21 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103035562	BARX homeobox 1. (232 aa)
	TBX10	T-box transcription factor 10. (196 aa)
	smad5	Mothers against decapentaplegic homolog. (464 aa)
	dlx2	Dlx2a. (277 aa)
	LOC103030832	RAD21 cohesin complex component like 1. (550 aa)
	W5LMI9_ASTMX	T-box transcription factor 1. (417 aa)
	rad21	RAD21 cohesin complex component b. (636 aa)
	kctd15	Potassium channel tetramerization domain containing 15. (265 aa)
	ENSAMXP00000027359	G_PROTEIN_RECEP_F2_4 domain-containing protein. (199 aa)
	LOC103025318	NK2 homeobox 5. (313 aa)
	LOC103032053	Potassium channel tetramerization domain containing 15a. (266 aa)
	Bmpr2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
	LOC107197257	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (451 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	LOC103039334	RAD21 cohesin complex component a. (637 aa)
	ENSAMXP00000033131	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (475 aa)
	LOC103046242	Uncharacterized protein. (502 aa)
	nkx3-1	NK3 homeobox 1. (202 aa)
	ENSAMXP00000038404	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (636 aa)
	ENSAMXP00000047894	Endothelin 1. (162 aa)
	LOC103041475	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bmpr2	LOC103041475	ENSAMXP00000030317	ENSAMXP00000049576	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.903
Bmpr2	smad5	ENSAMXP00000030317	ENSAMXP00000011289	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.611
ENSAMXP00000033131	ENSAMXP00000047894	ENSAMXP00000033131	ENSAMXP00000047894	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.978
ENSAMXP00000033131	LOC107197257	ENSAMXP00000033131	ENSAMXP00000032052	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.902
ENSAMXP00000047894	ENSAMXP00000033131	ENSAMXP00000047894	ENSAMXP00000033131	Endothelin 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.978
ENSAMXP00000047894	LOC107197257	ENSAMXP00000047894	ENSAMXP00000032052	Endothelin 1.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.971
ENSAMXP00000047894	fgf8	ENSAMXP00000047894	ENSAMXP00000032559	Endothelin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.568
LOC103025318	fgf8	ENSAMXP00000028592	ENSAMXP00000032559	NK2 homeobox 5.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.446
LOC103030832	LOC103039334	ENSAMXP00000013363	ENSAMXP00000032739	RAD21 cohesin complex component like 1.	RAD21 cohesin complex component a.	0.903
LOC103030832	rad21	ENSAMXP00000013363	ENSAMXP00000021316	RAD21 cohesin complex component like 1.	RAD21 cohesin complex component b.	0.903
LOC103035562	fgf8	ENSAMXP00000004533	ENSAMXP00000032559	BARX homeobox 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.428
LOC103039334	LOC103030832	ENSAMXP00000032739	ENSAMXP00000013363	RAD21 cohesin complex component a.	RAD21 cohesin complex component like 1.	0.903
LOC103039334	rad21	ENSAMXP00000032739	ENSAMXP00000021316	RAD21 cohesin complex component a.	RAD21 cohesin complex component b.	0.900
LOC103041475	Bmpr2	ENSAMXP00000049576	ENSAMXP00000030317	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.903
LOC103041475	smad5	ENSAMXP00000049576	ENSAMXP00000011289	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.611
LOC107197257	ENSAMXP00000033131	ENSAMXP00000032052	ENSAMXP00000033131	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.902
LOC107197257	ENSAMXP00000047894	ENSAMXP00000032052	ENSAMXP00000047894	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.971
dlx2	fgf8	ENSAMXP00000011724	ENSAMXP00000032559	Dlx2a.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.442
fgf8	ENSAMXP00000047894	ENSAMXP00000032559	ENSAMXP00000047894	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Endothelin 1.	0.568
fgf8	LOC103025318	ENSAMXP00000032559	ENSAMXP00000028592	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	NK2 homeobox 5.	0.446