STRINGSTRING
fzd4 fzd4 ret ret LOC103030220 LOC103030220 pde6c pde6c Lrp5 Lrp5 Bax Bax rnf2 rnf2 vax2 vax2 W5KE90_ASTMX W5KE90_ASTMX Prkci Prkci W5KHG4_ASTMX W5KHG4_ASTMX W5KLE1_ASTMX W5KLE1_ASTMX ptf1a ptf1a W5KN59_ASTMX W5KN59_ASTMX Tbx5 Tbx5 Eys Eys Sdk1 Sdk1 pde6a pde6a gdf5 gdf5 LOC103033915 LOC103033915 POC1B POC1B LOC103043088 LOC103043088 W5KXV1_ASTMX W5KXV1_ASTMX Med24 Med24 prpf31 prpf31 MED27 MED27 W5KZC0_ASTMX W5KZC0_ASTMX ift172 ift172 dmbx1 dmbx1 pax6 pax6 Lamb2 Lamb2 ranbp9 ranbp9 W5L531_ASTMX W5L531_ASTMX ttc8 ttc8 W5L5T0_ASTMX W5L5T0_ASTMX W5L798_ASTMX W5L798_ASTMX W5LAF8_ASTMX W5LAF8_ASTMX W5LBA3_ASTMX W5LBA3_ASTMX W5LBA6_ASTMX W5LBA6_ASTMX IGSF22 IGSF22 W5LBC4_ASTMX W5LBC4_ASTMX Ush1c Ush1c W5LDV3_ASTMX W5LDV3_ASTMX crb1 crb1 rpgrip1l rpgrip1l nr2e3 nr2e3 bsg bsg rorb rorb nectin1 nectin1 GPM6A GPM6A gnl3 gnl3 W5LP30_ASTMX W5LP30_ASTMX W5LQ66_ASTMX W5LQ66_ASTMX fjx1 fjx1 zhx2 zhx2 Pomgnt2 Pomgnt2 MAB21L1 MAB21L1 W5LTC8_ASTMX W5LTC8_ASTMX atoh7 atoh7 ENSAMXP00000027435 ENSAMXP00000027435 lmo2 lmo2 alcam alcam trappc11 trappc11 emc3 emc3 ENSAMXP00000029296 ENSAMXP00000029296 LOC103044743 LOC103044743 med1 med1 LOC103027194 LOC103027194 fen1 fen1 Bmpr2 Bmpr2 ttll5 ttll5 rd3 rd3 ENSAMXP00000031142 ENSAMXP00000031142 LOC103036816 LOC103036816 CDH2 CDH2 ENSAMXP00000031417 ENSAMXP00000031417 ENSAMXP00000031658 ENSAMXP00000031658 LOC103028857 LOC103028857 mab21l2 mab21l2 bbs4 bbs4 ENSAMXP00000032034 ENSAMXP00000032034 FOXC1 FOXC1 LOC103035022 LOC103035022 mfrp mfrp fgf8 fgf8 rtn4ip1 rtn4ip1 get1 get1 LOC103047576 LOC103047576 pfdn5 pfdn5 LOC103040507 LOC103040507 ran ran Tatdn1 Tatdn1 ENSAMXP00000052939 ENSAMXP00000052939 dcx dcx LOC103039523 LOC103039523 LOC103036258 LOC103036258 ndp ndp ENSAMXP00000050505 ENSAMXP00000050505 igf2bp1 igf2bp1 LOC103041475 LOC103041475 ENSAMXP00000032674 ENSAMXP00000032674 gpm6a gpm6a LOC103038485 LOC103038485 ENSAMXP00000033445 ENSAMXP00000033445 tbx2 tbx2 Impg2 Impg2 naglu naglu mpp5 mpp5 Fgf3 Fgf3 egr1 egr1 ENSAMXP00000035888 ENSAMXP00000035888 cln8 cln8 Thrb Thrb Mib1 Mib1 fgf2 fgf2 Nphp4 Nphp4 ENSAMXP00000038761 ENSAMXP00000038761 LOC103030186 LOC103030186 LOC103025417 LOC103025417 LOC103032969 LOC103032969 LOC103025442 LOC103025442 tspan12 tspan12 ENSAMXP00000044267 ENSAMXP00000044267 OTX2-2 OTX2-2 LOC103040252 LOC103040252 LOC103043365 LOC103043365 RING1 RING1 ift46 ift46 LOC103030680 LOC103030680 ENSAMXP00000047014 ENSAMXP00000047014 ENSAMXP00000047395 ENSAMXP00000047395 prph2 prph2 usp45 usp45 W5JY90_ASTMX W5JY90_ASTMX W5JYT6_ASTMX W5JYT6_ASTMX W5JZ29_ASTMX W5JZ29_ASTMX lrp6 lrp6 LOC103026996 LOC103026996 W5JZX3_ASTMX W5JZX3_ASTMX W5K0Z5_ASTMX W5K0Z5_ASTMX bves bves nrf1 nrf1 Rs1 Rs1 Fat3 Fat3 W5K317_ASTMX W5K317_ASTMX hps1 hps1 LOC103042959 LOC103042959 LOC103041897 LOC103041897
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (526 aa)
retProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1113 aa)
LOC103030220RPGR interacting protein 1. (1334 aa)
pde6cPhosphodiesterase. (851 aa)
Lrp5Low density lipoprotein receptor-related protein 5. (1518 aa)
BaxBCL2 associated X, apoptosis regulator a. (190 aa)
rnf2Ring finger protein 2. (336 aa)
vax2Ventral anterior homeobox 2. (312 aa)
W5KE90_ASTMXCactin. (706 aa)
PrkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (546 aa)
W5KHG4_ASTMXForkhead box N4. (419 aa)
W5KLE1_ASTMXPeripherin 2-like a. (362 aa)
ptf1aPancreas associated transcription factor 1a. (243 aa)
W5KN59_ASTMXFAT atypical cadherin 3b. (4028 aa)
Tbx5T-box transcription factor 5a. (522 aa)
EysUncharacterized protein. (327 aa)
Sdk1Sidekick cell adhesion molecule 1a. (2060 aa)
pde6aPhosphodiesterase. (863 aa)
gdf5Growth differentiation factor 5. (431 aa)
LOC103033915Orthodenticle homeobox 1. (331 aa)
POC1BPOC1 centriolar protein B. (505 aa)
LOC103043088Membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5); Belongs to the MAGUK family. (713 aa)
W5KXV1_ASTMXCrumbs cell polarity complex component 2b. (1012 aa)
Med24Mediator complex subunit 24. (974 aa)
prpf31PRP31 pre-mRNA processing factor 31 homolog (yeast). (510 aa)
MED27Mediator complex subunit 27. (160 aa)
W5KZC0_ASTMXProtein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. (347 aa)
ift172Intraflagellar transport 172. (1749 aa)
dmbx1Diencephalon/mesencephalon homeobox 1b. (418 aa)
pax6PAX-6 protein. (459 aa)
Lamb2Laminin, beta 2 (laminin S). (1771 aa)
ranbp9RAN binding protein 9. (597 aa)
W5L531_ASTMXUncharacterized protein. (161 aa)
ttc8Tetratricopeptide repeat domain 8. (507 aa)
W5L5T0_ASTMXForkhead box C1b. (210 aa)
W5L798_ASTMXYes-associated protein 1. (431 aa)
W5LAF8_ASTMXPaired box 4. (413 aa)
W5LBA3_ASTMXImmunoglobulin like and fibronectin type III domain containing 1, tandem duplicate 3. (1340 aa)
W5LBA6_ASTMXUncharacterized protein. (1158 aa)
IGSF22Immunoglobulin superfamily member 22. (1340 aa)
W5LBC4_ASTMXImmunoglobulin like and fibronectin type III domain containing 1, tandem duplicate 2. (1325 aa)
Ush1cUsher syndrome 1C. (586 aa)
W5LDV3_ASTMXUncharacterized protein. (2254 aa)
crb1Crumbs cell polarity complex component 1. (1425 aa)
rpgrip1lRPGRIP1 like. (1277 aa)
nr2e3Nuclear receptor subfamily 2, group E, member 3. (427 aa)
bsgBasigin. (394 aa)
rorbRAR-related orphan receptor B. (482 aa)
nectin1Nectin cell adhesion molecule 1b. (504 aa)
GPM6AGlycoprotein M6A. (255 aa)
gnl3Guanine nucleotide binding protein-like 3 (nucleolar). (562 aa)
W5LP30_ASTMXSidekick cell adhesion molecule 2a. (2161 aa)
W5LQ66_ASTMXUncharacterized protein. (477 aa)
fjx1Four-jointed box kinase 1. (396 aa)
zhx2Zinc fingers and homeoboxes 2a. (792 aa)
Pomgnt2Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-). (590 aa)
MAB21L1Mab-21-like 1. (359 aa)
W5LTC8_ASTMXCytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (523 aa)
atoh7Atonal bHLH transcription factor 7. (140 aa)
ENSAMXP00000027435Insulinoma-associated 1a. (419 aa)
lmo2LIM domain only 2 (rhombotin-like 1). (159 aa)
alcamActivated leukocyte cell adhesion molecule a. (565 aa)
trappc11Trafficking protein particle complex 11. (1132 aa)
emc3ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
ENSAMXP00000029296Retinal homeobox gene 3. (190 aa)
LOC103044743MARCKS-like 1a. (207 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1801 aa)
LOC103027194V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (410 aa)
Bmpr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
ttll5Tubulin tyrosine ligase-like family, member 5. (1358 aa)
rd3Retinal degeneration 3, GUCY2D regulator. (216 aa)
ENSAMXP00000031142Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (408 aa)
LOC103036816Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (526 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (903 aa)
ENSAMXP00000031417Uncharacterized protein. (240 aa)
ENSAMXP00000031658Abhydrolase domain containing 12. (467 aa)
LOC103028857Peripherin 2b (retinal degeneration, slow). (343 aa)
mab21l2Mab-21-like 2. (359 aa)
bbs4Bardet-Biedl syndrome 4. (604 aa)
ENSAMXP00000032034Uncharacterized protein. (1292 aa)
FOXC1Forkhead box C1. (541 aa)
LOC103035022Growth differentiation factor 6a. (406 aa)
mfrpMembrane frizzled-related protein. (594 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
rtn4ip1Reticulon 4 interacting protein 1. (402 aa)
get1Guided entry of tail-anchored proteins factor 1. (204 aa)
LOC103047576MARCKS-like 1b. (215 aa)
pfdn5Prefoldin 5. (153 aa)
LOC103040507Retinal homeobox gene 2. (330 aa)
ranGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (215 aa)
Tatdn1TatD DNase domain containing 1. (332 aa)
ENSAMXP00000052939Mediator complex subunit 27. (169 aa)
dcxUncharacterized protein. (691 aa)
LOC103039523Immunoglobulin like and fibronectin type III domain containing 1, tandem duplicate 1. (1466 aa)
LOC103036258Uncharacterized protein. (1475 aa)
ndpNorrin cystine knot growth factor NDP. (138 aa)
ENSAMXP00000050505Immunoglobulin like and fibronectin type III domain containing 1, tandem duplicate 4. (1175 aa)
igf2bp1Insulin-like growth factor 2 mRNA binding protein 1. (597 aa)
LOC103041475Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
ENSAMXP00000032674Uncharacterized protein. (2002 aa)
gpm6aGlycoprotein M6Aa. (281 aa)
LOC103038485Zinc finger protein 513b. (549 aa)
ENSAMXP00000033445Sidekick cell adhesion molecule 2b. (2034 aa)
tbx2T-box transcription factor 2b. (692 aa)
Impg2Interphotoreceptor matrix proteoglycan 2a. (259 aa)
nagluN-acetylglucosaminidase, alpha. (751 aa)
mpp5Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family. (658 aa)
Fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (523 aa)
ENSAMXP00000035888V-set and transmembrane domain containing 4a. (156 aa)
cln8CLN8 transmembrane ER and ERGIC protein. (288 aa)
ThrbThyroid hormone receptor beta. (490 aa)
Mib1Mindbomb E3 ubiquitin protein ligase 1. (1027 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
Nphp4Nephronophthisis 4. (293 aa)
ENSAMXP00000038761Basic helix-loop-helix family, member e23. (216 aa)
LOC103030186Zinc finger protein 513a. (557 aa)
LOC103025417Diencephalon/mesencephalon homeobox 1a. (383 aa)
LOC103032969Retinal homeobox gene 1. (334 aa)
LOC103025442LIM homeobox 1a. (405 aa)
tspan12Tetraspanin. (307 aa)
ENSAMXP00000044267Forkhead box Q2. (200 aa)
OTX2-2Orthodenticle homeobox 2. (298 aa)
LOC103040252Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (411 aa)
LOC103043365Peripherin 2-like b. (359 aa)
RING1Ring finger protein 1. (377 aa)
ift46Intraflagellar transport 46 homolog (Chlamydomonas). (356 aa)
LOC103030680Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. (898 aa)
ENSAMXP00000047014Uncharacterized protein. (270 aa)
ENSAMXP00000047395Uncharacterized protein. (327 aa)
prph2Peripherin 2a (retinal degeneration, slow). (345 aa)
usp45Ubiquitin carboxyl-terminal hydrolase. (804 aa)
W5JY90_ASTMXPhosphodiesterase. (817 aa)
W5JYT6_ASTMXAbelson helper integration site 1. (898 aa)
W5JZ29_ASTMXS-phase cyclin A-associated protein in the ER. (1312 aa)
lrp6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1618 aa)
LOC103026996Laminin, beta 1a. (1785 aa)
W5JZX3_ASTMXRp1 like 1a. (2457 aa)
W5K0Z5_ASTMXPaired box 6b. (417 aa)
bvesBlood vessel epicardial substance. (359 aa)
nrf1Nuclear respiratory factor 1. (503 aa)
Rs1F5/8 type C domain-containing protein. (310 aa)
Fat3FAT atypical cadherin 3a. (4535 aa)
W5K317_ASTMXUncharacterized protein. (678 aa)
hps1HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (672 aa)
LOC103042959Activated leukocyte cell adhesion molecule b. (564 aa)
LOC103041897V-set and transmembrane domain containing 4b. (317 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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