37 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Angptl3	Angiopoietin-like 3. (457 aa)
	fkbp10	Peptidylprolyl isomerase. (562 aa)
	arid2	AT rich interactive domain 2 (ARID, RFX-like). (1711 aa)
	LOC103034004	Peptidylprolyl isomerase. (562 aa)
	LOC103027015	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (393 aa)
	ENSAMXP00000027359	G_PROTEIN_RECEP_F2_4 domain-containing protein. (199 aa)
	LOC103037702	Angiomotin like 2b. (692 aa)
	SRF	Serum response factor. (527 aa)
	Bmpr2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
	apob	Apolipoprotein Ba. (4413 aa)
	LOC107197257	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (451 aa)
	ENSAMXP00000033131	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (475 aa)
	LOC103022606	Zgc:56585; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (280 aa)
	ENSAMXP00000037899	MADS-box domain-containing protein. (356 aa)
	ENSAMXP00000038404	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (636 aa)
	LOC103033399	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (419 aa)
	LOC103035447	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (265 aa)
	ENSAMXP00000040763	Uncharacterized protein. (233 aa)
	LOC103038588	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1295 aa)
	hpgd	15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
	LOC103031260	Apolipoprotein Bb, tandem duplicate 2. (3748 aa)
	nprl3	NPR3-like, GATOR1 complex subunit. (655 aa)
	ENSAMXP00000044743	G_PROTEIN_RECEP_F2_3 domain-containing protein. (88 aa)
	ENSAMXP00000045405	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (437 aa)
	ENSAMXP00000047894	Endothelin 1. (162 aa)
	hey2	Hes-related family bHLH transcription factor with YRPW motif 2. (315 aa)
	LOC103041475	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
	W5K0L4_ASTMX	MADS-box domain-containing protein. (479 aa)
	ENSAMXP00000050439	Calcitonin receptor-like a; Belongs to the G-protein coupled receptor 2 family. (415 aa)
	W5KGH6_ASTMX	Neurofibromin 1b. (2733 aa)
	LOC103044426	Fibrinogen C-terminal domain-containing protein. (454 aa)
	Tal1	T-cell acute lymphocytic leukemia 1. (371 aa)
	LOC103023715	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family. (862 aa)
	amotl2	Angiomotin like 2a. (735 aa)
	prdm1	PR domain containing 1a, with ZNF domain. (755 aa)
	W5K5H8_ASTMX	PR domain containing 1b, with ZNF domain. (499 aa)
	W5KT32_ASTMX	Neurofibromin 1a. (2744 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Angptl3	LOC103031260	ENSAMXP00000010829	ENSAMXP00000043440	Angiopoietin-like 3.	Apolipoprotein Bb, tandem duplicate 2.	0.428
Angptl3	apob	ENSAMXP00000010829	ENSAMXP00000031207	Angiopoietin-like 3.	Apolipoprotein Ba.	0.428
Bmpr2	LOC103041475	ENSAMXP00000030317	ENSAMXP00000049576	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.903
ENSAMXP00000033131	ENSAMXP00000047894	ENSAMXP00000033131	ENSAMXP00000047894	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.978
ENSAMXP00000033131	LOC107197257	ENSAMXP00000033131	ENSAMXP00000032052	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.902
ENSAMXP00000040763	W5K5H8_ASTMX	ENSAMXP00000040763	ENSAMXP00000002839	Uncharacterized protein.	PR domain containing 1b, with ZNF domain.	0.569
ENSAMXP00000045405	ENSAMXP00000050439	ENSAMXP00000045405	ENSAMXP00000050439	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	Calcitonin receptor-like a; Belongs to the G-protein coupled receptor 2 family.	0.901
ENSAMXP00000047894	ENSAMXP00000033131	ENSAMXP00000047894	ENSAMXP00000033131	Endothelin 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.978
ENSAMXP00000047894	LOC107197257	ENSAMXP00000047894	ENSAMXP00000032052	Endothelin 1.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.971
ENSAMXP00000050439	ENSAMXP00000045405	ENSAMXP00000050439	ENSAMXP00000045405	Calcitonin receptor-like a; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.901
LOC103031260	Angptl3	ENSAMXP00000043440	ENSAMXP00000010829	Apolipoprotein Bb, tandem duplicate 2.	Angiopoietin-like 3.	0.428
LOC103031260	LOC103044426	ENSAMXP00000043440	ENSAMXP00000051370	Apolipoprotein Bb, tandem duplicate 2.	Fibrinogen C-terminal domain-containing protein.	0.428
LOC103035447	LOC103038588	ENSAMXP00000040217	ENSAMXP00000000180	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family.	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.966
LOC103038588	LOC103035447	ENSAMXP00000000180	ENSAMXP00000040217	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family.	0.966
LOC103038588	Tal1	ENSAMXP00000000180	ENSAMXP00000054373	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	T-cell acute lymphocytic leukemia 1.	0.522
LOC103038588	hey2	ENSAMXP00000000180	ENSAMXP00000049413	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Hes-related family bHLH transcription factor with YRPW motif 2.	0.408
LOC103041475	Bmpr2	ENSAMXP00000049576	ENSAMXP00000030317	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.903
LOC103044426	LOC103031260	ENSAMXP00000051370	ENSAMXP00000043440	Fibrinogen C-terminal domain-containing protein.	Apolipoprotein Bb, tandem duplicate 2.	0.428
LOC103044426	apob	ENSAMXP00000051370	ENSAMXP00000031207	Fibrinogen C-terminal domain-containing protein.	Apolipoprotein Ba.	0.428
LOC107197257	ENSAMXP00000033131	ENSAMXP00000032052	ENSAMXP00000033131	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.902