109 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pin1	Peptidyl-prolyl cis-trans isomerase. (158 aa)
	phb	Prohibitin. (271 aa)
	camlg	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (282 aa)
	plpp3	Phospholipid phosphatase 3. (313 aa)
	LOC103025033	Apolipoprotein A-Ia. (254 aa)
	LOC103030866	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (249 aa)
	hypk	Huntingtin interacting protein K. (121 aa)
	LOC103021450	Ephrin-A1b; Belongs to the ephrin family. (233 aa)
	ENSAMXP00000051023	Uncharacterized protein. (245 aa)
	ENSAMXP00000050586	SWIM-type zinc finger 7 associated protein 1. (280 aa)
	LOC103030385	Clusterin; Belongs to the clusterin family. (461 aa)
	Prkn	Parkin RBR E3 ubiquitin protein ligase. (417 aa)
	cct2	Chaperonin containing TCP1, subunit 2 (beta). (535 aa)
	LOC103031835	Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (323 aa)
	LOC103047026	acidPPc domain-containing protein. (309 aa)
	TMEM19	Transmembrane protein 19. (336 aa)
	tti2	TELO2 interacting protein 2. (500 aa)
	chp1	Calcineurin-like EF-hand protein 1. (194 aa)
	LOC103038069	Wolfram syndrome 1b (wolframin). (908 aa)
	hip1	Huntingtin interacting protein 1. (1048 aa)
	LOC103044362	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (276 aa)
	naa15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit a. (867 aa)
	Trim44	Tripartite motif containing 44. (272 aa)
	dnlz	DNL-type zinc finger. (192 aa)
	LOC103039651	Zinc finger protein 207, b. (420 aa)
	LOC103026173	Apolipoprotein A-Ib. (260 aa)
	ENSAMXP00000041969	Uncharacterized protein. (261 aa)
	ENSAMXP00000041912	Tescalcin b. (217 aa)
	lamp1	Lysosomal associated membrane protein 1a. (411 aa)
	pink1	PTEN induced kinase 1. (571 aa)
	LOC103046346	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
	Atf7ip	Activating transcription factor 7 interacting protein. (838 aa)
	LOC103021556	Protein kinase domain-containing protein. (1202 aa)
	ENSAMXP00000040318	Granulin a. (872 aa)
	LOC103036702	Si:dkey-217d24.6. (1069 aa)
	LOC103035699	Huntingtin interacting protein 1 related b. (1073 aa)
	rab21	RAB21, member RAS oncogene family. (220 aa)
	mfsd1	Major facilitator superfamily domain containing 1. (516 aa)
	usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1126 aa)
	LOC103028651	Transmembrane protein 88 b. (227 aa)
	sav1	Salvador family WW domain containing protein 1. (405 aa)
	Cog3	Component of oligomeric golgi complex 3. (864 aa)
	hps4	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (661 aa)
	hsp90ab1	Heat shock protein 90, alpha (cytosolic), class B member 1. (725 aa)
	LOC103039045	Zinc finger protein 207, a. (468 aa)
	LOC103041091	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	cdc37	Cell division cycle 37. (390 aa)
	pex19	Peroxisomal biogenesis factor 19. (284 aa)
	mul1	Mitochondrial E3 ubiquitin protein ligase 1b. (352 aa)
	ENSAMXP00000035399	Uncharacterized protein. (240 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (840 aa)
	ENSAMXP00000035084	Uncharacterized protein. (255 aa)
	MSX1	Msh homeobox 1. (201 aa)
	W5LE99_ASTMX	Syntaxin binding protein 4. (787 aa)
	gtpbp4	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (633 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	ENSAMXP00000030654	Si:ch211-194b1.1. (1805 aa)
	apopt1	Cytochrome c oxidase assembly factor 8. (195 aa)
	LOC103021444	Lysosomal-associated membrane protein 2. (380 aa)
	ENSAMXP00000029050	Tetraspanin. (206 aa)
	atf7ip2	Activating transcription factor 7 interacting protein 2. (347 aa)
	Tesc	Tescalcin a. (203 aa)
	cct5	Chaperonin containing TCP1, subunit 5 (epsilon). (541 aa)
	W5LMZ7_ASTMX	AP2 associated kinase 1b. (452 aa)
	LOC103024139	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (731 aa)
	LOC103025751	BCL2 associated athanogene 6. (1241 aa)
	W5LL32_ASTMX	Transmembrane protein 88 a. (246 aa)
	LOC103046308	Granulin b. (750 aa)
	LOC103032832	Cell division cycle 37-like 1. (363 aa)
	mtmr9	Myotubularin related protein 9. (549 aa)
	W5LHV8_ASTMX	Zgc:154055. (565 aa)
	cct3	T-complex protein 1 subunit gamma. (541 aa)
	W5LFW1_ASTMX	Apobec1 complementation factor. (584 aa)
	clu	Clusterin; Belongs to the clusterin family. (451 aa)
	tsc1	TSC complex subunit 1a. (1148 aa)
	LOC103034507	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (425 aa)
	glmp	Glycosylated lysosomal membrane protein. (398 aa)
	sugt1	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (326 aa)
	bag2	BCL2 associated athanogene 2. (209 aa)
	nop53	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (455 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (321 aa)
	LOC103027319	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (423 aa)
	W5L481_ASTMX	Uncharacterized protein. (390 aa)
	ep300	E1A binding protein p300 b. (2652 aa)
	otud3	OTU deubiquitinase 3. (359 aa)
	Cog7	Component of oligomeric golgi complex 7. (752 aa)
	W5JZW3_ASTMX	Tetraspanin. (357 aa)
	bag5	BCL2 associated athanogene 5. (495 aa)
	LOC103027970	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (478 aa)
	chek2	Checkpoint kinase 2. (516 aa)
	park7	Parkinson protein 7. (189 aa)
	W5K912_ASTMX	Wolfram syndrome 1a (wolframin). (542 aa)
	marchf7	Membrane-associated ring finger (C3HC4) 7. (765 aa)
	pex6	Peroxisomal biogenesis factor 6. (1132 aa)
	bag3	BCL2 associated athanogene 3. (527 aa)
	Nlk	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (515 aa)
	LOC103035563	N(alpha)-acetyltransferase 15, NatA auxiliary subunit b. (865 aa)
	bag4	BCL2 associated athanogene 4. (403 aa)
	LOC103043075	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (285 aa)
	W5KIL9_ASTMX	Clusterin; Belongs to the clusterin family. (407 aa)
	cryab	Crystallin, alpha B, b; Belongs to the small heat shock protein (HSP20) family. (172 aa)
	LOC103044365	E1A binding protein p300 a. (2671 aa)
	W5KLK9_ASTMX	Im:7160594. (442 aa)
	W5KMM6_ASTMX	TSC complex subunit 1b. (1211 aa)
	LOC103043830	Ephrin-A1a; Belongs to the ephrin family. (224 aa)
	Telo2	TEL2, telomere maintenance 2, homolog (S. cerevisiae). (837 aa)
	tspan1	Tetraspanin. (241 aa)
	Bag6	BCL2 associated athanogene 6, like. (1193 aa)
	usp13	Ubiquitin carboxyl-terminal hydrolase. (859 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cog3	Cog7	ENSAMXP00000037551	ENSAMXP00000012306	Component of oligomeric golgi complex 3.	Component of oligomeric golgi complex 7.	0.996
Cog3	pex6	ENSAMXP00000037551	ENSAMXP00000004817	Component of oligomeric golgi complex 3.	Peroxisomal biogenesis factor 6.	0.424
Cog7	Cog3	ENSAMXP00000012306	ENSAMXP00000037551	Component of oligomeric golgi complex 7.	Component of oligomeric golgi complex 3.	0.996
ENSAMXP00000040318	lamp1	ENSAMXP00000040318	ENSAMXP00000041253	Granulin a.	Lysosomal associated membrane protein 1a.	0.425
LOC103021444	LOC103024139	ENSAMXP00000030439	ENSAMXP00000021194	Lysosomal-associated membrane protein 2.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	0.421
LOC103021444	W5KMM6_ASTMX	ENSAMXP00000030439	ENSAMXP00000008838	Lysosomal-associated membrane protein 2.	TSC complex subunit 1b.	0.421
LOC103021444	hsp90ab1	ENSAMXP00000030439	ENSAMXP00000036834	Lysosomal-associated membrane protein 2.	Heat shock protein 90, alpha (cytosolic), class B member 1.	0.421
LOC103021444	lamp1	ENSAMXP00000030439	ENSAMXP00000041253	Lysosomal-associated membrane protein 2.	Lysosomal associated membrane protein 1a.	0.926
LOC103021444	tsc1	ENSAMXP00000030439	ENSAMXP00000016575	Lysosomal-associated membrane protein 2.	TSC complex subunit 1a.	0.421
LOC103021556	LOC103035699	ENSAMXP00000040339	ENSAMXP00000039870	Protein kinase domain-containing protein.	Huntingtin interacting protein 1 related b.	0.615
LOC103021556	hip1	ENSAMXP00000040339	ENSAMXP00000045458	Protein kinase domain-containing protein.	Huntingtin interacting protein 1.	0.614
LOC103024139	LOC103021444	ENSAMXP00000021194	ENSAMXP00000030439	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Lysosomal-associated membrane protein 2.	0.421
LOC103024139	LOC103032832	ENSAMXP00000021194	ENSAMXP00000020101	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Cell division cycle 37-like 1.	0.931
LOC103024139	LOC103041091	ENSAMXP00000021194	ENSAMXP00000036178	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Glyceraldehyde-3-phosphate dehydrogenase.	0.456
LOC103024139	LOC103044365	ENSAMXP00000021194	ENSAMXP00000007693	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	E1A binding protein p300 a.	0.517
LOC103024139	Nlk	ENSAMXP00000021194	ENSAMXP00000005365	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.463
LOC103024139	Prkn	ENSAMXP00000021194	ENSAMXP00000049615	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Parkin RBR E3 ubiquitin protein ligase.	0.540
LOC103024139	bag3	ENSAMXP00000021194	ENSAMXP00000004842	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	BCL2 associated athanogene 3.	0.461
LOC103024139	cct2	ENSAMXP00000021194	ENSAMXP00000049423	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Chaperonin containing TCP1, subunit 2 (beta).	0.725
LOC103024139	cct3	ENSAMXP00000021194	ENSAMXP00000019003	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	T-complex protein 1 subunit gamma.	0.701