ENSAMXP00000000937	ENSAMXP00000053355	E3 ubiquitin-protein ligase.	Receptor interacting serine/threonine kinase 2.	0.579
LOC103042559	tgfbr2	ENSAMXP00000043824	ENSAMXP00000021003	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.902
LOC103044019	card11	ENSAMXP00000037388	ENSAMXP00000010096	Tyrosine-protein kinase.	Caspase recruitment domain family, member 11.	0.563
LOC103047365	ENSAMXP00000042552	ENSAMXP00000029967	ENSAMXP00000042552	Galectin.	Uncharacterized protein.	0.435
LOC103047365	PTPRC	ENSAMXP00000029967	ENSAMXP00000032906	Galectin.	Protein tyrosine phosphatase receptor type C.	0.435
PTPRC	ENSAMXP00000033608	ENSAMXP00000032906	ENSAMXP00000033608	Protein tyrosine phosphatase receptor type C.	Galectin.	0.435
PTPRC	LOC103047365	ENSAMXP00000032906	ENSAMXP00000029967	Protein tyrosine phosphatase receptor type C.	Galectin.	0.435
RIPK2	LOC103022206	ENSAMXP00000053355	ENSAMXP00000030199	Receptor interacting serine/threonine kinase 2.	E3 ubiquitin-protein ligase.	0.579
RIPK2	LOC103032591	ENSAMXP00000053355	ENSAMXP00000000937	Receptor interacting serine/threonine kinase 2.	E3 ubiquitin-protein ligase.	0.579
RIPK2	card11	ENSAMXP00000053355	ENSAMXP00000010096	Receptor interacting serine/threonine kinase 2.	Caspase recruitment domain family, member 11.	0.593
Syk	card11	ENSAMXP00000040943	ENSAMXP00000010096	Tyrosine-protein kinase.	Caspase recruitment domain family, member 11.	0.563
card11	LOC103044019	ENSAMXP00000010096	ENSAMXP00000037388	Caspase recruitment domain family, member 11.	Tyrosine-protein kinase.	0.563
card11	RIPK2	ENSAMXP00000010096	ENSAMXP00000053355	Caspase recruitment domain family, member 11.	Receptor interacting serine/threonine kinase 2.	0.593