32 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111191478	Betacellulin, epidermal growth factor family member. (183 aa)
	LOC103035747	Uncharacterized protein; Belongs to the peptidase C14A family. (290 aa)
	sav1	Salvador family WW domain containing protein 1. (405 aa)
	ENSAMXP00000040228	CARD domain-containing protein. (110 aa)
	pdx1	Pancreatic and duodenal homeobox 1. (236 aa)
	LOC103042559	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
	LOC103033476	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (304 aa)
	LOC103041475	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
	LOC103023682	SIX homeobox 6a. (240 aa)
	capn10	Calpain 10; Belongs to the peptidase C2 family. (648 aa)
	ENSAMXP00000033131	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (475 aa)
	LOC107197257	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (451 aa)
	LOC103035477	SIX homeobox 6b. (242 aa)
	Bmpr2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (191 aa)
	LOC103025318	NK2 homeobox 5. (313 aa)
	angptl4	Angiopoietin-like 4. (451 aa)
	W5LTZ3_ASTMX	ADP-ribosylation factor 6b; Belongs to the small GTPase superfamily. Arf family. (120 aa)
	ARF6	ADP ribosylation factor 6. (116 aa)
	LOC103029060	CD248 molecule, endosialin b. (703 aa)
	tgfbr2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
	E2f1	E2F transcription factor 1. (432 aa)
	LOC103038426	SIX homeobox 7. (258 aa)
	LOC103036066	Uncharacterized protein; Belongs to the peptidase C14A family. (305 aa)
	tmf1	TATA element modulatory factor 1. (1161 aa)
	W5KN49_ASTMX	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (67 aa)
	Rb1	Retinoblastoma 1. (882 aa)
	Bax	BCL2 associated X, apoptosis regulator a. (190 aa)
	LOC103041009	Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
	six3	SIX homeobox 3a. (294 aa)
	LOC103047430	CD248 molecule, endosialin a. (752 aa)
	LOC103035166	SIX homeobox 3b. (289 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bax	ENSAMXP00000040228	ENSAMXP00000005311	ENSAMXP00000040228	BCL2 associated X, apoptosis regulator a.	CARD domain-containing protein.	0.533
Bmpr2	LOC103041475	ENSAMXP00000030317	ENSAMXP00000049576	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.903
E2f1	Rb1	ENSAMXP00000017451	ENSAMXP00000005604	E2F transcription factor 1.	Retinoblastoma 1.	0.999
ENSAMXP00000033131	LOC107197257	ENSAMXP00000033131	ENSAMXP00000032052	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.902
ENSAMXP00000040228	Bax	ENSAMXP00000040228	ENSAMXP00000005311	CARD domain-containing protein.	BCL2 associated X, apoptosis regulator a.	0.533
ENSAMXP00000040228	LOC103033476	ENSAMXP00000040228	ENSAMXP00000046694	CARD domain-containing protein.	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.960
ENSAMXP00000040228	LOC103035747	ENSAMXP00000040228	ENSAMXP00000035326	CARD domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.960
ENSAMXP00000040228	LOC103036066	ENSAMXP00000040228	ENSAMXP00000010539	CARD domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.619
ENSAMXP00000040228	LOC103041009	ENSAMXP00000040228	ENSAMXP00000005247	CARD domain-containing protein.	Tumor necrosis factor b (TNF superfamily, member 2).	0.614
LOC103033476	ENSAMXP00000040228	ENSAMXP00000046694	ENSAMXP00000040228	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	CARD domain-containing protein.	0.960
LOC103033476	LOC103035747	ENSAMXP00000046694	ENSAMXP00000035326	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.902
LOC103035747	ENSAMXP00000040228	ENSAMXP00000035326	ENSAMXP00000040228	Uncharacterized protein; Belongs to the peptidase C14A family.	CARD domain-containing protein.	0.960
LOC103035747	LOC103033476	ENSAMXP00000035326	ENSAMXP00000046694	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.902
LOC103036066	ENSAMXP00000040228	ENSAMXP00000010539	ENSAMXP00000040228	Uncharacterized protein; Belongs to the peptidase C14A family.	CARD domain-containing protein.	0.619
LOC103041009	ENSAMXP00000040228	ENSAMXP00000005247	ENSAMXP00000040228	Tumor necrosis factor b (TNF superfamily, member 2).	CARD domain-containing protein.	0.614
LOC103041009	LOC103042559	ENSAMXP00000005247	ENSAMXP00000043824	Tumor necrosis factor b (TNF superfamily, member 2).	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.481
LOC103041009	tgfbr2	ENSAMXP00000005247	ENSAMXP00000021003	Tumor necrosis factor b (TNF superfamily, member 2).	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.481
LOC103041475	Bmpr2	ENSAMXP00000049576	ENSAMXP00000030317	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.903
LOC103042559	LOC103041009	ENSAMXP00000043824	ENSAMXP00000005247	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Tumor necrosis factor b (TNF superfamily, member 2).	0.481
LOC103042559	tgfbr2	ENSAMXP00000043824	ENSAMXP00000021003	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.902