19 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103032217	Dickkopf_N domain-containing protein. (277 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	LOC103024607	Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
	ar	Androgen receptor. (839 aa)
	W5L1C8_ASTMX	Uncharacterized protein. (350 aa)
	LOC103029625	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
	dkk1	Dickkopf WNT signaling pathway inhibitor 1b. (243 aa)
	Wnt2b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (558 aa)
	LOC103029324	Bone morphogenetic protein 16. (430 aa)
	stox1	Storkhead box 1. (986 aa)
	LOC103038582	Si:ch211-286o17.1. (326 aa)
	gdnf	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (245 aa)
	ENSAMXP00000045776	Nerve growth factor receptor a (TNFR superfamily, member 16). (419 aa)
	bmp4	TGF_BETA_2 domain-containing protein. (481 aa)
	spry1	Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (359 aa)
	LOC107197240	BHLH domain-containing protein. (244 aa)
	LOC103045744	Colony stimulating factor 1a (macrophage). (531 aa)
	ENSAMXP00000050565	Dickkopf WNT signaling pathway inhibitor 1a. (277 aa)
	ENSAMXP00000054825	Colony stimulating factor 1b (macrophage). (298 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000045776	LOC103045744	ENSAMXP00000045776	ENSAMXP00000049426	Nerve growth factor receptor a (TNFR superfamily, member 16).	Colony stimulating factor 1a (macrophage).	0.654
ENSAMXP00000045776	gdnf	ENSAMXP00000045776	ENSAMXP00000043291	Nerve growth factor receptor a (TNFR superfamily, member 16).	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	0.517
LOC103024607	tgfb1	ENSAMXP00000010023	ENSAMXP00000002667	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.902
LOC103045744	ENSAMXP00000045776	ENSAMXP00000049426	ENSAMXP00000045776	Colony stimulating factor 1a (macrophage).	Nerve growth factor receptor a (TNFR superfamily, member 16).	0.654
W5L1C8_ASTMX	ar	ENSAMXP00000013640	ENSAMXP00000011713	Uncharacterized protein.	Androgen receptor.	0.901
ar	W5L1C8_ASTMX	ENSAMXP00000011713	ENSAMXP00000013640	Androgen receptor.	Uncharacterized protein.	0.901
bmp4	dkk1	ENSAMXP00000046234	ENSAMXP00000018708	TGF_BETA_2 domain-containing protein.	Dickkopf WNT signaling pathway inhibitor 1b.	0.419
dkk1	bmp4	ENSAMXP00000018708	ENSAMXP00000046234	Dickkopf WNT signaling pathway inhibitor 1b.	TGF_BETA_2 domain-containing protein.	0.419
gdnf	ENSAMXP00000045776	ENSAMXP00000043291	ENSAMXP00000045776	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	Nerve growth factor receptor a (TNFR superfamily, member 16).	0.517
tgfb1	LOC103024607	ENSAMXP00000002667	ENSAMXP00000010023	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.902