STRINGSTRING
gadd45a gadd45a LOC103030977 LOC103030977 BCL2 BCL2 Tspo Tspo W5K407_ASTMX W5K407_ASTMX tgfb1 tgfb1 park7 park7 LOC103037777 LOC103037777 coq7 coq7 atg5 atg5 W5KCB4_ASTMX W5KCB4_ASTMX LOC103041009 LOC103041009 LOC103029428 LOC103029428 W5KF46_ASTMX W5KF46_ASTMX nfe2l2 nfe2l2 W5KIS2_ASTMX W5KIS2_ASTMX W5KMZ6_ASTMX W5KMZ6_ASTMX LOC103024607 LOC103024607 romo1 romo1 LOC103042289 LOC103042289 W5L372_ASTMX W5L372_ASTMX Abcb7 Abcb7 ripk1 ripk1 tgfbr2 tgfbr2 f2 f2 pid1 pid1 W5LTC8_ASTMX W5LTC8_ASTMX sirt2 sirt2 apopt1 apopt1 LOC103028302 LOC103028302 LOC103036816 LOC103036816 ENSAMXP00000031620 ENSAMXP00000031620 LOC103041742 LOC103041742 LOC103032641 LOC103032641 LOC103032794 LOC103032794 LOC103043231 LOC103043231 dhfr dhfr LOC103040845 LOC103040845 hace1 hace1 tgfb2 tgfb2 Mpv17l Mpv17l pink1 pink1 ENSAMXP00000041728 ENSAMXP00000041728 LOC103029638 LOC103029638 LOC103042559 LOC103042559 Wisp3 Wisp3 ENSAMXP00000054408 ENSAMXP00000054408 LOC103039548 LOC103039548 LOC103028407 LOC103028407 brca1 brca1 Acod1 Acod1 gch1 gch1 Bco2 Bco2 ENSAMXP00000046020 ENSAMXP00000046020 vdac1 vdac1 Prkn Prkn LOC103039435 LOC103039435 LOC103028223 LOC103028223
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gadd45aGrowth arrest and DNA-damage-inducible, alpha, b. (159 aa)
LOC103030977Zinc finger CCCH-type containing 12A. (608 aa)
BCL2BCL2 apoptosis regulator. (201 aa)
TspoTranslocator protein. (170 aa)
W5K407_ASTMXPhosphoinositide kinase, FYVE finger containing. (1923 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
park7Parkinson protein 7. (189 aa)
LOC103037777Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (528 aa)
coq75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (224 aa)
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
W5KCB4_ASTMXBeta-carotene 15, 15-dioxygenase 2, like. (557 aa)
LOC103041009Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
LOC103029428ATP binding cassette subfamily D member 2. (730 aa)
W5KF46_ASTMXTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (561 aa)
nfe2l2Nuclear factor, erythroid 2-like 2a. (637 aa)
W5KIS2_ASTMXApoptosis antagonizing transcription factor. (535 aa)
W5KMZ6_ASTMXSolute carrier family 30 member 10. (367 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
romo1Reactive oxygen species modulator 1. (79 aa)
LOC103042289Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (186 aa)
W5L372_ASTMXImmunoresponsive gene 1, like. (475 aa)
Abcb7ATP-binding cassette, sub-family B (MDR/TAP), member 7. (748 aa)
ripk1Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (678 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
f2Coagulation factor II (thrombin); Belongs to the peptidase S1 family. (619 aa)
pid1Phosphotyrosine interaction domain containing 1. (221 aa)
W5LTC8_ASTMXCytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (523 aa)
sirt2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (387 aa)
apopt1Cytochrome c oxidase assembly factor 8. (195 aa)
LOC103028302Beta-carotene oxygenase 2a. (592 aa)
LOC103036816Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (526 aa)
ENSAMXP00000031620Si:ch211-120k19.1; Belongs to the peroxisomal membrane protein PXMP2/4 family. (171 aa)
LOC103041742Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (186 aa)
LOC103032641Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (526 aa)
LOC103032794Tumor suppressor 2, mitochondrial calcium regulator b. (111 aa)
LOC103043231GTP cyclohydrolase 2. (241 aa)
dhfrDihydrofolate reductase. (191 aa)
LOC103040845Nuclear factor, erythroid 2-like 2b. (569 aa)
hace1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1. (932 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
Mpv17lUncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (195 aa)
pink1PTEN induced kinase 1. (571 aa)
ENSAMXP00000041728Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily. (351 aa)
LOC103029638Growth arrest and DNA-damage-inducible, alpha, a. (163 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
Wisp3Cellular communication network factor 6. (325 aa)
ENSAMXP00000054408Si:dkey-206d17.12. (289 aa)
LOC103039548BCL2 apoptosis regulator. (218 aa)
LOC103028407Uncharacterized protein. (400 aa)
brca1Uncharacterized protein. (1579 aa)
Acod1Aconitate decarboxylase 1. (521 aa)
gch1GTP cyclohydrolase 1. (267 aa)
Bco2Beta-carotene oxygenase 2b. (565 aa)
ENSAMXP00000046020Uncharacterized protein. (220 aa)
vdac1Voltage-dependent anion channel 1. (283 aa)
PrknParkin RBR E3 ubiquitin protein ligase. (417 aa)
LOC103039435Tumor suppressor 2, mitochondrial calcium regulator a. (111 aa)
LOC103028223Dual oxidase 2. (366 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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