STRINGSTRING
LOC103043816 LOC103043816 lrp6 lrp6 LOC103021856 LOC103021856 sema3d sema3d W5K3H8_ASTMX W5K3H8_ASTMX frem1 frem1 Pdgfra Pdgfra sec23a sec23a LOC103042959 LOC103042959 LOC103026658 LOC103026658 atg9a atg9a fam20b fam20b Lrp5 Lrp5 rnf2 rnf2 Sox6 Sox6 nipbl nipbl hoxd4 hoxd4 ccn2 ccn2 LOC103036054 LOC103036054 gnptab gnptab Sox5 Sox5 W5KN49_ASTMX W5KN49_ASTMX LOC103022868 LOC103022868 W5KQ85_ASTMX W5KQ85_ASTMX TBX10 TBX10 LOC103046861 LOC103046861 W5KUR6_ASTMX W5KUR6_ASTMX dlx2 dlx2 Med12 Med12 fuz fuz LOC103030832 LOC103030832 disp1 disp1 W5L1E4_ASTMX W5L1E4_ASTMX W5L312_ASTMX W5L312_ASTMX LOC103042439 LOC103042439 W5L4C1_ASTMX W5L4C1_ASTMX flt3 flt3 rab23 rab23 LOC103026885 LOC103026885 hoxb4 hoxb4 plxna1 plxna1 W5LCK6_ASTMX W5LCK6_ASTMX W5LE75_ASTMX W5LE75_ASTMX tgfbr2 tgfbr2 W5LMI9_ASTMX W5LMI9_ASTMX rad21 rad21 Trip11 Trip11 LOC103044922 LOC103044922 LOC103045279 LOC103045279 MAB21L1 MAB21L1 LOC103043606 LOC103043606 LOC103042468 LOC103042468 LOC103047714 LOC103047714 kat2a kat2a LOC103029234 LOC103029234 dlx1 dlx1 ankrd11 ankrd11 LOC103042774 LOC103042774 shh shh alcam alcam LOC103034626 LOC103034626 ENSAMXP00000029247 ENSAMXP00000029247 setd2 setd2 LOC103043019 LOC103043019 sgpl1 sgpl1 nle1 nle1 fgf4 fgf4 Bmpr2 Bmpr2 ENSAMXP00000030426 ENSAMXP00000030426 LOC103033177 LOC103033177 LOC103033248 LOC103033248 edar edar CDH2 CDH2 LOC103035751 LOC103035751 Wdr19 Wdr19 mab21l2 mab21l2 hand2 hand2 fgf6 fgf6 fgf8 fgf8 Wdr60 Wdr60 LOC103039334 LOC103039334 LOC103028218 LOC103028218 phf8 phf8 zmpste24 zmpste24 LOC103032320 LOC103032320 dhrs3 dhrs3 MSX1 MSX1 S1pr2 S1pr2 Wnt4 Wnt4 Fgf3 Fgf3 egr1 egr1 rflna rflna LOC103046901 LOC103046901 LOC103028976 LOC103028976 LOC103032897 LOC103032897 hoxb9 hoxb9 tcf15 tcf15 rflnb rflnb ryk ryk ift140 ift140 LOC103021477 LOC103021477 hhip hhip LOC103046321 LOC103046321 LOC103042886 LOC103042886 LOC103033204 LOC103033204 ENSAMXP00000040343 ENSAMXP00000040343 OTOR OTOR mmachc mmachc hoxd3 hoxd3 ENSAMXP00000041750 ENSAMXP00000041750 Rab33b Rab33b ENSAMXP00000042910 ENSAMXP00000042910 ENSAMXP00000043285 ENSAMXP00000043285 anxa6 anxa6 Ilvbl Ilvbl LOC103029459 LOC103029459 LOC103039097 LOC103039097 LOC103042559 LOC103042559 rap1b rap1b wnt5a wnt5a LOC103029147 LOC103029147 dlx5 dlx5 ext2 ext2 LOC103042410 LOC103042410 RING1 RING1 foxn3 foxn3 LOC103030680 LOC103030680 dlx3 dlx3 LOC103026589 LOC103026589 pex7 pex7 hoxc9 hoxc9 LOC103029481 LOC103029481 LOC103038759 LOC103038759 Alx1 Alx1 sp5 sp5 ENSAMXP00000049034 ENSAMXP00000049034 LOC103046764 LOC103046764 LOC103041475 LOC103041475 hoxa3 hoxa3 mef2d mef2d LOC103029799 LOC103029799 gata3 gata3 fst fst ENSAMXP00000051962 ENSAMXP00000051962 rbm24 rbm24 ENSAMXP00000053491 ENSAMXP00000053491 zfand5 zfand5 ALX3 ALX3 rap1a rap1a pitx2 pitx2 LOC103043058 LOC103043058
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103043816RNA polymerase I and III subunit D. (138 aa)
lrp6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1618 aa)
LOC103021856Bone morphogenetic protein 2a. (405 aa)
sema3dSema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (787 aa)
W5K3H8_ASTMXNeuroblastoma amplified sequence. (2244 aa)
frem1Fras1 related extracellular matrix 1a. (2182 aa)
PdgfraPlatelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (995 aa)
sec23aProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
LOC103042959Activated leukocyte cell adhesion molecule b. (564 aa)
LOC103026658Plexin A1a. (1899 aa)
atg9aAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (846 aa)
fam20bFAM20B glycosaminoglycan xylosylkinase. (409 aa)
Lrp5Low density lipoprotein receptor-related protein 5. (1518 aa)
rnf2Ring finger protein 2. (336 aa)
Sox6SRY-box transcription factor 6. (787 aa)
nipblNipped-B protein. (2745 aa)
hoxd4Homeobox D4a. (256 aa)
ccn2Cellular communication network factor 2a. (362 aa)
LOC103036054MyoD family inhibitor. (288 aa)
gnptabN-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1220 aa)
Sox5SRY-box transcription factor 5. (763 aa)
W5KN49_ASTMXUncharacterized protein; Belongs to the heparin-binding growth factors family. (67 aa)
LOC103022868RAP1A, member of RAS oncogene family b. (185 aa)
W5KQ85_ASTMXCheckpoint suppressor 1. (334 aa)
TBX10T-box transcription factor 10. (196 aa)
LOC103046861Peroxisome proliferator-activated receptor gamma, coactivator 1 beta. (844 aa)
W5KUR6_ASTMXPolycystic kidney disease 1a. (4355 aa)
dlx2Dlx2a. (277 aa)
Med12Mediator complex subunit 12. (2026 aa)
fuzFuzzy planar cell polarity protein. (448 aa)
LOC103030832RAD21 cohesin complex component like 1. (550 aa)
disp1Dispatched homolog 1 (Drosophila). (1522 aa)
W5L1E4_ASTMXAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (744 aa)
W5L312_ASTMXIntraflagellar transport 80 homolog (Chlamydomonas). (768 aa)
LOC103042439Zgc:77486. (216 aa)
W5L4C1_ASTMXNGFI-A binding protein 2 (EGR1 binding protein 2). (459 aa)
flt3Fms-related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (983 aa)
rab23RAB23, member RAS oncogene family. (237 aa)
LOC103026885Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (796 aa)
hoxb4Homeobox B4a. (244 aa)
plxna1Sema domain-containing protein. (1889 aa)
W5LCK6_ASTMXPlatelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1068 aa)
W5LE75_ASTMXPlexin A3. (1197 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
W5LMI9_ASTMXT-box transcription factor 1. (417 aa)
rad21RAD21 cohesin complex component b. (636 aa)
Trip11Thyroid hormone receptor interactor 11. (1949 aa)
LOC103044922Dehydrogenase/reductase (SDR family) member 3a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (303 aa)
LOC103045279Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
MAB21L1Mab-21-like 1. (359 aa)
LOC103043606Uncharacterized protein. (347 aa)
LOC103042468Uncharacterized protein. (347 aa)
LOC103047714Transmembrane protein 119b. (295 aa)
kat2aK(lysine) acetyltransferase 2A. (855 aa)
LOC103029234Homeobox domain-containing protein. (346 aa)
dlx1Distal-less homeobox 1a. (254 aa)
ankrd11Ankyrin repeat domain 11. (2857 aa)
LOC103042774Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family. (403 aa)
shhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (429 aa)
alcamActivated leukocyte cell adhesion molecule a. (565 aa)
LOC103034626Si:ch211-246m6.4. (198 aa)
ENSAMXP00000029247Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
setd2SET domain containing 2, histone lysine methyltransferase. (2886 aa)
LOC103043019Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a. (371 aa)
sgpl1Sphingosine-1-phosphate lyase 1. (572 aa)
nle1Notchless homolog 1 (Drosophila). (476 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (191 aa)
Bmpr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
ENSAMXP00000030426Caspase a; Belongs to the peptidase C14A family. (352 aa)
LOC103033177Cytochrome P450, family 26, subfamily b, polypeptide 1; Belongs to the cytochrome P450 family. (511 aa)
LOC103033248Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (263 aa)
edarEctodysplasin A receptor. (468 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (903 aa)
LOC103035751Follistatin b. (362 aa)
Wdr19WD repeat domain 19. (1339 aa)
mab21l2Mab-21-like 2. (359 aa)
hand2Heart and neural crest derivatives expressed 2. (200 aa)
fgf6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
Wdr60WD repeat domain 60. (717 aa)
LOC103039334RAD21 cohesin complex component a. (637 aa)
LOC103028218Golgi glycoprotein 1a. (1152 aa)
phf8PHD finger protein 8. (1046 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (470 aa)
LOC103032320Homeobox C10a. (348 aa)
dhrs3Dehydrogenase/reductase (SDR family) member 3b. (321 aa)
MSX1Msh homeobox 1. (201 aa)
S1pr2Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (356 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
Fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (523 aa)
rflnaRefilin A. (220 aa)
LOC103046901Homeobox B3a. (416 aa)
LOC103028976Bone morphogenetic protein 2b. (445 aa)
LOC103032897Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
hoxb9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (249 aa)
tcf15Transcription factor 15. (178 aa)
rflnbRefilin B. (196 aa)
rykReceptor like tyrosine kinase. (627 aa)
ift140Intraflagellar transport 140 homolog (Chlamydomonas). (1257 aa)
LOC103021477Zinc finger, AN1-type domain 5a. (213 aa)
hhipHedgehog interacting protein. (693 aa)
LOC103046321Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b. (408 aa)
LOC103042886Cholinergic receptor, nicotinic, alpha 1 (muscle). (481 aa)
LOC103033204Si:dkey-49n23.1; Belongs to the semaphorin family. (752 aa)
ENSAMXP00000040343Tsukushi small leucine rich proteoglycan homolog (Xenopus laevis). (342 aa)
OTOROtoraplin. (138 aa)
mmachcMetabolism of cobalamin associated C. (256 aa)
hoxd3Homeobox D3a. (394 aa)
ENSAMXP00000041750Uncharacterized protein. (104 aa)
Rab33bRAB33B, member RAS oncogene family a. (239 aa)
ENSAMXP00000042910Uncharacterized protein. (248 aa)
ENSAMXP00000043285Caspase a; Belongs to the peptidase C14A family. (386 aa)
anxa6Annexin. (667 aa)
IlvblIlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family. (621 aa)
LOC103029459Sharpin and rbck1 related. (725 aa)
LOC103039097Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family. (408 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
rap1bRAP1B, member of RAS oncogene family. (184 aa)
wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
LOC103029147Distal-less homeobox 4b. (231 aa)
dlx5Distal-less homeobox 5a. (276 aa)
ext2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (720 aa)
LOC103042410Cysteine-serine-rich nuclear protein 1b. (580 aa)
RING1Ring finger protein 1. (377 aa)
foxn3Forkhead box N3. (452 aa)
LOC103030680Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. (898 aa)
dlx3Distal-less homeobox 3b. (265 aa)
LOC103026589Fras1 related extracellular matrix 1b. (2158 aa)
pex7Peroxisomal biogenesis factor 7. (319 aa)
hoxc9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (259 aa)
LOC103029481Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (208 aa)
LOC103038759Golgi glycoprotein 1b. (1147 aa)
Alx1ALX homeobox 1. (317 aa)
sp5Sp5 transcription factor a. (374 aa)
ENSAMXP00000049034RRM domain-containing protein. (82 aa)
LOC103046764Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC103041475Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
hoxa3Homeobox A4a. (416 aa)
mef2dMyocyte enhancer factor 2d. (571 aa)
LOC103029799Zgc:113363. (250 aa)
gata3GATA binding protein 3. (442 aa)
fstFollistatin a. (347 aa)
ENSAMXP00000051962LEO1 homolog, Paf1/RNA polymerase II complex component. (584 aa)
rbm24RNA binding motif protein 24a. (250 aa)
ENSAMXP00000053491Uncharacterized protein. (237 aa)
zfand5Zinc finger, AN1-type domain 5b. (209 aa)
ALX3ALX homeobox 3. (359 aa)
rap1aRAP1A, member of RAS oncogene family a. (195 aa)
pitx2Homeobox protein. (300 aa)
LOC103043058Lysyl oxidase-like 3b. (796 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.