STRINGSTRING
W5K0L4_ASTMX W5K0L4_ASTMX LOC103033117 LOC103033117 hps1 hps1 tgfb1 tgfb1 Smchd1 Smchd1 axin1 axin1 HESX1 HESX1 W5KA92_ASTMX W5KA92_ASTMX loxl3 loxl3 W5KF46_ASTMX W5KF46_ASTMX ctsz ctsz LOC103040345 LOC103040345 ccn2 ccn2 LOC103044365 LOC103044365 LOC103024607 LOC103024607 W5KU03_ASTMX W5KU03_ASTMX W5KUR6_ASTMX W5KUR6_ASTMX W5KUW3_ASTMX W5KUW3_ASTMX Bag6 Bag6 W5KY31_ASTMX W5KY31_ASTMX LOC103030717 LOC103030717 ep300 ep300 Adamtsl2 Adamtsl2 sp3 sp3 LOC103032002 LOC103032002 Dag1 Dag1 LOC103029625 LOC103029625 LOC103026238 LOC103026238 elk1 elk1 W5LDM9_ASTMX W5LDM9_ASTMX rpgrip1l rpgrip1l LOC103025751 LOC103025751 W5LM31_ASTMX W5LM31_ASTMX tgfbr2 tgfbr2 W5LN16_ASTMX W5LN16_ASTMX aimp2 aimp2 stk40 stk40 rbbp9 rbbp9 SRF SRF Bmpr2 Bmpr2 Eda Eda LOC103042872 LOC103042872 PTK7 PTK7 Wnt2b Wnt2b LOC103027348 LOC103027348 ctsh ctsh errfi1 errfi1 LOC103046407 LOC103046407 sav1 sav1 ENSAMXP00000037899 ENSAMXP00000037899 msc msc fgf2 fgf2 hhip hhip hspb11 hspb11 fgf7 fgf7 zfpm2 zfpm2 LOC103042847 LOC103042847 ENSAMXP00000041588 ENSAMXP00000041588 ENSAMXP00000041681 ENSAMXP00000041681 Wdpcp Wdpcp ENSAMXP00000042051 ENSAMXP00000042051 ENSAMXP00000042056 ENSAMXP00000042056 LOC103038145 LOC103038145 ENSAMXP00000042872 ENSAMXP00000042872 timeless timeless LOC103038135 LOC103038135 LOC103042559 LOC103042559 ENSAMXP00000043951 ENSAMXP00000043951 LOC103029147 LOC103029147 lef1 lef1 atxn1l atxn1l LOC103030342 LOC103030342 slc7a11 slc7a11 dlx3 dlx3 spry1 spry1 LOC103029481 LOC103029481 LOC103033610 LOC103033610 phex phex rspo2 rspo2 LOC103025891 LOC103025891 LOC103046764 LOC103046764 LOC103041475 LOC103041475 ENSAMXP00000050201 ENSAMXP00000050201 phox2b phox2b pkdcc pkdcc phf14 phf14 LOC103037384 LOC103037384 Dlg5 Dlg5 Numa1 Numa1 LOC103031663 LOC103031663 LOC103043058 LOC103043058 LOC103040573 LOC103040573
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5K0L4_ASTMXMADS-box domain-containing protein. (479 aa)
LOC103033117Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (302 aa)
hps1HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (672 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Smchd1Structural maintenance of chromosomes flexible hinge domain containing 1. (1960 aa)
axin1Axin 1. (866 aa)
HESX1HESX homeobox 1. (151 aa)
W5KA92_ASTMXDiscs, large homolog 5b (Drosophila), tandem duplicate 1; Belongs to the MAGUK family. (1806 aa)
loxl3Lysyl oxidase-like 3a. (733 aa)
W5KF46_ASTMXTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (561 aa)
ctszCathepsin Z; Belongs to the peptidase C1 family. (302 aa)
LOC103040345Ring finger and CCCH-type domains 2. (1061 aa)
ccn2Cellular communication network factor 2a. (362 aa)
LOC103044365E1A binding protein p300 a. (2671 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
W5KU03_ASTMXPept_C1 domain-containing protein; Belongs to the peptidase C1 family. (288 aa)
W5KUR6_ASTMXPolycystic kidney disease 1a. (4355 aa)
W5KUW3_ASTMXSi:dkey-91i10.2. (1125 aa)
Bag6BCL2 associated athanogene 6, like. (1193 aa)
W5KY31_ASTMXUncharacterized protein. (154 aa)
LOC103030717Uncharacterized protein. (750 aa)
ep300E1A binding protein p300 b. (2652 aa)
Adamtsl2ADAMTS-like 2. (923 aa)
sp3Sp3a transcription factor. (710 aa)
LOC103032002Integrin, alpha 3a; Belongs to the integrin alpha chain family. (995 aa)
Dag1Dystroglycan 1. (874 aa)
LOC103029625Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
LOC103026238Zinc finger protein, FOG family member 2b. (1118 aa)
elk1ETS transcription factor ELK1. (528 aa)
W5LDM9_ASTMXTGF-beta activated kinase 1/MAP3K7 binding protein 1. (537 aa)
rpgrip1lRPGRIP1 like. (1277 aa)
LOC103025751BCL2 associated athanogene 6. (1241 aa)
W5LM31_ASTMXSi:ch211-219a15.4. (1114 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
W5LN16_ASTMXHYDIN axonemal central pair apparatus protein. (4424 aa)
aimp2Aminoacyl tRNA synthetase complex interacting multifunctional protein 2. (316 aa)
stk40Serine/threonine kinase 40. (436 aa)
rbbp9Retinoblastoma binding protein 9. (184 aa)
SRFSerum response factor. (527 aa)
Bmpr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
EdaEctodysplasin A; Belongs to the tumor necrosis factor family. (449 aa)
LOC103042872Insulin-like growth factor binding protein 5a. (270 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1061 aa)
Wnt2bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (558 aa)
LOC103027348Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (146 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (333 aa)
errfi1ERBB receptor feedback inhibitor 1a. (480 aa)
LOC103046407Protein kinase domain containing, cytoplasmic b. (464 aa)
sav1Salvador family WW domain containing protein 1. (405 aa)
ENSAMXP00000037899MADS-box domain-containing protein. (356 aa)
mscMusculin (activated B-cell factor-1). (152 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
hhipHedgehog interacting protein. (693 aa)
hspb11Zgc:158640. (171 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (199 aa)
zfpm2Zinc finger protein, FOG family member 2a. (1151 aa)
LOC103042847Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b. (170 aa)
ENSAMXP00000041588Protein kinase domain-containing protein. (117 aa)
ENSAMXP00000041681Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (273 aa)
WdpcpUncharacterized protein. (98 aa)
ENSAMXP00000042051Integrin beta; Belongs to the integrin beta chain family. (503 aa)
ENSAMXP00000042056Chitin synthase 1. (1402 aa)
LOC103038145TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (362 aa)
ENSAMXP00000042872Uncharacterized protein. (98 aa)
timelessTimeless circadian clock. (1256 aa)
LOC103038135Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (169 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
ENSAMXP00000043951Integrin beta. (210 aa)
LOC103029147Distal-less homeobox 4b. (231 aa)
lef1Lymphoid enhancer-binding factor 1. (384 aa)
atxn1lAtaxin 1-like. (870 aa)
LOC103030342Sp3b transcription factor. (658 aa)
slc7a11Solute carrier family 7 member 11. (488 aa)
dlx3Distal-less homeobox 3b. (265 aa)
spry1Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (359 aa)
LOC103029481Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (208 aa)
LOC103033610Si:ch211-267e7.3. (968 aa)
phexPhosphate regulating endopeptidase homolog, X-linked. (744 aa)
rspo2R-spondin 2. (244 aa)
LOC103025891Si:ch211-153f2.3. (113 aa)
LOC103046764Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC103041475Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
ENSAMXP00000050201Pept_C1 domain-containing protein. (228 aa)
phox2bPaired like homeobox 2Bb. (284 aa)
pkdccProtein kinase domain containing, cytoplasmic a. (476 aa)
phf14PHD finger protein 14. (925 aa)
LOC103037384Uncharacterized protein. (170 aa)
Dlg5Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (1945 aa)
Numa1Uncharacterized protein. (2188 aa)
LOC103031663Transcription factor 21. (182 aa)
LOC103043058Lysyl oxidase-like 3b. (796 aa)
LOC103040573Integrin, alpha 3b; Belongs to the integrin alpha chain family. (1040 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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