(93 nodes) Neuromuscular process network (Astyanax mexicanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAMXP00000043331	Troponin I4a. (205 aa)
	HOMER1	Homer scaffold protein 1. (371 aa)
	W5K1H4_ASTMX	Troponin I4b, tandem duplicate 1. (178 aa)
	ENSAMXP00000041417	ATP/GTP binding protein-like 1. (1078 aa)
	ENSAMXP00000041309	Troponin C type 2 (fast). (200 aa)
	LOC103043375	Titin-cap (telethonin). (179 aa)
	STAC3	SH3 and cysteine rich domain 3. (344 aa)
	Stac	SH3 and cysteine rich domain. (361 aa)
	abl1	Tyrosine-protein kinase. (1107 aa)
	ENSAMXP00000039520	Coiled-coil domain containing 78. (461 aa)
	ENSAMXP00000039450	Uncharacterized protein. (120 aa)
	pou4f2	POU domain protein. (423 aa)
	LOC103043231	GTP cyclohydrolase 2. (241 aa)
	LOC103038576	SH3 and multiple ankyrin repeat domains 3b. (1639 aa)
	Hexb	Beta-hexosaminidase. (590 aa)
	LOC103035007	Troponin I type 2a (skeletal, fast), tandem duplicate 1. (193 aa)
	TNNC1	Uncharacterized protein. (161 aa)
	cln8	CLN8 transmembrane ER and ERGIC protein. (288 aa)
	ENSAMXP00000035269	CAP-ZIP_m domain-containing protein. (323 aa)
	gbx1	Gastrulation brain homeobox 1. (322 aa)
	glrb	Glycine receptor, beta b; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (505 aa)
	LOC103032320	Homeobox C10a. (348 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (470 aa)
	ENSAMXP00000033131	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (475 aa)
	LOC103044939	Si:rp71-17i16.4. (213 aa)
	LOC107197257	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (451 aa)
	ENSAMXP00000031129	Uncharacterized protein. (199 aa)
	pou4f1	POU domain protein. (380 aa)
	gm2a	GM2 ganglioside activator. (198 aa)
	LOC103025075	Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino. (256 aa)
	LOC103046134	Proenkephalin a. (242 aa)
	GRIN3A	Glutamate ionotropic receptor NMDA type subunit 3A. (1144 aa)
	LOC103034366	Troponin I type 2a (skeletal, fast), tandem duplicate 4. (176 aa)
	vti1a	Vesicle transport through interaction with t-SNAREs 1A. (224 aa)
	Fxn	Frataxin. (125 aa)
	LOC103041735	Glycine receptor, beta a; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (502 aa)
	opa3	Outer mitochondrial membrane lipid metabolism regulator OPA3. (156 aa)
	GPR88	G protein-coupled receptor 88. (423 aa)
	slitrk6	SLIT and NTRK-like family, member 6. (830 aa)
	W5LRA5_ASTMX	Uncharacterized protein. (157 aa)
	LOC103022042	Troponin I type 2b (skeletal, fast), tandem duplicate 1. (176 aa)
	W5LN37_ASTMX	SH3 and multiple ankyrin repeat domains 2a. (1756 aa)
	arpp21	cAMP-regulated phosphoprotein, 21. (689 aa)
	W5LM01_ASTMX	Solute carrier family 17 member 8. (590 aa)
	igdcc3	Immunoglobulin superfamily, DCC subclass, member 3. (804 aa)
	ENSAMXP00000051792	Si:ch211-57n23.4. (710 aa)
	LOC103046826	Glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb. (1334 aa)
	LOC103037334	Zgc:153184. (297 aa)
	Prkn	Parkin RBR E3 ubiquitin protein ligase. (417 aa)
	lrrc45	Leucine rich repeat containing 45. (674 aa)
	STAC2	SH3 and cysteine rich domain 2. (377 aa)
	ENSAMXP00000051590	Uncharacterized protein. (180 aa)
	LOC103029055	Dynactin domain-containing protein. (1226 aa)
	LOC103039147	Spartin b. (611 aa)
	LOC103036986	PNKD metallo-beta-lactamase domain containing. (361 aa)
	LOC103025257	Glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca. (1424 aa)
	mecp2	Methyl CpG binding protein 2. (612 aa)
	ucn	Urotensin 1. (207 aa)
	ENSAMXP00000046482	Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b. (1415 aa)
	LOC103021519	Troponin C type 1b (slow). (214 aa)
	gch1	GTP cyclohydrolase 1. (267 aa)
	ENSAMXP00000045469	SH3 and multiple ankyrin repeat domains 1. (1896 aa)
	r3hdm1	R3H domain containing 1. (1140 aa)
	Tnni1	Troponin I type 1b (skeletal, slow). (170 aa)
	LOC103040208	Homer scaffold protein 1b. (398 aa)
	Grin2b	Uncharacterized protein. (1548 aa)
	vps54	VPS54 subunit of GARP complex. (1007 aa)
	get1	Guided entry of tail-anchored proteins factor 1. (204 aa)
	ENSAMXP00000053577	Uncharacterized protein. (173 aa)
	W5LHC5_ASTMX	Glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b. (1511 aa)
	dctn1	Dynactin 1b. (1246 aa)
	LOC103046771	Beta-hexosaminidase. (533 aa)
	W5LDQ2_ASTMX	Proenkephalin b. (240 aa)
	W5LD01_ASTMX	R3H domain containing 2. (889 aa)
	W5LCS6_ASTMX	Troponin I type 2a (skeletal, fast), tandem duplicate 4. (172 aa)
	W5LCR2_ASTMX	Troponin I2, fast skeletal type. (170 aa)
	Ush1c	Usher syndrome 1C. (586 aa)
	Mycbp2	MYC binding protein 2. (4543 aa)
	W5LBR1_ASTMX	Fer-1 like family member 6. (1723 aa)
	LOC103028321	Synemin, intermediate filament protein; Belongs to the intermediate filament family. (1098 aa)
	W5L9F6_ASTMX	Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1786 aa)
	W5L624_ASTMX	Otoferlin b. (1820 aa)
	drd3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (471 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2518 aa)
	R3HDM1	R3H domain containing 1. (1126 aa)
	agtpbp1	ATP/GTP binding protein 1. (1157 aa)
	LOC103040794	Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a. (1810 aa)
	W5K601_ASTMX	Otoferlin a. (1873 aa)
	Grin2a	Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1294 aa)
	abl2	Tyrosine-protein kinase. (1149 aa)
	tnr	Tenascin R (restrictin, janusin). (1348 aa)
	LOC103038418	Uncharacterized protein. (735 aa)
	Tmem150c	Transmembrane protein 150C. (250 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000033131	LOC107197257	ENSAMXP00000033131	ENSAMXP00000032052	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.902
ENSAMXP00000039450	ENSAMXP00000041309	ENSAMXP00000039450	ENSAMXP00000041309	Uncharacterized protein.	Troponin C type 2 (fast).	0.894
ENSAMXP00000039450	ENSAMXP00000043331	ENSAMXP00000039450	ENSAMXP00000043331	Uncharacterized protein.	Troponin I4a.	0.598
ENSAMXP00000039450	ENSAMXP00000051590	ENSAMXP00000039450	ENSAMXP00000051590	Uncharacterized protein.	Uncharacterized protein.	0.607
ENSAMXP00000039450	LOC103021519	ENSAMXP00000039450	ENSAMXP00000046189	Uncharacterized protein.	Troponin C type 1b (slow).	0.746
ENSAMXP00000039450	LOC103044939	ENSAMXP00000039450	ENSAMXP00000032305	Uncharacterized protein.	Si:rp71-17i16.4.	0.894
ENSAMXP00000039450	TNNC1	ENSAMXP00000039450	ENSAMXP00000036526	Uncharacterized protein.	Uncharacterized protein.	0.746
ENSAMXP00000039450	Tnni1	ENSAMXP00000039450	ENSAMXP00000044317	Uncharacterized protein.	Troponin I type 1b (skeletal, slow).	0.670
ENSAMXP00000039450	W5K1H4_ASTMX	ENSAMXP00000039450	ENSAMXP00000042011	Uncharacterized protein.	Troponin I4b, tandem duplicate 1.	0.600
ENSAMXP00000039450	W5LRA5_ASTMX	ENSAMXP00000039450	ENSAMXP00000025410	Uncharacterized protein.	Uncharacterized protein.	0.746
ENSAMXP00000041309	ENSAMXP00000039450	ENSAMXP00000041309	ENSAMXP00000039450	Troponin C type 2 (fast).	Uncharacterized protein.	0.894
ENSAMXP00000041309	ENSAMXP00000043331	ENSAMXP00000041309	ENSAMXP00000043331	Troponin C type 2 (fast).	Troponin I4a.	0.811
ENSAMXP00000041309	ENSAMXP00000051590	ENSAMXP00000041309	ENSAMXP00000051590	Troponin C type 2 (fast).	Uncharacterized protein.	0.811
ENSAMXP00000041309	LOC103021519	ENSAMXP00000041309	ENSAMXP00000046189	Troponin C type 2 (fast).	Troponin C type 1b (slow).	0.556
ENSAMXP00000041309	LOC103022042	ENSAMXP00000041309	ENSAMXP00000022221	Troponin C type 2 (fast).	Troponin I type 2b (skeletal, fast), tandem duplicate 1.	0.914
ENSAMXP00000041309	LOC103034366	ENSAMXP00000041309	ENSAMXP00000029090	Troponin C type 2 (fast).	Troponin I type 2a (skeletal, fast), tandem duplicate 4.	0.899
ENSAMXP00000041309	LOC103035007	ENSAMXP00000041309	ENSAMXP00000037624	Troponin C type 2 (fast).	Troponin I type 2a (skeletal, fast), tandem duplicate 1.	0.894
ENSAMXP00000041309	TNNC1	ENSAMXP00000041309	ENSAMXP00000036526	Troponin C type 2 (fast).	Uncharacterized protein.	0.550
ENSAMXP00000041309	Tnni1	ENSAMXP00000041309	ENSAMXP00000044317	Troponin C type 2 (fast).	Troponin I type 1b (skeletal, slow).	0.878
ENSAMXP00000041309	W5K1H4_ASTMX	ENSAMXP00000041309	ENSAMXP00000042011	Troponin C type 2 (fast).	Troponin I4b, tandem duplicate 1.	0.811