138 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W5KL43_ASTMX	Uncharacterized protein. (1909 aa)
	ENSAMXP00000036285	Shootin 1. (435 aa)
	LOC107197401	Layilin b. (358 aa)
	LOC103041420	Microtubule-associated protein 6b. (362 aa)
	layn	Layilin a. (379 aa)
	ENSAMXP00000035169	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family. (735 aa)
	LOC103033969	Drebrin-like a. (488 aa)
	LOC103029682	Sema domain-containing protein; Belongs to the semaphorin family. (718 aa)
	dbnl	Drebrin-like b. (470 aa)
	ENSAMXP00000034556	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
	PAK3	Non-specific serine/threonine protein kinase. (527 aa)
	ENSAMXP00000033583	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; Belongs to the semaphorin family. (327 aa)
	ENSAMXP00000033495	Uncharacterized protein; Belongs to the semaphorin family. (636 aa)
	ENSAMXP00000032761	Uncharacterized protein. (192 aa)
	UST	Uronyl 2-sulfotransferase. (385 aa)
	Zfyve27	Zinc finger, FYVE domain containing 27. (401 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (903 aa)
	ENSAMXP00000030630	T cell lymphoma invasion and metastasis 2b. (470 aa)
	Bmpr2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (913 aa)
	SRF	Serum response factor. (527 aa)
	ENSAMXP00000028926	Microtubule-associated protein 2. (247 aa)
	ENSAMXP00000028909	Sema domain-containing protein. (415 aa)
	ENSAMXP00000027824	Spastin; Belongs to the AAA ATPase family. (548 aa)
	amigo1	Adhesion molecule with Ig-like domain 1. (495 aa)
	amigo3	Adhesion molecule with Ig-like domain 3. (457 aa)
	SLITRK1	SLIT and NTRK like family member 1. (690 aa)
	islr2	Immunoglobulin superfamily containing leucine-rich repeat 2. (713 aa)
	ngf	Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (202 aa)
	W5LQA2_ASTMX	P21 protein (Cdc42/Rac)-activated kinase 2b; Belongs to the protein kinase superfamily. (489 aa)
	W5LPS2_ASTMX	Microtubule-associated protein. (489 aa)
	LOC103033508	Si:ch211-255p10.4. (832 aa)
	ifrd1	Interferon-related developmental regulator 1. (427 aa)
	W5LKC0_ASTMX	Interferon-related developmental regulator 2. (425 aa)
	Plxnb2	Plexin b2a. (1838 aa)
	W5LIL1_ASTMX	Eph receptor B3a. (858 aa)
	LOC103022457	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E; Belongs to the semaphorin family. (1061 aa)
	LOC103043004	Si:ch211-113g11.6; Belongs to the semaphorin family. (637 aa)
	sema7a	Semaphorin 7A; Belongs to the semaphorin family. (645 aa)
	LOC103045671	Si:ch211-129c21.1; Belongs to the semaphorin family. (779 aa)
	W5LE75_ASTMX	Plexin A3. (1197 aa)
	W5LCZ4_ASTMX	Plexin b1a. (2108 aa)
	SEMA4F	Ssemaphorin 4F; Belongs to the semaphorin family. (825 aa)
	PLXND1	Plexin D1. (1744 aa)
	W5LCT9_ASTMX	Uncharacterized protein; Belongs to the semaphorin family. (777 aa)
	sema3g	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl; Belongs to the semaphorin family. (781 aa)
	Plxnb3	Plexin B3. (1903 aa)
	W5LAK5_ASTMX	Plexin b1b. (2096 aa)
	plxna1	Sema domain-containing protein. (1889 aa)
	W5L6M1_ASTMX	Uncharacterized protein; Belongs to the semaphorin family. (856 aa)
	chodl	Chondrolectin. (303 aa)
	W5L338_ASTMX	Si:dkey-40c11.2. (704 aa)
	Golga4	Golgin A4. (2100 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	W5L0Z5_ASTMX	L1 cell adhesion molecule, paralog a. (1281 aa)
	SEMA6A	Semaphorin 6A; Belongs to the semaphorin family. (566 aa)
	W5KZ30_ASTMX	Sema domain-containing protein. (972 aa)
	LOC103025551	Uncharacterized protein; Belongs to the semaphorin family. (884 aa)
	Adnp	Activity-dependent neuroprotector homeobox b. (1073 aa)
	W5KTW0_ASTMX	Uncharacterized protein. (394 aa)
	W5KTU8_ASTMX	Uncharacterized protein; Belongs to the semaphorin family. (865 aa)
	W5KT95_ASTMX	Si:dkey-16p21.7. (663 aa)
	LOC103023715	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family. (862 aa)
	Cntn2	Contactin 2. (996 aa)
	LOC103043830	Ephrin-A1a; Belongs to the ephrin family. (224 aa)
	W5KQ81_ASTMX	Disco-interacting protein 2 homolog Cb. (1575 aa)
	W5KPU5_ASTMX	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb; Belongs to the semaphorin family. (759 aa)
	stk11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (437 aa)
	ulk1	Unc-51 like autophagy activating kinase 1. (1021 aa)
	tiam1	T cell lymphoma invasion and metastasis 1a. (1633 aa)
	LOC103023032	Cyclin-dependent kinase-like 5. (1111 aa)
	W5KJY9_ASTMX	BR serine/threonine kinase 2b. (651 aa)
	W5KI83_ASTMX	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (749 aa)
	W5KHK9_ASTMX	Drebrin 1. (497 aa)
	W5KGH2_ASTMX	Receptor protein-tyrosine kinase. (953 aa)
	W5KG74_ASTMX	Eph receptor A4, like. (947 aa)
	LOC103041710	Activity-dependent neuroprotector homeobox a. (1028 aa)
	LOC103046088	Si:ch73-40a2.1. (882 aa)
	W5KDT9_ASTMX	Fibronectin 1a. (2159 aa)
	Dip2c	Disco-interacting protein 2 homolog Ca. (1500 aa)
	W5KB52_ASTMX	Disco-interacting protein 2 homolog Ba. (1470 aa)
	ret	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1113 aa)
	LOC103026658	Plexin A1a. (1899 aa)
	LOC103030601	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (228 aa)
	W5K6Z6_ASTMX	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba; Belongs to the semaphorin family. (518 aa)
	tnr	Tenascin R (restrictin, janusin). (1348 aa)
	W5K366_ASTMX	T cell lymphoma invasion and metastasis 1b. (639 aa)
	W5K2Q0_ASTMX	Uncharacterized protein. (879 aa)
	W5K1E9_ASTMX	Plexin A2. (1888 aa)
	W5K0L4_ASTMX	MADS-box domain-containing protein. (479 aa)
	sema3d	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (787 aa)
	sema3a	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family. (780 aa)
	sema3e	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; Belongs to the semaphorin family. (764 aa)
	W5JYH4_ASTMX	Unc-51 like autophagy activating kinase 1a. (802 aa)
	W5JXV7_ASTMX	Disco-interacting protein 2 homolog A. (1430 aa)
	ENSAMXP00000036539	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A. (379 aa)
	sema3c	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (743 aa)
	Ist1	IST1 factor associated with ESCRT-III. (405 aa)
	ryk	Receptor like tyrosine kinase. (627 aa)
	ENSAMXP00000037899	MADS-box domain-containing protein. (356 aa)
	ENSAMXP00000038848	NMDA receptor synaptonuclear signaling and neuronal migration factor a. (585 aa)
	Plxna4	Plexin A4. (1896 aa)
	LOC103040923	Semaphorin 4e; Belongs to the semaphorin family. (751 aa)
	LOC103033204	Si:dkey-49n23.1; Belongs to the semaphorin family. (752 aa)
	Rnd2	Rho family GTPase 2. (234 aa)
	sema5a	Sema domain-containing protein. (1072 aa)
	anapc2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (817 aa)
	ENSAMXP00000041224	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (295 aa)
	LOC103023138	Microtubule-associated protein. (735 aa)
	rtn4r	Reticulon 4 receptor. (470 aa)
	ENSAMXP00000042301	Microtubule-associated protein. (341 aa)
	LOC103043578	Microtubule-associated protein 6a. (463 aa)
	ENSAMXP00000042627	Protein kinase domain-containing protein. (92 aa)
	ENSAMXP00000042655	Ig-like domain-containing protein. (492 aa)
	rufy3	RUN and FYVE domain containing 3. (670 aa)
	sema4b	Sema domain-containing protein; Belongs to the semaphorin family. (833 aa)
	LOC103044253	Disco-interacting protein 2 homolog Bb. (1617 aa)
	LOC103030680	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. (898 aa)
	ENSAMXP00000047193	Uncharacterized protein. (166 aa)
	sema6d	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like; Belongs to the semaphorin family. (1073 aa)
	ENSAMXP00000047885	Uncharacterized protein. (1235 aa)
	ENSAMXP00000047983	NMDA receptor synaptonuclear signaling and neuronal migration factor b. (577 aa)
	LOC103040945	Kell metallo-endopeptidase (Kell blood group). (769 aa)
	LOC103039147	Spartin b. (611 aa)
	LOC103026264	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (800 aa)
	ENSAMXP00000049134	Non-specific serine/threonine protein kinase. (523 aa)
	LOC103023627	Meteorin like, glial cell differentiation regulator b. (310 aa)
	ulk2	Unc-51 like autophagy activating kinase 2. (1040 aa)
	LOC103041475	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
	ENSAMXP00000049950	Sema domain-containing protein. (1875 aa)
	Sema5b	Sema domain-containing protein. (1047 aa)
	ENSAMXP00000051206	Plexin C1. (600 aa)
	ust	Uronyl 2-sulfotransferase a. (404 aa)
	LOC103021450	Ephrin-A1b; Belongs to the ephrin family. (233 aa)
	ENSAMXP00000052670	Protein kinase domain-containing protein. (246 aa)
	ENSAMXP00000053585	Uncharacterized protein. (641 aa)
	tiam2	T cell lymphoma invasion and metastasis 2a. (1743 aa)
	ENSAMXP00000054922	Non-specific serine/threonine protein kinase. (612 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bmpr2	LOC103041475	ENSAMXP00000030317	ENSAMXP00000049576	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.903
CDH2	LOC103030680	ENSAMXP00000031306	ENSAMXP00000046775	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins.	0.901
Cntn2	ENSAMXP00000047885	ENSAMXP00000010185	ENSAMXP00000047885	Contactin 2.	Uncharacterized protein.	0.672
Cntn2	W5L0Z5_ASTMX	ENSAMXP00000010185	ENSAMXP00000013507	Contactin 2.	L1 cell adhesion molecule, paralog a.	0.965
ENSAMXP00000027824	Ist1	ENSAMXP00000027824	ENSAMXP00000037519	Spastin; Belongs to the AAA ATPase family.	IST1 factor associated with ESCRT-III.	0.892
ENSAMXP00000027824	Zfyve27	ENSAMXP00000027824	ENSAMXP00000031937	Spastin; Belongs to the AAA ATPase family.	Zinc finger, FYVE domain containing 27.	0.551
ENSAMXP00000028909	ENSAMXP00000033495	ENSAMXP00000028909	ENSAMXP00000033495	Sema domain-containing protein.	Uncharacterized protein; Belongs to the semaphorin family.	0.605
ENSAMXP00000028909	ENSAMXP00000033583	ENSAMXP00000028909	ENSAMXP00000033583	Sema domain-containing protein.	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; Belongs to the semaphorin family.	0.465
ENSAMXP00000028909	ENSAMXP00000035169	ENSAMXP00000028909	ENSAMXP00000035169	Sema domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family.	0.548
ENSAMXP00000028909	ENSAMXP00000036539	ENSAMXP00000028909	ENSAMXP00000036539	Sema domain-containing protein.	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A.	0.490
ENSAMXP00000028909	LOC103022457	ENSAMXP00000028909	ENSAMXP00000019444	Sema domain-containing protein.	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E; Belongs to the semaphorin family.	0.465
ENSAMXP00000028909	LOC103023715	ENSAMXP00000028909	ENSAMXP00000010642	Sema domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	0.548
ENSAMXP00000028909	LOC103025551	ENSAMXP00000028909	ENSAMXP00000012541	Sema domain-containing protein.	Uncharacterized protein; Belongs to the semaphorin family.	0.459
ENSAMXP00000028909	LOC103026264	ENSAMXP00000028909	ENSAMXP00000049089	Sema domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family.	0.409
ENSAMXP00000028909	LOC103029682	ENSAMXP00000028909	ENSAMXP00000034786	Sema domain-containing protein.	Sema domain-containing protein; Belongs to the semaphorin family.	0.538
ENSAMXP00000028909	LOC103040923	ENSAMXP00000028909	ENSAMXP00000039592	Sema domain-containing protein.	Semaphorin 4e; Belongs to the semaphorin family.	0.540
ENSAMXP00000028909	LOC103043004	ENSAMXP00000028909	ENSAMXP00000019339	Sema domain-containing protein.	Si:ch211-113g11.6; Belongs to the semaphorin family.	0.605
ENSAMXP00000028909	LOC103045671	ENSAMXP00000028909	ENSAMXP00000018212	Sema domain-containing protein.	Si:ch211-129c21.1; Belongs to the semaphorin family.	0.540
ENSAMXP00000028909	SEMA4D	ENSAMXP00000028909	ENSAMXP00000029458	Sema domain-containing protein.	Semaphorin 4D; Belongs to the semaphorin family.	0.540
ENSAMXP00000028909	SEMA4F	ENSAMXP00000028909	ENSAMXP00000017705	Sema domain-containing protein.	Ssemaphorin 4F; Belongs to the semaphorin family.	0.459