88 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAMXP00000037569	Gla domain-containing protein. (157 aa)
	prkaa1	Non-specific serine/threonine protein kinase. (573 aa)
	LOC103041890	Aquaporin 1a (Colton blood group), tandem duplicate 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (266 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
	fosl1	FOS-like antigen 1a. (356 aa)
	LOC103042476	Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
	Ptrhd1	Peptidyl-tRNA hydrolase domain containing 1. (144 aa)
	LOC103035536	Periostin, osteoblast specific factor a. (947 aa)
	Adcy3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1141 aa)
	LOC103026363	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (421 aa)
	LOC103033011	Prostaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family. (463 aa)
	ENSAMXP00000046311	Si:dkey-23i12.7. (155 aa)
	Acod1	Aconitate decarboxylase 1. (521 aa)
	ENSAMXP00000045240	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (281 aa)
	ENSAMXP00000044990	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (259 aa)
	adcy5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1205 aa)
	ENSAMXP00000044610	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (313 aa)
	ENSAMXP00000044322	Uncharacterized protein. (353 aa)
	ENSAMXP00000044245	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (321 aa)
	ENSAMXP00000043754	Chemokine (C-C motif) ligand 19a, tandem duplicate 1. (117 aa)
	LOC103047163	BCL2 associated agonist of cell death a. (213 aa)
	Hsd3b7	Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase. (289 aa)
	dcps	Decapping enzyme, scavenger. (321 aa)
	gdf11	Growth differentiation factor 11. (409 aa)
	LOC103021521	Si:dkey-27b3.2. (293 aa)
	rwdd1	RWD domain containing 1. (240 aa)
	gas6	Uncharacterized protein. (659 aa)
	ENSAMXP00000040228	CARD domain-containing protein. (110 aa)
	LOC103035024	Uncharacterized protein. (1040 aa)
	LOC103023460	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	ENSAMXP00000038286	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (299 aa)
	cda	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (148 aa)
	nkx3-1	NK3 homeobox 1. (202 aa)
	errfi1	ERBB receptor feedback inhibitor 1a. (480 aa)
	ABHD2	Abhydrolase domain containing 2a. (415 aa)
	LOC103044943	Chemokine (C-C motif) ligand 19a, tandem duplicate 2. (126 aa)
	LOC103034748	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1092 aa)
	hsd3b1	Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (374 aa)
	hamp	Uncharacterized protein. (99 aa)
	LOC103042747	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1174 aa)
	ENSAMXP00000032866	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1148 aa)
	aifm1	Apoptosis inducing factor mitochondrion associated 1. (802 aa)
	LOC103025471	Prostaglandin E receptor 4 (subtype EP4) a; Belongs to the G-protein coupled receptor 1 family. (452 aa)
	LOC103036816	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (526 aa)
	Usp8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1053 aa)
	ENSAMXP00000029461	Cytidine deaminase b. (150 aa)
	ENSAMXP00000029236	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (275 aa)
	LOC103032659	BCL2 associated agonist of cell death b. (179 aa)
	LOC111190642	Gla domain-containing protein. (101 aa)
	LOC103035710	Prostaglandin E receptor 2a (subtype EP2); Belongs to the G-protein coupled receptor 1 family. (367 aa)
	ENSAMXP00000027521	Uncharacterized protein. (387 aa)
	LOC103035761	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a. (354 aa)
	P2RY6	Pyrimidinergic receptor P2Y6. (327 aa)
	W5LTC8_ASTMX	Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (523 aa)
	Fibin	Fin bud initiation factor a. (182 aa)
	LOC103038466	Si:dkey-6n21.13; Belongs to the G-protein coupled receptor 1 family. (421 aa)
	tbxa2r	Thromboxane A2 receptor. (375 aa)
	Xrn1	5'-3' exoribonuclease 1. (1650 aa)
	golph3	Golgi phosphoprotein 3. (290 aa)
	tfap4	Transcription factor AP-4 (activating enhancer binding protein 4). (330 aa)
	ptgfr	Prostaglandin F receptor (FP); Belongs to the G-protein coupled receptor 1 family. (373 aa)
	elk1	ETS transcription factor ELK1. (528 aa)
	tgfb3	Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
	W5L372_ASTMX	Immunoresponsive gene 1, like. (475 aa)
	W5L2G6_ASTMX	Abhydrolase domain containing 2b. (431 aa)
	prkaa2	Non-specific serine/threonine protein kinase. (560 aa)
	W5L1C8_ASTMX	Uncharacterized protein. (350 aa)
	pck1	Phosphoenolpyruvate carboxykinase 1 (soluble). (624 aa)
	ube3a	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (873 aa)
	NDOR1	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (618 aa)
	W5KXQ8_ASTMX	Periostin, osteoblast specific factor b. (771 aa)
	LOC103031589	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1183 aa)
	ar	Androgen receptor. (839 aa)
	W5KVD8_ASTMX	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (135 aa)
	W5KVD0_ASTMX	Si:dkey-19b23.10. (714 aa)
	tgfbi	Transforming growth factor, beta-induced. (677 aa)
	LOC103038005	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
	LOC103024607	Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
	adcy8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1228 aa)
	LOC103029411	Prostaglandin E receptor 2b (subtype EP2). (343 aa)
	recql5	RecQ helicase-like 5. (1031 aa)
	W5KP74_ASTMX	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
	LOC103030080	Prostaglandin E receptor 4 (subtype EP4) b. (464 aa)
	Pck2	Phosphoenolpyruvate carboxykinase 2 (mitochondrial). (618 aa)
	park7	Parkinson protein 7. (189 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	tat	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (487 aa)
	cftr	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1486 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Acod1	aifm1	ENSAMXP00000045503	ENSAMXP00000032353	Aconitate decarboxylase 1.	Apoptosis inducing factor mitochondrion associated 1.	0.691
Adcy3	ENSAMXP00000032866	ENSAMXP00000047264	ENSAMXP00000032866	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.445
Adcy3	ENSAMXP00000044322	ENSAMXP00000047264	ENSAMXP00000044322	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.418
Adcy3	LOC103031589	ENSAMXP00000047264	ENSAMXP00000012174	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.445
Adcy3	LOC103035761	ENSAMXP00000047264	ENSAMXP00000027516	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a.	0.787
Adcy3	adcy8	ENSAMXP00000047264	ENSAMXP00000009842	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.445
ENSAMXP00000029236	ENSAMXP00000032866	ENSAMXP00000029236	ENSAMXP00000032866	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.436
ENSAMXP00000029236	ENSAMXP00000044322	ENSAMXP00000029236	ENSAMXP00000044322	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Uncharacterized protein.	0.418
ENSAMXP00000029236	ENSAMXP00000045240	ENSAMXP00000029236	ENSAMXP00000045240	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.467
ENSAMXP00000029236	LOC103031589	ENSAMXP00000029236	ENSAMXP00000012174	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.432
ENSAMXP00000029236	LOC103034748	ENSAMXP00000029236	ENSAMXP00000033635	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.427
ENSAMXP00000029236	LOC103035761	ENSAMXP00000029236	ENSAMXP00000027516	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a.	0.418
ENSAMXP00000029236	adcy8	ENSAMXP00000029236	ENSAMXP00000009842	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.422
ENSAMXP00000029461	W5KVD8_ASTMX	ENSAMXP00000029461	ENSAMXP00000011550	Cytidine deaminase b.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.904
ENSAMXP00000029461	cda	ENSAMXP00000029461	ENSAMXP00000037727	Cytidine deaminase b.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.903
ENSAMXP00000032866	Adcy3	ENSAMXP00000032866	ENSAMXP00000047264	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.445
ENSAMXP00000032866	ENSAMXP00000029236	ENSAMXP00000032866	ENSAMXP00000029236	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.436
ENSAMXP00000032866	ENSAMXP00000038286	ENSAMXP00000032866	ENSAMXP00000038286	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.433
ENSAMXP00000032866	ENSAMXP00000044322	ENSAMXP00000032866	ENSAMXP00000044322	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.419
ENSAMXP00000032866	LOC103034748	ENSAMXP00000032866	ENSAMXP00000033635	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.464