148 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103022359	Mothers against decapentaplegic homolog. (587 aa)
	W5JY97_ASTMX	Tubulin folding cofactor D. (1103 aa)
	LOC103036047	Leiomodin 2 (cardiac) a. (510 aa)
	LOC103022480	LIM zinc-binding domain-containing protein. (1356 aa)
	W5K2D9_ASTMX	Uncharacterized protein. (56 aa)
	W5K3Q4_ASTMX	LIM zinc-binding domain-containing protein. (77 aa)
	vill	Villin-like. (866 aa)
	WDR63	WD repeat domain 63. (881 aa)
	plekhh2	Pleckstrin homology domain containing, family H (with MyTH4 domain) member 2. (1426 aa)
	arhgef2	Rho/rac guanine nucleotide exchange factor (GEF) 2. (1185 aa)
	W5KBN8_ASTMX	LIM domain and actin binding 1a. (703 aa)
	vil1	Villin 1. (842 aa)
	SPTBN1	Spectrin beta chain; Belongs to the spectrin family. (2110 aa)
	W5KH82_ASTMX	Scinderin like b. (704 aa)
	W5KHI7_ASTMX	Slingshot protein phosphatase 1b. (656 aa)
	LOC103023282	Twinfilin actin-binding protein 2b. (363 aa)
	W5KIL9_ASTMX	Clusterin; Belongs to the clusterin family. (407 aa)
	cryab	Crystallin, alpha B, b; Belongs to the small heat shock protein (HSP20) family. (172 aa)
	W5KJB0_ASTMX	Thymosin beta 2. (44 aa)
	tmsb10	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (42 aa)
	W5KLR5_ASTMX	PH domain-containing protein. (2145 aa)
	LOC103033421	Spectrin beta chain; Belongs to the spectrin family. (2358 aa)
	LOC103027267	Gelsolin b. (729 aa)
	LOC103043091	Elastin microfibril interfacer 1a. (1050 aa)
	W5KRV2_ASTMX	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (757 aa)
	flii	FLII actin remodeling protein. (1257 aa)
	scin	Scinderin. (725 aa)
	bmerb1	BMERB domain containing 1. (200 aa)
	rhpn1	Rhophilin, Rho GTPase binding protein 1. (664 aa)
	W5L261_ASTMX	Adducin 3 (gamma) a. (643 aa)
	LOC103025505	Calmodulin regulated spectrin-associated protein 1b. (1555 aa)
	atxn7	Ataxin 7. (879 aa)
	W5L5A1_ASTMX	Calmodulin regulated spectrin-associated protein 1a. (715 aa)
	LOC103047464	Twinfilin actin-binding protein 1a. (350 aa)
	W5L760_ASTMX	Supervillin c. (1348 aa)
	LOC103046347	Si:ch211-203d1.3. (642 aa)
	LOC103041876	Thyroglobulin type-1 domain-containing protein. (293 aa)
	LOC103039625	Scinderin like a. (740 aa)
	W5LD66_ASTMX	Mothers against decapentaplegic homolog. (573 aa)
	clu	Clusterin; Belongs to the clusterin family. (451 aa)
	W5LH61_ASTMX	Inositol polyphosphate-5-phosphatase Ja. (553 aa)
	apc2	APC regulator of WNT signaling pathway 2. (2532 aa)
	LOC103029394	Mothers against decapentaplegic homolog. (544 aa)
	LOC103031360	Slingshot protein phosphatase 2b. (1194 aa)
	Apc	APC regulator of WNT signaling pathway. (2701 aa)
	ssh1	Slingshot protein phosphatase 1a. (1007 aa)
	LOC103039081	FERM domain containing 7. (759 aa)
	rhpn2	Rhophilin, Rho GTPase binding protein 2. (687 aa)
	LOC103046517	Adducin 3 (gamma) b. (692 aa)
	W5LN37_ASTMX	SH3 and multiple ankyrin repeat domains 2a. (1756 aa)
	W5LQ08_ASTMX	Spectrin beta chain; Belongs to the spectrin family. (2443 aa)
	W5LQA2_ASTMX	P21 protein (Cdc42/Rac)-activated kinase 2b; Belongs to the protein kinase superfamily. (489 aa)
	avil	Advillin. (817 aa)
	lmod1	Leiomodin 1b (smooth muscle). (703 aa)
	W5LSA1_ASTMX	Uncharacterized protein. (283 aa)
	LOC103029577	MARVEL domain-containing protein. (304 aa)
	LOC103047303	Myeloid associated differentiation marker. (296 aa)
	LOC103040076	Si:dkeyp-66d1.7. (293 aa)
	PFDN2	Prefoldin subunit 2. (163 aa)
	ENSAMXP00000027412	HP domain-containing protein. (70 aa)
	Add1	Adducin 1 (alpha). (786 aa)
	ENSAMXP00000027852	Uncharacterized protein. (624 aa)
	ENSAMXP00000028141	Uncharacterized protein. (242 aa)
	ENSAMXP00000028486	Mothers against decapentaplegic homolog. (493 aa)
	ENSAMXP00000028508	Calponin-homology (CH) domain-containing protein. (99 aa)
	tmod4	Tropomodulin 4 (muscle). (391 aa)
	Gmfb	Glia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (138 aa)
	LOC103022806	KN motif and ankyrin repeat domains 1b. (1256 aa)
	LOC103042228	Chondroadherin-like b. (782 aa)
	ENSAMXP00000031175	Twinfilin actin-binding protein 1b. (335 aa)
	bbs4	Bardet-Biedl syndrome 4. (604 aa)
	LOC103043485	FERM domain-containing protein. (710 aa)
	ENSAMXP00000032701	PH domain-containing protein. (202 aa)
	LOC103046197	Supervillin d. (1479 aa)
	kank1	KN motif and ankyrin repeat domains 1. (1337 aa)
	ENSAMXP00000033147	HP domain-containing protein. (81 aa)
	pfdn2	Prefoldin subunit 2. (154 aa)
	ENSAMXP00000034004	CKK domain-containing protein. (171 aa)
	LOC103040991	Stathmin; Belongs to the stathmin family. (180 aa)
	spef1	Zgc:66426. (238 aa)
	f11r	F11 receptor, tandem duplicate 1. (301 aa)
	GMFG	ADF-H domain-containing protein. (228 aa)
	ENSAMXP00000035054	Uncharacterized protein. (63 aa)
	camsap2	Calmodulin regulated spectrin-associated protein family, member 2a. (1429 aa)
	lmod3	Leiomodin 3 (fetal). (707 aa)
	ENSAMXP00000036236	Slingshot protein phosphatase 2a. (1158 aa)
	LOC103022587	Twinfilin actin-binding protein 2a. (352 aa)
	pfdn6	Prefoldin subunit 6. (126 aa)
	ENSAMXP00000037509	Uncharacterized protein. (189 aa)
	ENSAMXP00000037683	Ataxin 7-like 2a. (718 aa)
	LOC103038576	SH3 and multiple ankyrin repeat domains 3b. (1639 aa)
	ENSAMXP00000038337	Uncharacterized protein. (59 aa)
	vbp1	Von Hippel-Lindau binding protein 1. (208 aa)
	LOC103042463	Tropomodulin 2. (385 aa)
	LOC103040094	Calmodulin regulated spectrin-associated protein family, member 2b. (1463 aa)
	Olfm3	Olfactomedin 3a. (287 aa)
	LOC103035089	Leiomodin 1a (smooth muscle). (751 aa)
	ENSAMXP00000040470	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa)
	LOC103033745	Gelsolin a. (738 aa)
	LOC103039722	Microtubule-associated protein, RP/EB family, member 1a. (256 aa)
	cib1	Calcium and integrin binding 1 (calmyrin). (190 aa)
	myoc	Myocilin. (483 aa)
	LOC103032213	Spectrin beta chain; Belongs to the spectrin family. (2388 aa)
	ENSAMXP00000042222	Heparan sulfate proteoglycan 2. (3490 aa)
	ENSAMXP00000042233	WH2 domain-containing protein. (146 aa)
	LOC103028505	PH domain-containing protein. (2305 aa)
	mapre1	Microtubule-associated protein, RP/EB family, member 1b. (274 aa)
	ENSAMXP00000043039	annotation not available (99 aa)
	ENSAMXP00000043075	Calponin-homology (CH) domain-containing protein. (1896 aa)
	LOC103029958	Epithelial cell adhesion molecule. (343 aa)
	ENSAMXP00000043896	Zgc:171844. (209 aa)
	ENSAMXP00000044163	CKK domain-containing protein. (166 aa)
	Map6d1	MAP6 domain containing 1. (286 aa)
	ENSAMXP00000044530	Elastin microfibril interfacer 1b. (992 aa)
	LOC103038738	Olfactomedin-like domain-containing protein. (441 aa)
	LOC103044237	Inositol polyphosphate-5-phosphatase Ka. (548 aa)
	ENSAMXP00000045325	Chondroadherin-like a. (620 aa)
	ENSAMXP00000045415	PWWP domain-containing protein. (211 aa)
	ENSAMXP00000045469	SH3 and multiple ankyrin repeat domains 1. (1896 aa)
	LOC103046653	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (284 aa)
	LOC111197359	Uncharacterized protein. (492 aa)
	sptan1	Spectrin alpha, non-erythrocytic 1. (2503 aa)
	LOC103046390	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
	ENSAMXP00000046379	TACC_C domain-containing protein. (4832 aa)
	LOC103040240	Stathmin 1b. (220 aa)
	ENSAMXP00000047139	SCA7 domain-containing protein. (446 aa)
	add2	Adducin 2 (beta). (667 aa)
	Capg	Capping protein (actin filament), gelsolin-like b. (359 aa)
	LOC103045760	Inositol polyphosphate-5-phosphatase Kb. (515 aa)
	LOC103021754	Ataxin 7-like 2b. (729 aa)
	ENSAMXP00000049566	Uncharacterized protein. (54 aa)
	Prkn	Parkin RBR E3 ubiquitin protein ligase. (417 aa)
	LOC111196766	Leiomodin 2 (cardiac) b. (608 aa)
	Camsap3	CKK domain-containing protein. (171 aa)
	LOC103030385	Clusterin; Belongs to the clusterin family. (461 aa)
	mkks	McKusick-Kaufman syndrome. (596 aa)
	ENSAMXP00000051168	Thymosin beta 4 X-linked. (58 aa)
	Tmod1	Tropomodulin 1. (334 aa)
	pfdn5	Prefoldin 5. (153 aa)
	LOC103035734	KN motif and ankyrin repeat domains 3. (950 aa)
	ENSAMXP00000053345	MH1 domain-containing protein. (187 aa)
	Kank4	KN motif and ankyrin repeat domains 4. (1181 aa)
	capzb	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (274 aa)
	ENSAMXP00000053941	Supervillin a. (2152 aa)
	pick1	Protein interacting with prkca 1. (411 aa)
	LOC103047712	Spectrin beta chain; Belongs to the spectrin family. (2355 aa)
	ENSAMXP00000054922	Non-specific serine/threonine protein kinase. (612 aa)
	ENSAMXP00000055076	IPPc domain-containing protein. (480 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Add1	W5L261_ASTMX	ENSAMXP00000027529	ENSAMXP00000013923	Adducin 1 (alpha).	Adducin 3 (gamma) a.	0.636
Add1	add2	ENSAMXP00000027529	ENSAMXP00000047829	Adducin 1 (alpha).	Adducin 2 (beta).	0.635
Add1	capzb	ENSAMXP00000027529	ENSAMXP00000053864	Adducin 1 (alpha).	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.480
Apc	LOC103039722	ENSAMXP00000019872	ENSAMXP00000040668	APC regulator of WNT signaling pathway.	Microtubule-associated protein, RP/EB family, member 1a.	0.544
Apc	apc2	ENSAMXP00000019872	ENSAMXP00000019506	APC regulator of WNT signaling pathway.	APC regulator of WNT signaling pathway 2.	0.906
Apc	mapre1	ENSAMXP00000019872	ENSAMXP00000042556	APC regulator of WNT signaling pathway.	Microtubule-associated protein, RP/EB family, member 1b.	0.544
Camsap3	ENSAMXP00000043075	ENSAMXP00000050279	ENSAMXP00000043075	CKK domain-containing protein.	Calponin-homology (CH) domain-containing protein.	0.419
Camsap3	W5L5A1_ASTMX	ENSAMXP00000050279	ENSAMXP00000015013	CKK domain-containing protein.	Calmodulin regulated spectrin-associated protein 1a.	0.754
Capg	ENSAMXP00000031175	ENSAMXP00000048674	ENSAMXP00000031175	Capping protein (actin filament), gelsolin-like b.	Twinfilin actin-binding protein 1b.	0.454
Capg	LOC103022587	ENSAMXP00000048674	ENSAMXP00000037282	Capping protein (actin filament), gelsolin-like b.	Twinfilin actin-binding protein 2a.	0.454
Capg	LOC103023282	ENSAMXP00000048674	ENSAMXP00000007145	Capping protein (actin filament), gelsolin-like b.	Twinfilin actin-binding protein 2b.	0.454
Capg	LOC103042463	ENSAMXP00000048674	ENSAMXP00000038619	Capping protein (actin filament), gelsolin-like b.	Tropomodulin 2.	0.496
Capg	LOC103047464	ENSAMXP00000048674	ENSAMXP00000015044	Capping protein (actin filament), gelsolin-like b.	Twinfilin actin-binding protein 1a.	0.454
ENSAMXP00000027852	ENSAMXP00000032701	ENSAMXP00000027852	ENSAMXP00000032701	Uncharacterized protein.	PH domain-containing protein.	0.861
ENSAMXP00000027852	sptan1	ENSAMXP00000027852	ENSAMXP00000045709	Uncharacterized protein.	Spectrin alpha, non-erythrocytic 1.	0.848
ENSAMXP00000028508	sptan1	ENSAMXP00000028508	ENSAMXP00000045709	Calponin-homology (CH) domain-containing protein.	Spectrin alpha, non-erythrocytic 1.	0.863
ENSAMXP00000031175	Capg	ENSAMXP00000031175	ENSAMXP00000048674	Twinfilin actin-binding protein 1b.	Capping protein (actin filament), gelsolin-like b.	0.454
ENSAMXP00000031175	LOC103033745	ENSAMXP00000031175	ENSAMXP00000040566	Twinfilin actin-binding protein 1b.	Gelsolin a.	0.454
ENSAMXP00000031175	LOC103042463	ENSAMXP00000031175	ENSAMXP00000038619	Twinfilin actin-binding protein 1b.	Tropomodulin 2.	0.429
ENSAMXP00000031175	LOC103046390	ENSAMXP00000031175	ENSAMXP00000045757	Twinfilin actin-binding protein 1b.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.585