48 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pdgfd	Platelet derived growth factor d. (351 aa)
	Glra2	Glycine receptor, alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (438 aa)
	cpeb1	Cytoplasmic polyadenylation element binding protein 1b. (569 aa)
	LOC103041009	Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
	W5KHA8_ASTMX	Glycine receptor, alpha 4b; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (449 aa)
	W5KHG8_ASTMX	Regulatory associated protein of MTOR, complex 1. (1305 aa)
	castor2	Cytosolic arginine sensor for mTORC1 subunit 2. (329 aa)
	UBR1	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1738 aa)
	LOC103023117	Si:zfos-80g12.1. (441 aa)
	LOC103025504	SH3-domain binding protein 4. (958 aa)
	Dnmt1	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1478 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (629 aa)
	W5L1Y0_ASTMX	Uncharacterized protein. (613 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2518 aa)
	ubr2	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1753 aa)
	klhl22	Kelch-like family member 22. (639 aa)
	Lamtor3	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (134 aa)
	lars1	Leucyl-tRNA synthetase b; Belongs to the class-I aminoacyl-tRNA synthetase family. (1178 aa)
	rragc	Ras-related GTP binding Ca. (382 aa)
	LOC103036251	Sestrin 2. (448 aa)
	LOC103024023	BAI1 associated protein 2. (528 aa)
	socs1	Suppressor of cytokine signaling 1a. (194 aa)
	amigo3	Adhesion molecule with Ig-like domain 3. (457 aa)
	amigo1	Adhesion molecule with Ig-like domain 1. (495 aa)
	lamtor4	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (99 aa)
	ENSAMXP00000028454	Cytoplasmic polyadenylation element binding protein 3. (597 aa)
	lamtor2	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
	lamtor5	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (94 aa)
	ENSAMXP00000029605	Uncharacterized protein. (62 aa)
	Xbp1	X-box binding protein 1. (264 aa)
	pdgfc	Platelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (341 aa)
	LOC103045388	Cytoplasmic polyadenylation element binding protein 1a. (558 aa)
	lamtor1	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (160 aa)
	slc38a9	Solute carrier family 38 member 9. (553 aa)
	LOC103037932	DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1347 aa)
	sesn1	Sestrin 1. (538 aa)
	CASTOR1	Cytosolic arginine sensor for mTORC1 subunit 1. (331 aa)
	LOC103035866	DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1514 aa)
	ipo5	Karyopherin (importin) beta 3. (1094 aa)
	LOC103023840	Cytoplasmic polyadenylation element binding protein 4a. (742 aa)
	LOC103027763	BAI1-associated protein 2a. (572 aa)
	ENSAMXP00000041752	Ras-related GTP binding D. (266 aa)
	Glra3	Glycine receptor, alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (492 aa)
	ENSAMXP00000042655	Ig-like domain-containing protein. (492 aa)
	LOC103043211	Ras-related GTP binding A. (315 aa)
	glra1	Glycine receptor, alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (460 aa)
	LOC103032417	SH3-domain binding protein 4a. (972 aa)
	gclm	Glutamate-cysteine ligase, modifier subunit. (271 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASTOR1	ENSAMXP00000041752	ENSAMXP00000035086	ENSAMXP00000041752	Cytosolic arginine sensor for mTORC1 subunit 1.	Ras-related GTP binding D.	0.419
CASTOR1	LOC103043211	ENSAMXP00000035086	ENSAMXP00000043157	Cytosolic arginine sensor for mTORC1 subunit 1.	Ras-related GTP binding A.	0.480
CASTOR1	Lamtor3	ENSAMXP00000035086	ENSAMXP00000018108	Cytosolic arginine sensor for mTORC1 subunit 1.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.	0.515
CASTOR1	W5KHG8_ASTMX	ENSAMXP00000035086	ENSAMXP00000007030	Cytosolic arginine sensor for mTORC1 subunit 1.	Regulatory associated protein of MTOR, complex 1.	0.466
CASTOR1	castor2	ENSAMXP00000035086	ENSAMXP00000007707	Cytosolic arginine sensor for mTORC1 subunit 1.	Cytosolic arginine sensor for mTORC1 subunit 2.	0.901
CASTOR1	lamtor1	ENSAMXP00000035086	ENSAMXP00000032534	Cytosolic arginine sensor for mTORC1 subunit 1.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	0.535
CASTOR1	lamtor2	ENSAMXP00000035086	ENSAMXP00000052294	Cytosolic arginine sensor for mTORC1 subunit 1.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	0.536
CASTOR1	lamtor4	ENSAMXP00000035086	ENSAMXP00000027581	Cytosolic arginine sensor for mTORC1 subunit 1.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	0.448
CASTOR1	lamtor5	ENSAMXP00000035086	ENSAMXP00000029211	Cytosolic arginine sensor for mTORC1 subunit 1.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5.	0.539
CASTOR1	rragc	ENSAMXP00000035086	ENSAMXP00000020918	Cytosolic arginine sensor for mTORC1 subunit 1.	Ras-related GTP binding Ca.	0.419
Dnmt1	LOC103035866	ENSAMXP00000012561	ENSAMXP00000035622	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.899
Dnmt1	LOC103037932	ENSAMXP00000012561	ENSAMXP00000033648	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.846
ENSAMXP00000029605	gclm	ENSAMXP00000029605	ENSAMXP00000049121	Uncharacterized protein.	Glutamate-cysteine ligase, modifier subunit.	0.966
ENSAMXP00000041752	CASTOR1	ENSAMXP00000041752	ENSAMXP00000035086	Ras-related GTP binding D.	Cytosolic arginine sensor for mTORC1 subunit 1.	0.419
ENSAMXP00000041752	LOC103023117	ENSAMXP00000041752	ENSAMXP00000008566	Ras-related GTP binding D.	Si:zfos-80g12.1.	0.506
ENSAMXP00000041752	LOC103025504	ENSAMXP00000041752	ENSAMXP00000010701	Ras-related GTP binding D.	SH3-domain binding protein 4.	0.425
ENSAMXP00000041752	LOC103032417	ENSAMXP00000041752	ENSAMXP00000043765	Ras-related GTP binding D.	SH3-domain binding protein 4a.	0.425
ENSAMXP00000041752	LOC103036251	ENSAMXP00000041752	ENSAMXP00000021231	Ras-related GTP binding D.	Sestrin 2.	0.517
ENSAMXP00000041752	LOC103043211	ENSAMXP00000041752	ENSAMXP00000043157	Ras-related GTP binding D.	Ras-related GTP binding A.	0.997
ENSAMXP00000041752	Lamtor3	ENSAMXP00000041752	ENSAMXP00000018108	Ras-related GTP binding D.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.	0.992