36 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103042959	Activated leukocyte cell adhesion molecule b. (564 aa)
	W5K3H8_ASTMX	Neuroblastoma amplified sequence. (2244 aa)
	LOC103021856	Bone morphogenetic protein 2a. (405 aa)
	phf8	PHD finger protein 8. (1046 aa)
	LOC103039334	RAD21 cohesin complex component a. (637 aa)
	Wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
	egr1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (523 aa)
	LOC103028976	Bone morphogenetic protein 2b. (445 aa)
	LOC103043816	RNA polymerase I and III subunit D. (138 aa)
	LOC103032897	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
	hand2	Heart and neural crest derivatives expressed 2. (200 aa)
	LOC103035751	Follistatin b. (362 aa)
	ENSAMXP00000030426	Caspase a; Belongs to the peptidase C14A family. (352 aa)
	ENSAMXP00000029247	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
	alcam	Activated leukocyte cell adhesion molecule a. (565 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (429 aa)
	dlx1	Distal-less homeobox 1a. (254 aa)
	rad21	RAD21 cohesin complex component b. (636 aa)
	W5LMI9_ASTMX	T-box transcription factor 1. (417 aa)
	LOC103043058	Lysyl oxidase-like 3b. (796 aa)
	pitx2	Homeobox protein. (300 aa)
	fst	Follistatin a. (347 aa)
	dlx3	Distal-less homeobox 3b. (265 aa)
	dlx5	Distal-less homeobox 5a. (276 aa)
	LOC103029147	Distal-less homeobox 4b. (231 aa)
	wnt5a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
	ENSAMXP00000043285	Caspase a; Belongs to the peptidase C14A family. (386 aa)
	ENSAMXP00000041750	Uncharacterized protein. (104 aa)
	mmachc	Metabolism of cobalamin associated C. (256 aa)
	gnptab	N-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1220 aa)
	TBX10	T-box transcription factor 10. (196 aa)
	dlx2	Dlx2a. (277 aa)
	Med12	Mediator complex subunit 12. (2026 aa)
	nipbl	Nipped-B protein. (2745 aa)
	LOC103030832	RAD21 cohesin complex component like 1. (550 aa)
	S1pr2	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (356 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000029247	Wnt4	ENSAMXP00000029247	ENSAMXP00000035119	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.638
ENSAMXP00000029247	shh	ENSAMXP00000029247	ENSAMXP00000028286	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.548
ENSAMXP00000029247	wnt5a	ENSAMXP00000029247	ENSAMXP00000044616	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.912
ENSAMXP00000041750	LOC103030832	ENSAMXP00000041750	ENSAMXP00000013363	Uncharacterized protein.	RAD21 cohesin complex component like 1.	0.905
ENSAMXP00000041750	LOC103039334	ENSAMXP00000041750	ENSAMXP00000032739	Uncharacterized protein.	RAD21 cohesin complex component a.	0.905
ENSAMXP00000041750	rad21	ENSAMXP00000041750	ENSAMXP00000021316	Uncharacterized protein.	RAD21 cohesin complex component b.	0.905
LOC103021856	LOC103035751	ENSAMXP00000000963	ENSAMXP00000031549	Bone morphogenetic protein 2a.	Follistatin b.	0.430
LOC103021856	dlx5	ENSAMXP00000000963	ENSAMXP00000044944	Bone morphogenetic protein 2a.	Distal-less homeobox 5a.	0.476
LOC103021856	fst	ENSAMXP00000000963	ENSAMXP00000050722	Bone morphogenetic protein 2a.	Follistatin a.	0.430
LOC103028976	LOC103035751	ENSAMXP00000035663	ENSAMXP00000031549	Bone morphogenetic protein 2b.	Follistatin b.	0.430
LOC103028976	dlx5	ENSAMXP00000035663	ENSAMXP00000044944	Bone morphogenetic protein 2b.	Distal-less homeobox 5a.	0.476
LOC103028976	fst	ENSAMXP00000035663	ENSAMXP00000050722	Bone morphogenetic protein 2b.	Follistatin a.	0.431
LOC103030832	ENSAMXP00000041750	ENSAMXP00000013363	ENSAMXP00000041750	RAD21 cohesin complex component like 1.	Uncharacterized protein.	0.905
LOC103030832	LOC103039334	ENSAMXP00000013363	ENSAMXP00000032739	RAD21 cohesin complex component like 1.	RAD21 cohesin complex component a.	0.903
LOC103030832	nipbl	ENSAMXP00000013363	ENSAMXP00000007077	RAD21 cohesin complex component like 1.	Nipped-B protein.	0.905
LOC103030832	rad21	ENSAMXP00000013363	ENSAMXP00000021316	RAD21 cohesin complex component like 1.	RAD21 cohesin complex component b.	0.903
LOC103032897	dlx2	ENSAMXP00000036419	ENSAMXP00000011724	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Dlx2a.	0.407
LOC103032897	pitx2	ENSAMXP00000036419	ENSAMXP00000054910	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Homeobox protein.	0.499
LOC103035751	LOC103021856	ENSAMXP00000031549	ENSAMXP00000000963	Follistatin b.	Bone morphogenetic protein 2a.	0.430
LOC103035751	LOC103028976	ENSAMXP00000031549	ENSAMXP00000035663	Follistatin b.	Bone morphogenetic protein 2b.	0.430