(21 nodes) Positive regulation of release of cytochrome c from mitochondria network (Astyanax mexicanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Pla2g6	Phospholipase A2, group VI (cytosolic, calcium-independent). (822 aa)
	Bax	BCL2 associated X, apoptosis regulator a. (190 aa)
	LOC103047816	Zgc:153993. (204 aa)
	W5L5Z2_ASTMX	Family with sequence similarity 162 member A. (216 aa)
	mllt11	MLLT11 transcription factor 7 cofactor. (86 aa)
	ENSAMXP00000027247	Uncharacterized protein. (197 aa)
	ENSAMXP00000027415	Uncharacterized protein. (195 aa)
	bnip3	BCL2 interacting protein 3. (198 aa)
	LOC103032659	BCL2 associated agonist of cell death b. (179 aa)
	ENSAMXP00000033078	Uncharacterized protein. (214 aa)
	LOC103028006	Uncharacterized protein. (212 aa)
	ENSAMXP00000034759	Neuromast-expressed gpi-anchored lymphocyte antigen 6. (278 aa)
	ENSAMXP00000036374	UPAR/Ly6 domain-containing protein. (196 aa)
	LOC103042396	Uncharacterized protein. (181 aa)
	pink1	PTEN induced kinase 1. (571 aa)
	LOC111196769	Uncharacterized protein. (215 aa)
	bcl2l11	Bclx_interact domain-containing protein. (203 aa)
	bmf	Uncharacterized protein. (155 aa)
	ENSAMXP00000051857	Uncharacterized protein. (242 aa)
	pdcd5	Programmed cell death 5. (135 aa)
	ENSAMXP00000054934	Uncharacterized protein. (242 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bax	ENSAMXP00000027415	ENSAMXP00000005311	ENSAMXP00000027415	BCL2 associated X, apoptosis regulator a.	Uncharacterized protein.	0.450
Bax	LOC103032659	ENSAMXP00000005311	ENSAMXP00000029182	BCL2 associated X, apoptosis regulator a.	BCL2 associated agonist of cell death b.	0.774
Bax	LOC103047816	ENSAMXP00000005311	ENSAMXP00000007605	BCL2 associated X, apoptosis regulator a.	Zgc:153993.	0.904
Bax	bcl2l11	ENSAMXP00000005311	ENSAMXP00000046456	BCL2 associated X, apoptosis regulator a.	Bclx_interact domain-containing protein.	0.991
Bax	bmf	ENSAMXP00000005311	ENSAMXP00000048662	BCL2 associated X, apoptosis regulator a.	Uncharacterized protein.	0.450
ENSAMXP00000027415	Bax	ENSAMXP00000027415	ENSAMXP00000005311	Uncharacterized protein.	BCL2 associated X, apoptosis regulator a.	0.450
ENSAMXP00000027415	LOC103042396	ENSAMXP00000027415	ENSAMXP00000040866	Uncharacterized protein.	Uncharacterized protein.	0.450
ENSAMXP00000027415	LOC103047816	ENSAMXP00000027415	ENSAMXP00000007605	Uncharacterized protein.	Zgc:153993.	0.545
ENSAMXP00000027415	bcl2l11	ENSAMXP00000027415	ENSAMXP00000046456	Uncharacterized protein.	Bclx_interact domain-containing protein.	0.443
LOC103032659	Bax	ENSAMXP00000029182	ENSAMXP00000005311	BCL2 associated agonist of cell death b.	BCL2 associated X, apoptosis regulator a.	0.774
LOC103032659	LOC103042396	ENSAMXP00000029182	ENSAMXP00000040866	BCL2 associated agonist of cell death b.	Uncharacterized protein.	0.784
LOC103032659	LOC103047816	ENSAMXP00000029182	ENSAMXP00000007605	BCL2 associated agonist of cell death b.	Zgc:153993.	0.827
LOC103032659	bcl2l11	ENSAMXP00000029182	ENSAMXP00000046456	BCL2 associated agonist of cell death b.	Bclx_interact domain-containing protein.	0.743
LOC103042396	ENSAMXP00000027415	ENSAMXP00000040866	ENSAMXP00000027415	Uncharacterized protein.	Uncharacterized protein.	0.450
LOC103042396	LOC103032659	ENSAMXP00000040866	ENSAMXP00000029182	Uncharacterized protein.	BCL2 associated agonist of cell death b.	0.784
LOC103042396	LOC103047816	ENSAMXP00000040866	ENSAMXP00000007605	Uncharacterized protein.	Zgc:153993.	0.810
LOC103042396	bcl2l11	ENSAMXP00000040866	ENSAMXP00000046456	Uncharacterized protein.	Bclx_interact domain-containing protein.	0.994
LOC103042396	bmf	ENSAMXP00000040866	ENSAMXP00000048662	Uncharacterized protein.	Uncharacterized protein.	0.450
LOC103047816	Bax	ENSAMXP00000007605	ENSAMXP00000005311	Zgc:153993.	BCL2 associated X, apoptosis regulator a.	0.904
LOC103047816	ENSAMXP00000027415	ENSAMXP00000007605	ENSAMXP00000027415	Zgc:153993.	Uncharacterized protein.	0.545