44 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W5LBA0_ASTMX	Neuroligin 1. (586 aa)
	lrrtm1	Leucine rich repeat transmembrane neuronal 1. (524 aa)
	lrrtm2	Leucine rich repeat transmembrane neuronal 2. (543 aa)
	SLITRK1	SLIT and NTRK like family member 1. (690 aa)
	LOC103038528	Neuropilin (NRP) and tolloid (TLL)-like 1. (531 aa)
	LOC103025423	Shisa family member 7. (643 aa)
	LOC103022039	Leucine rich repeat and fibronectin type III domain containing 4a. (879 aa)
	ENSAMXP00000029236	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (275 aa)
	LOC103028306	Leucine rich repeat and fibronectin type III domain containing 5a. (786 aa)
	LOC103022054	Neuroligin 4 X-linked b. (813 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (903 aa)
	ENSAMXP00000031537	Leucine rich repeat and fibronectin type III domain containing 4b. (891 aa)
	LOC103042184	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (335 aa)
	ENSAMXP00000035901	COesterase domain-containing protein. (188 aa)
	LOC103033058	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (455 aa)
	ENSAMXP00000036425	Si:ch211-276c2.2. (882 aa)
	cacng4	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (322 aa)
	ENSAMXP00000038286	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (299 aa)
	LRFN2	Leucine rich repeat and fibronectin type III domain containing 2. (780 aa)
	LOC103030391	Gamma-aminobutyric acid type A receptor alpha2 subunit a; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
	nptn	Neuroplastin b. (398 aa)
	clstn2	Calsyntenin 2. (945 aa)
	LOC103047251	Calcium channel, voltage-dependent, gamma subunit 3b. (309 aa)
	LOC103021510	Neuroplastin a. (404 aa)
	LOC103022482	Neuroligin 4 X-linked a. (853 aa)
	ENSAMXP00000045779	Neuroligin 2b. (905 aa)
	neto1	Neuropilin (NRP) and tolloid (TLL)-like 1, like. (540 aa)
	LOC103039925	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (335 aa)
	LOC103029737	Leucine rich repeat and fibronectin type III domain containing 5b. (800 aa)
	LOC103030680	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. (898 aa)
	LOC103029856	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (324 aa)
	Shisa6	Uncharacterized protein. (138 aa)
	ENSAMXP00000050086	Uncharacterized protein. (328 aa)
	ENSAMXP00000050631	Uncharacterized protein. (189 aa)
	GRIN3A	Glutamate ionotropic receptor NMDA type subunit 3A. (1144 aa)
	ENSAMXP00000052634	Uncharacterized protein. (437 aa)
	W5JZK3_ASTMX	Si:ch73-330k17.3. (229 aa)
	nlgn2	Neuroligin 2a. (829 aa)
	W5KP74_ASTMX	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
	LOC103024250	Leucine rich repeat and fibronectin type III domain containing 2b. (797 aa)
	LOC103039500	Leucine rich repeat and fibronectin type III domain containing 1. (780 aa)
	clstn1	Calsyntenin 1. (971 aa)
	Nlgn3	Neuroligin 3a. (844 aa)
	W5L9N9_ASTMX	Shisa family member 7a. (370 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2	LOC103030680	ENSAMXP00000031306	ENSAMXP00000046775	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins.	0.901
ENSAMXP00000031537	ENSAMXP00000052634	ENSAMXP00000031537	ENSAMXP00000052634	Leucine rich repeat and fibronectin type III domain containing 4b.	Uncharacterized protein.	0.443
ENSAMXP00000035901	W5LBA0_ASTMX	ENSAMXP00000035901	ENSAMXP00000017112	COesterase domain-containing protein.	Neuroligin 1.	0.750
ENSAMXP00000050086	Shisa6	ENSAMXP00000050086	ENSAMXP00000048586	Uncharacterized protein.	Uncharacterized protein.	0.773
ENSAMXP00000050631	LOC103039500	ENSAMXP00000050631	ENSAMXP00000012139	Uncharacterized protein.	Leucine rich repeat and fibronectin type III domain containing 1.	0.439
ENSAMXP00000052634	ENSAMXP00000031537	ENSAMXP00000052634	ENSAMXP00000031537	Uncharacterized protein.	Leucine rich repeat and fibronectin type III domain containing 4b.	0.443
ENSAMXP00000052634	LOC103022039	ENSAMXP00000052634	ENSAMXP00000029088	Uncharacterized protein.	Leucine rich repeat and fibronectin type III domain containing 4a.	0.443
ENSAMXP00000052634	SLITRK1	ENSAMXP00000052634	ENSAMXP00000026451	Uncharacterized protein.	SLIT and NTRK like family member 1.	0.408
LOC103022039	ENSAMXP00000052634	ENSAMXP00000029088	ENSAMXP00000052634	Leucine rich repeat and fibronectin type III domain containing 4a.	Uncharacterized protein.	0.443
LOC103024250	LOC103039500	ENSAMXP00000009457	ENSAMXP00000012139	Leucine rich repeat and fibronectin type III domain containing 2b.	Leucine rich repeat and fibronectin type III domain containing 1.	0.448
LOC103029856	cacng4	ENSAMXP00000047740	ENSAMXP00000036843	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.443
LOC103030680	CDH2	ENSAMXP00000046775	ENSAMXP00000031306	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.901
LOC103039500	ENSAMXP00000050631	ENSAMXP00000012139	ENSAMXP00000050631	Leucine rich repeat and fibronectin type III domain containing 1.	Uncharacterized protein.	0.439
LOC103039500	LOC103024250	ENSAMXP00000012139	ENSAMXP00000009457	Leucine rich repeat and fibronectin type III domain containing 1.	Leucine rich repeat and fibronectin type III domain containing 2b.	0.448
LOC103039500	LRFN2	ENSAMXP00000012139	ENSAMXP00000040239	Leucine rich repeat and fibronectin type III domain containing 1.	Leucine rich repeat and fibronectin type III domain containing 2.	0.451
LOC103039925	cacng4	ENSAMXP00000046025	ENSAMXP00000036843	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.443
LOC103042184	cacng4	ENSAMXP00000034957	ENSAMXP00000036843	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.441
LRFN2	LOC103039500	ENSAMXP00000040239	ENSAMXP00000012139	Leucine rich repeat and fibronectin type III domain containing 2.	Leucine rich repeat and fibronectin type III domain containing 1.	0.451
SLITRK1	ENSAMXP00000052634	ENSAMXP00000026451	ENSAMXP00000052634	SLIT and NTRK like family member 1.	Uncharacterized protein.	0.408
Shisa6	ENSAMXP00000050086	ENSAMXP00000048586	ENSAMXP00000050086	Uncharacterized protein.	Uncharacterized protein.	0.773