(30 nodes) Endocrine process network (Astyanax mexicanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103043104	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (444 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (526 aa)
	W5KA79_ASTMX	Corin, serine peptidase. (842 aa)
	ace	Angiotensin-converting enzyme. (1288 aa)
	serpinf2	SERPIN domain-containing protein; Belongs to the serpin family. (470 aa)
	tmf1	TATA element modulatory factor 1. (1161 aa)
	agt	Angiotensinogen; Belongs to the serpin family. (456 aa)
	LOC103038005	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
	Enpep	Aminopeptidase. (944 aa)
	LOC103045451	Arginine vasopressin receptor 2a, duplicate b. (545 aa)
	LOC103024566	Arginine vasopressin receptor 1Ab. (409 aa)
	W5LPF6_ASTMX	Selenoprotein M. (145 aa)
	LOC103027843	Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family. (370 aa)
	LOC103027188	Angiotensin II receptor, type 1a; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	LOC103046319	SERPIN domain-containing protein; Belongs to the serpin family. (459 aa)
	LOC103043510	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (421 aa)
	LOC103042214	Endothelin 3b. (168 aa)
	ENSAMXP00000030282	Si:dkey-178o16.4. (384 aa)
	LOC103028784	Potassium voltage-gated channel, KQT-like subfamily, member 1.2; Belongs to the potassium channel family. (734 aa)
	LOC103047306	Endothelin 2. (169 aa)
	LOC103040768	Oxytocin receptor like. (377 aa)
	ENSAMXP00000040119	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (404 aa)
	LOC103038368	Uncharacterized protein. (140 aa)
	ENSAMXP00000044990	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (259 aa)
	LOC103033689	G_PROTEIN_RECEP_F1_2 domain-containing protein. (538 aa)
	kcnq1	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (662 aa)
	ENSAMXP00000047894	Endothelin 1. (162 aa)
	avpr1a	Arginine vasopressin receptor 1A; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (398 aa)
	LOC103033855	Oxytocin receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (383 aa)
	LOC103041890	Aquaporin 1a (Colton blood group), tandem duplicate 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (266 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000030282	ENSAMXP00000047894	ENSAMXP00000030282	ENSAMXP00000047894	Si:dkey-178o16.4.	Endothelin 1.	0.598
ENSAMXP00000030282	LOC103038368	ENSAMXP00000030282	ENSAMXP00000044060	Si:dkey-178o16.4.	Uncharacterized protein.	0.501
ENSAMXP00000030282	LOC103042214	ENSAMXP00000030282	ENSAMXP00000029872	Si:dkey-178o16.4.	Endothelin 3b.	0.501
ENSAMXP00000030282	LOC103047306	ENSAMXP00000030282	ENSAMXP00000036002	Si:dkey-178o16.4.	Endothelin 2.	0.434
ENSAMXP00000040119	ENSAMXP00000047894	ENSAMXP00000040119	ENSAMXP00000047894	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.953
ENSAMXP00000040119	LOC103038368	ENSAMXP00000040119	ENSAMXP00000044060	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.938
ENSAMXP00000040119	LOC103042214	ENSAMXP00000040119	ENSAMXP00000029872	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	Endothelin 3b.	0.941
ENSAMXP00000040119	LOC103043104	ENSAMXP00000040119	ENSAMXP00000001895	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.902
ENSAMXP00000040119	LOC103043510	ENSAMXP00000040119	ENSAMXP00000029735	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.901
ENSAMXP00000040119	LOC103047306	ENSAMXP00000040119	ENSAMXP00000036002	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	Endothelin 2.	0.888
ENSAMXP00000040119	agt	ENSAMXP00000040119	ENSAMXP00000009798	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	Angiotensinogen; Belongs to the serpin family.	0.611
ENSAMXP00000047894	ENSAMXP00000030282	ENSAMXP00000047894	ENSAMXP00000030282	Endothelin 1.	Si:dkey-178o16.4.	0.598
ENSAMXP00000047894	ENSAMXP00000040119	ENSAMXP00000047894	ENSAMXP00000040119	Endothelin 1.	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	0.953
ENSAMXP00000047894	LOC103024566	ENSAMXP00000047894	ENSAMXP00000018685	Endothelin 1.	Arginine vasopressin receptor 1Ab.	0.598
ENSAMXP00000047894	LOC103027188	ENSAMXP00000047894	ENSAMXP00000026634	Endothelin 1.	Angiotensin II receptor, type 1a; Belongs to the G-protein coupled receptor 1 family.	0.741
ENSAMXP00000047894	LOC103027843	ENSAMXP00000047894	ENSAMXP00000025711	Endothelin 1.	Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family.	0.741
ENSAMXP00000047894	LOC103033689	ENSAMXP00000047894	ENSAMXP00000045339	Endothelin 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.598
ENSAMXP00000047894	LOC103033855	ENSAMXP00000047894	ENSAMXP00000053082	Endothelin 1.	Oxytocin receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	0.598
ENSAMXP00000047894	LOC103038368	ENSAMXP00000047894	ENSAMXP00000044060	Endothelin 1.	Uncharacterized protein.	0.647
ENSAMXP00000047894	LOC103040768	ENSAMXP00000047894	ENSAMXP00000038921	Endothelin 1.	Oxytocin receptor like.	0.598