STRINGSTRING
LOC103036428 LOC103036428 lrp6 lrp6 W5K317_ASTMX W5K317_ASTMX tgfb1 tgfb1 Lrrk1 Lrrk1 pdlim7 pdlim7 NOX4 NOX4 atg5 atg5 Lrp5 Lrp5 Bax Bax Cthrc1 Cthrc1 W5KF41_ASTMX W5KF41_ASTMX LOC103047816 LOC103047816 cspg4 cspg4 Tbx5 Tbx5 LOC103024607 LOC103024607 acp5 acp5 W5KXV1_ASTMX W5KXV1_ASTMX LOC103040857 LOC103040857 tgfb3 tgfb3 crb1 crb1 plg plg LOC103025789 LOC103025789 ncdn ncdn Bmpr2 Bmpr2 ENSAMXP00000030428 ENSAMXP00000030428 rspo3 rspo3 LOC107197257 LOC107197257 LOC103042872 LOC103042872 ENSAMXP00000032465 ENSAMXP00000032465 ENSAMXP00000033131 ENSAMXP00000033131 LOC103045871 LOC103045871 spp2 spp2 ENSAMXP00000035483 ENSAMXP00000035483 sema3c sema3c ENSAMXP00000039101 ENSAMXP00000039101 wnt16 wnt16 F2R F2R f2r f2r SRC SRC ENSAMXP00000047395 ENSAMXP00000047395 elf3 elf3 LOC103041475 LOC103041475 ENSAMXP00000049817 ENSAMXP00000049817 LOC103038924 LOC103038924 ENSAMXP00000051608 ENSAMXP00000051608 LOC103036258 LOC103036258 ENSAMXP00000052402 ENSAMXP00000052402
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103036428Ephrin-A2b; Belongs to the ephrin family. (206 aa)
lrp6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1618 aa)
W5K317_ASTMXUncharacterized protein. (678 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Lrrk1Leucine-rich repeat kinase 1. (1976 aa)
pdlim7PDZ and LIM domain 7. (509 aa)
NOX4NADPH oxidase 4. (481 aa)
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
Lrp5Low density lipoprotein receptor-related protein 5. (1518 aa)
BaxBCL2 associated X, apoptosis regulator a. (190 aa)
Cthrc1Collagen triple helix repeat containing 1a. (268 aa)
W5KF41_ASTMXLeucine-rich repeat containing G protein-coupled receptor 4. (937 aa)
LOC103047816Zgc:153993. (204 aa)
cspg4Chondroitin sulfate proteoglycan 4. (2310 aa)
Tbx5T-box transcription factor 5a. (522 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
acp5Tartrate-resistant acid phosphatase type 5. (334 aa)
W5KXV1_ASTMXCrumbs cell polarity complex component 2b. (1012 aa)
LOC103040857Si:dkeyp-41f9.3. (2410 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
crb1Crumbs cell polarity complex component 1. (1425 aa)
plgPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (816 aa)
LOC103025789Si:dkey-193c22.2. (2396 aa)
ncdnNeurochondrin. (808 aa)
Bmpr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
ENSAMXP00000030428Acid phosphatase 5b, tartrate resistant. (396 aa)
rspo3R-spondin 3. (314 aa)
LOC107197257Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (451 aa)
LOC103042872Insulin-like growth factor binding protein 5a. (270 aa)
ENSAMXP00000032465Kringle domain-containing protein. (105 aa)
ENSAMXP00000033131G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (475 aa)
LOC103045871Collagen triple helix repeat containing 1b. (257 aa)
spp2Secreted phosphoprotein 2. (189 aa)
ENSAMXP00000035483G_PROTEIN_RECEP_F1_2 domain-containing protein. (355 aa)
sema3cSema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (743 aa)
ENSAMXP00000039101Kringle domain-containing protein. (162 aa)
wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
F2RG_PROTEIN_RECEP_F1_2 domain-containing protein. (471 aa)
f2rCoagulation factor II (thrombin) receptor. (414 aa)
SRCTyrosine-protein kinase. (617 aa)
ENSAMXP00000047395Uncharacterized protein. (327 aa)
elf3E74-like factor 3 (ets domain transcription factor, epithelial-specific ). (367 aa)
LOC103041475Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
ENSAMXP00000049817TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (165 aa)
LOC103038924Tyrosine-protein kinase. (551 aa)
ENSAMXP00000051608Tyrosine-protein kinase. (546 aa)
LOC103036258Uncharacterized protein. (1475 aa)
ENSAMXP00000052402TNF superfamily member 11; Belongs to the tumor necrosis factor family. (231 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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