STRINGSTRING
Runx2 Runx2 LOC103021856 LOC103021856 sema3d sema3d W5K0L4_ASTMX W5K0L4_ASTMX creb3l2 creb3l2 LOC103043405 LOC103043405 LOC103036172 LOC103036172 tgfb1 tgfb1 Eif2ak3 Eif2ak3 sec23a sec23a LOC103042959 LOC103042959 smarcal1 smarcal1 LOC103035562 LOC103035562 itgb8 itgb8 W5KD73_ASTMX W5KD73_ASTMX Rb1 Rb1 Sox6 Sox6 ccn2 ccn2 gnptab gnptab Sox5 Sox5 Ddrgk1 Ddrgk1 W5KN49_ASTMX W5KN49_ASTMX LOC103022868 LOC103022868 LOC103024607 LOC103024607 TBX10 TBX10 W5KUR6_ASTMX W5KUR6_ASTMX dlx2 dlx2 LOC103024223 LOC103024223 W5L0W7_ASTMX W5L0W7_ASTMX W5L312_ASTMX W5L312_ASTMX W5L5T0_ASTMX W5L5T0_ASTMX W5L798_ASTMX W5L798_ASTMX CNMD CNMD ecm1 ecm1 tgfbr2 tgfbr2 W5LMI9_ASTMX W5LMI9_ASTMX Trip11 Trip11 LOC103025695 LOC103025695 LOC103043606 LOC103043606 LOC103042468 LOC103042468 CCN3 CCN3 dlx1 dlx1 LOC103042774 LOC103042774 alcam alcam SRF SRF ENSAMXP00000029247 ENSAMXP00000029247 LOC103042113 LOC103042113 LOC103044743 LOC103044743 ENSAMXP00000029564 ENSAMXP00000029564 LOC111193684 LOC111193684 ccn1 ccn1 fgf4 fgf4 Bmpr2 Bmpr2 bmp6 bmp6 LOC103033177 LOC103033177 wnt7a wnt7a bmp5 bmp5 bmpr1b bmpr1b CDH2 CDH2 FOXC1 FOXC1 fgf6 fgf6 fgf8 fgf8 zmpste24 zmpste24 bbs1 bbs1 LOC103041531 LOC103041531 ENSAMXP00000033840 ENSAMXP00000033840 MSX1 MSX1 uxs1 uxs1 Fgf3 Fgf3 LOC103027213 LOC103027213 LOC103028976 LOC103028976 ENSAMXP00000035854 ENSAMXP00000035854 LOC103043816 LOC103043816 LOC103040552 LOC103040552 LOC103029324 LOC103029324 ENSAMXP00000037899 ENSAMXP00000037899 LOC103028241 LOC103028241 LOC103042886 LOC103042886 ENSAMXP00000040184 ENSAMXP00000040184 LOC103033204 LOC103033204 ENSAMXP00000040343 ENSAMXP00000040343 snai2 snai2 OTOR OTOR sulf1 sulf1 slc10a7 slc10a7 LOC103038627 LOC103038627 ENSAMXP00000042370 ENSAMXP00000042370 anxa6 anxa6 LOC103039097 LOC103039097 LOC103042559 LOC103042559 rap1b rap1b ENSAMXP00000044267 ENSAMXP00000044267 wnt5a wnt5a dlx5 dlx5 ENSAMXP00000044977 ENSAMXP00000044977 ext2 ext2 LOC111190962 LOC111190962 LOC103025122 LOC103025122 bmp4 bmp4 LOC103026929 LOC103026929 LOC103030680 LOC103030680 ENSAMXP00000046843 ENSAMXP00000046843 dlx3 dlx3 ENSAMXP00000047885 ENSAMXP00000047885 ENSAMXP00000047894 ENSAMXP00000047894 LOC103029481 LOC103029481 LOC103025657 LOC103025657 LOC103046764 LOC103046764 LOC103041475 LOC103041475 mef2d mef2d LOC103025967 LOC103025967 mkks mkks wnt7b wnt7b ENSAMXP00000050762 ENSAMXP00000050762 LOC103047576 LOC103047576 ENSAMXP00000053702 ENSAMXP00000053702 rap1a rap1a Bmp7 Bmp7 HAND1 HAND1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Runx2Runt-related transcription factor. (417 aa)
LOC103021856Bone morphogenetic protein 2a. (405 aa)
sema3dSema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (787 aa)
W5K0L4_ASTMXMADS-box domain-containing protein. (479 aa)
creb3l2cAMP responsive element binding protein 3-like 2. (530 aa)
LOC103043405Chondromodulin. (373 aa)
LOC103036172Sorting nexin 19b. (983 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Eif2ak3Eukaryotic translation initiation factor 2-alpha kinase 3. (943 aa)
sec23aProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
LOC103042959Activated leukocyte cell adhesion molecule b. (564 aa)
smarcal1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (885 aa)
LOC103035562BARX homeobox 1. (232 aa)
itgb8Integrin beta; Belongs to the integrin beta chain family. (790 aa)
W5KD73_ASTMXAT rich interactive domain 5A (MRF1-like). (583 aa)
Rb1Retinoblastoma 1. (882 aa)
Sox6SRY-box transcription factor 6. (787 aa)
ccn2Cellular communication network factor 2a. (362 aa)
gnptabN-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1220 aa)
Sox5SRY-box transcription factor 5. (763 aa)
Ddrgk1DDRGK domain containing 1. (148 aa)
W5KN49_ASTMXUncharacterized protein; Belongs to the heparin-binding growth factors family. (67 aa)
LOC103022868RAP1A, member of RAS oncogene family b. (185 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
TBX10T-box transcription factor 10. (196 aa)
W5KUR6_ASTMXPolycystic kidney disease 1a. (4355 aa)
dlx2Dlx2a. (277 aa)
LOC103024223Secreted frizzled-related protein 2 like. (312 aa)
W5L0W7_ASTMXTransmembrane anterior posterior transformation 1b. (553 aa)
W5L312_ASTMXIntraflagellar transport 80 homolog (Chlamydomonas). (768 aa)
W5L5T0_ASTMXForkhead box C1b. (210 aa)
W5L798_ASTMXYes-associated protein 1. (431 aa)
CNMDChondromodulin. (403 aa)
ecm1Extracellular matrix protein 1b. (490 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
W5LMI9_ASTMXT-box transcription factor 1. (417 aa)
Trip11Thyroid hormone receptor interactor 11. (1949 aa)
LOC103025695Extracellular sulfatase. (869 aa)
LOC103043606Uncharacterized protein. (347 aa)
LOC103042468Uncharacterized protein. (347 aa)
CCN3Cellular communication network factor 3. (344 aa)
dlx1Distal-less homeobox 1a. (254 aa)
LOC103042774Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family. (403 aa)
alcamActivated leukocyte cell adhesion molecule a. (565 aa)
SRFSerum response factor. (527 aa)
ENSAMXP00000029247Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
LOC103042113Bone morphogenetic protein 7a. (403 aa)
LOC103044743MARCKS-like 1a. (207 aa)
ENSAMXP00000029564Noggin 3. (201 aa)
LOC111193684Si:ch211-161c3.6. (114 aa)
ccn1Cellular communication network factor 1. (372 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (191 aa)
Bmpr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
bmp6Bone morphogenetic protein 6. (427 aa)
LOC103033177Cytochrome P450, family 26, subfamily b, polypeptide 1; Belongs to the cytochrome P450 family. (511 aa)
wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
bmp5Bone morphogenetic protein 5. (445 aa)
bmpr1bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (903 aa)
FOXC1Forkhead box C1. (541 aa)
fgf6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (470 aa)
bbs1Bardet-Biedl syndrome 1. (588 aa)
LOC103041531Runt-related transcription factor. (449 aa)
ENSAMXP00000033840Hyaluronidase. (431 aa)
MSX1Msh homeobox 1. (201 aa)
uxs1UDP-glucuronate decarboxylase 1. (406 aa)
Fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
LOC103027213Hairy-related 2. (151 aa)
LOC103028976Bone morphogenetic protein 2b. (445 aa)
ENSAMXP00000035854Noggin; Belongs to the noggin family. (209 aa)
LOC103043816RNA polymerase I and III subunit D. (138 aa)
LOC103040552Sulfatase 2b. (1101 aa)
LOC103029324Bone morphogenetic protein 16. (430 aa)
ENSAMXP00000037899MADS-box domain-containing protein. (356 aa)
LOC103028241Runt-related transcription factor. (464 aa)
LOC103042886Cholinergic receptor, nicotinic, alpha 1 (muscle). (481 aa)
ENSAMXP00000040184Epiphycan. (378 aa)
LOC103033204Si:dkey-49n23.1; Belongs to the semaphorin family. (752 aa)
ENSAMXP00000040343Tsukushi small leucine rich proteoglycan homolog (Xenopus laevis). (342 aa)
snai2Snail family zinc finger 2. (259 aa)
OTOROtoraplin. (138 aa)
sulf1Sulfatase 1. (1166 aa)
slc10a7Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (341 aa)
LOC103038627Transmembrane anterior posterior transformation 1a. (591 aa)
ENSAMXP00000042370Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
anxa6Annexin. (667 aa)
LOC103039097Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family. (408 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
rap1bRAP1B, member of RAS oncogene family. (184 aa)
ENSAMXP00000044267Forkhead box Q2. (200 aa)
wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
dlx5Distal-less homeobox 5a. (276 aa)
ENSAMXP00000044977RunxI domain-containing protein. (128 aa)
ext2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (720 aa)
LOC111190962Interleukin 17a/f1. (147 aa)
LOC103025122Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (531 aa)
bmp4TGF_BETA_2 domain-containing protein. (481 aa)
LOC103026929Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
LOC103030680Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. (898 aa)
ENSAMXP00000046843Uncharacterized protein. (683 aa)
dlx3Distal-less homeobox 3b. (265 aa)
ENSAMXP00000047885Uncharacterized protein. (1235 aa)
ENSAMXP00000047894Endothelin 1. (162 aa)
LOC103029481Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (208 aa)
LOC103025657Runt-related transcription factor. (468 aa)
LOC103046764Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC103041475Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
mef2dMyocyte enhancer factor 2d. (571 aa)
LOC103025967Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
mkksMcKusick-Kaufman syndrome. (596 aa)
wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
ENSAMXP00000050762Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (531 aa)
LOC103047576MARCKS-like 1b. (215 aa)
ENSAMXP00000053702Uncharacterized protein. (283 aa)
rap1aRAP1A, member of RAS oncogene family a. (195 aa)
Bmp7Bone morphogenetic protein 7b. (416 aa)
HAND1Heart and neural crest derivatives expressed 1. (157 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.