STRINGSTRING
LOC103040845 LOC103040845 LOC103030977 LOC103030977 Tspo Tspo tgfb1 tgfb1 LOC103037777 LOC103037777 W5KF46_ASTMX W5KF46_ASTMX nfe2l2 nfe2l2 LOC103024607 LOC103024607 romo1 romo1 W5L372_ASTMX W5L372_ASTMX tgfbr2 tgfbr2 ENSAMXP00000054408 ENSAMXP00000054408 tgfb2 tgfb2 gadd45a gadd45a LOC103028223 LOC103028223 Acod1 Acod1 LOC103042559 LOC103042559 LOC103029638 LOC103029638 ENSAMXP00000041728 ENSAMXP00000041728 LOC103032641 LOC103032641 LOC103041742 LOC103041742 LOC103036816 LOC103036816 W5LTC8_ASTMX W5LTC8_ASTMX pid1 pid1 f2 f2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103040845Nuclear factor, erythroid 2-like 2b. (569 aa)
LOC103030977Zinc finger CCCH-type containing 12A. (608 aa)
TspoTranslocator protein. (170 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
LOC103037777Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (528 aa)
W5KF46_ASTMXTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (561 aa)
nfe2l2Nuclear factor, erythroid 2-like 2a. (637 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
romo1Reactive oxygen species modulator 1. (79 aa)
W5L372_ASTMXImmunoresponsive gene 1, like. (475 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
ENSAMXP00000054408Si:dkey-206d17.12. (289 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
gadd45aGrowth arrest and DNA-damage-inducible, alpha, b. (159 aa)
LOC103028223Dual oxidase 2. (366 aa)
Acod1Aconitate decarboxylase 1. (521 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
LOC103029638Growth arrest and DNA-damage-inducible, alpha, a. (163 aa)
ENSAMXP00000041728Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily. (351 aa)
LOC103032641Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (526 aa)
LOC103041742Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (186 aa)
LOC103036816Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (526 aa)
W5LTC8_ASTMXCytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (523 aa)
pid1Phosphotyrosine interaction domain containing 1. (221 aa)
f2Coagulation factor II (thrombin); Belongs to the peptidase S1 family. (619 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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