(27 nodes) Definitive hemopoiesis network (Astyanax mexicanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103025754	Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family. (157 aa)
	LOC103030342	Sp3b transcription factor. (658 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	LOC103047713	BHLH domain-containing protein. (422 aa)
	LOC103036248	IQ motif containing G. (375 aa)
	kri1	KRI1 homolog. (793 aa)
	ENSAMXP00000050817	Small ubiquitin like modifier 3a. (131 aa)
	ENSAMXP00000051191	Uncharacterized protein. (373 aa)
	LOC103040575	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	W5KC33_ASTMX	Ubiquitin-like domain-containing protein. (84 aa)
	hoxd4	Homeobox D4a. (256 aa)
	LOC103032373	Meis homeobox 2b. (381 aa)
	sp3	Sp3a transcription factor. (710 aa)
	Adar	Adenosine deaminase RNA specific. (1368 aa)
	Tal1	T-cell acute lymphocytic leukemia 1. (371 aa)
	ENSAMXP00000035277	SUMO1 activating enzyme subunit 1. (220 aa)
	Mib1	Mindbomb E3 ubiquitin protein ligase 1. (1027 aa)
	cdk5rap3	CDK5 regulatory subunit associated protein 3. (505 aa)
	LOC103045390	Small ubiquitin-related modifier. (95 aa)
	ENSAMXP00000042683	Uncharacterized protein. (72 aa)
	naca	Nascent polypeptide associated complex subunit alpha. (1026 aa)
	LOC103029138	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	gar1	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (230 aa)
	ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46. (1051 aa)
	Gpr183	G protein-coupled receptor 183a; Belongs to the G-protein coupled receptor 1 family. (370 aa)
	LOC103039499	Uncharacterized protein. (686 aa)
	cbfb	Core-binding factor subunit beta. (187 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000035277	ENSAMXP00000050817	ENSAMXP00000035277	ENSAMXP00000050817	SUMO1 activating enzyme subunit 1.	Small ubiquitin like modifier 3a.	0.883
ENSAMXP00000035277	LOC103025754	ENSAMXP00000035277	ENSAMXP00000045775	SUMO1 activating enzyme subunit 1.	Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.	0.872
ENSAMXP00000035277	LOC103029138	ENSAMXP00000035277	ENSAMXP00000045643	SUMO1 activating enzyme subunit 1.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.872
ENSAMXP00000035277	LOC103040575	ENSAMXP00000035277	ENSAMXP00000052145	SUMO1 activating enzyme subunit 1.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.872
ENSAMXP00000035277	LOC103045390	ENSAMXP00000035277	ENSAMXP00000042288	SUMO1 activating enzyme subunit 1.	Small ubiquitin-related modifier.	0.883
ENSAMXP00000035277	W5KC33_ASTMX	ENSAMXP00000035277	ENSAMXP00000005144	SUMO1 activating enzyme subunit 1.	Ubiquitin-like domain-containing protein.	0.976
ENSAMXP00000035277	sumo2	ENSAMXP00000035277	ENSAMXP00000019987	SUMO1 activating enzyme subunit 1.	Small ubiquitin-related modifier.	0.883
ENSAMXP00000042683	ENSAMXP00000050817	ENSAMXP00000042683	ENSAMXP00000050817	Uncharacterized protein.	Small ubiquitin like modifier 3a.	0.883
ENSAMXP00000042683	LOC103025754	ENSAMXP00000042683	ENSAMXP00000045775	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.	0.872
ENSAMXP00000042683	LOC103029138	ENSAMXP00000042683	ENSAMXP00000045643	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.872
ENSAMXP00000042683	LOC103040575	ENSAMXP00000042683	ENSAMXP00000052145	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.872
ENSAMXP00000042683	LOC103045390	ENSAMXP00000042683	ENSAMXP00000042288	Uncharacterized protein.	Small ubiquitin-related modifier.	0.883
ENSAMXP00000042683	W5KC33_ASTMX	ENSAMXP00000042683	ENSAMXP00000005144	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.976
ENSAMXP00000042683	sumo2	ENSAMXP00000042683	ENSAMXP00000019987	Uncharacterized protein.	Small ubiquitin-related modifier.	0.883
ENSAMXP00000050817	ENSAMXP00000035277	ENSAMXP00000050817	ENSAMXP00000035277	Small ubiquitin like modifier 3a.	SUMO1 activating enzyme subunit 1.	0.883
ENSAMXP00000050817	ENSAMXP00000042683	ENSAMXP00000050817	ENSAMXP00000042683	Small ubiquitin like modifier 3a.	Uncharacterized protein.	0.883
ENSAMXP00000050817	LOC103025754	ENSAMXP00000050817	ENSAMXP00000045775	Small ubiquitin like modifier 3a.	Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.	0.985
ENSAMXP00000050817	LOC103029138	ENSAMXP00000050817	ENSAMXP00000045643	Small ubiquitin like modifier 3a.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.985
ENSAMXP00000050817	LOC103040575	ENSAMXP00000050817	ENSAMXP00000052145	Small ubiquitin like modifier 3a.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.985
ENSAMXP00000050817	LOC103045390	ENSAMXP00000050817	ENSAMXP00000042288	Small ubiquitin like modifier 3a.	Small ubiquitin-related modifier.	0.901