(49 nodes) PAS domain network (Astyanax mexicanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103033873	Hypoxia inducible factor 1 subunit alpha b. (785 aa)
	kcnh5	Potassium voltage-gated channel, subfamily H (eag-related), member 5b. (1019 aa)
	KCNH7	Potassium voltage-gated channel subfamily H member 7. (1188 aa)
	Npas1	Neuronal PAS domain protein 1. (759 aa)
	ENSAMXP00000046638	Uncharacterized protein. (608 aa)
	LOC103031232	Aryl hydrocarbon receptor nuclear translocator-like 1a. (626 aa)
	ENSAMXP00000046054	Phosphodiesterase. (781 aa)
	ENSAMXP00000042136	Potassium voltage-gated channel, subfamily H (eag-related), member 1b. (948 aa)
	LOC103026609	Uncharacterized protein. (1528 aa)
	LOC103044837	Uncharacterized protein. (950 aa)
	LOC103045566	Uncharacterized protein. (904 aa)
	LOC103047410	Aryl hydrocarbon receptor nuclear translocator. (778 aa)
	sim1	SIM bHLH transcription factor 1a. (753 aa)
	hif1a	Hypoxia inducible factor 1 subunit alpha a. (721 aa)
	npas4	Neuronal PAS domain protein 4a. (929 aa)
	ENSAMXP00000033533	Endothelial PAS domain protein 1b. (830 aa)
	SIM2	SIM bHLH transcription factor 2. (758 aa)
	ENSAMXP00000031540	Potassium voltage-gated channel, subfamily H (eag-related), member 4b. (1189 aa)
	LOC103046033	Aryl-hydrocarbon receptor repressor b. (626 aa)
	LOC103025395	Clock circadian regulator b. (838 aa)
	LOC103039499	Uncharacterized protein. (686 aa)
	arntl2	Aryl hydrocarbon receptor nuclear translocator-like 2. (635 aa)
	W5LL98_ASTMX	Aryl-hydrocarbon receptor nuclear translocator 2. (630 aa)
	LOC103027542	Period circadian clock 1a. (1431 aa)
	W5LJT1_ASTMX	Phosphodiesterase. (809 aa)
	LOC103032183	Potassium voltage-gated channel, subfamily H (eag-related), member 5a. (1115 aa)
	LOC103033595	Period circadian clock 1b. (1429 aa)
	LOC103035070	Potassium voltage-gated channel, subfamily H (eag-related), member 3. (756 aa)
	LOC103030770	Aryl hydrocarbon receptor 2. (1035 aa)
	LOC103030458	Aryl hydrocarbon receptor 1b. (938 aa)
	LOC103033764	Uncharacterized protein. (1224 aa)
	LOC103035750	Potassium voltage-gated channel, subfamily H (eag-related), member 6a. (1197 aa)
	Ncoa1	Nuclear receptor coactivator 1. (1346 aa)
	W5KSP2_ASTMX	Potassium voltage-gated channel, subfamily H (eag-related), member 2a. (1115 aa)
	W5KS08_ASTMX	Aryl hydrocarbon receptor nuclear translocator-like 1b. (605 aa)
	LOC103027946	PAS domain-containing protein. (1405 aa)
	LOC103027586	Hypoxia inducible factor 1 subunit alpha, like. (636 aa)
	NPAS3	Neuronal PAS domain protein 3. (857 aa)
	W5KIQ9_ASTMX	Hypoxia inducible factor 1 subunit alpha, like 2. (701 aa)
	W5KHP9_ASTMX	Neuronal PAS domain protein 2. (842 aa)
	W5KHP0_ASTMX	Nuclear receptor coactivator 3. (1496 aa)
	W5KF77_ASTMX	Uncharacterized protein. (864 aa)
	Clock	Clock circadian regulator a. (917 aa)
	per3	Period circadian clock 3. (1257 aa)
	W5K4R8_ASTMX	Potassium voltage-gated channel, subfamily H (eag-related), member 1a. (930 aa)
	LOC103039742	Period circadian clock 2. (1439 aa)
	ncoa2	Nuclear receptor coactivator. (1502 aa)
	kcnh4	Potassium voltage-gated channel, subfamily H (eag-related), member 4a. (1163 aa)
	LOC103036701	Endothelial PAS domain protein 1a. (816 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Clock	ENSAMXP00000033533	ENSAMXP00000005699	ENSAMXP00000033533	Clock circadian regulator a.	Endothelial PAS domain protein 1b.	0.541
Clock	ENSAMXP00000046638	ENSAMXP00000005699	ENSAMXP00000046638	Clock circadian regulator a.	Uncharacterized protein.	0.617
Clock	LOC103027542	ENSAMXP00000005699	ENSAMXP00000020518	Clock circadian regulator a.	Period circadian clock 1a.	0.740
Clock	LOC103027586	ENSAMXP00000005699	ENSAMXP00000008817	Clock circadian regulator a.	Hypoxia inducible factor 1 subunit alpha, like.	0.541
Clock	LOC103027946	ENSAMXP00000005699	ENSAMXP00000009026	Clock circadian regulator a.	PAS domain-containing protein.	0.696
Clock	LOC103030458	ENSAMXP00000005699	ENSAMXP00000014317	Clock circadian regulator a.	Aryl hydrocarbon receptor 1b.	0.617
Clock	LOC103030770	ENSAMXP00000005699	ENSAMXP00000014331	Clock circadian regulator a.	Aryl hydrocarbon receptor 2.	0.617
Clock	LOC103031232	ENSAMXP00000005699	ENSAMXP00000046182	Clock circadian regulator a.	Aryl hydrocarbon receptor nuclear translocator-like 1a.	0.826
Clock	LOC103033595	ENSAMXP00000005699	ENSAMXP00000019300	Clock circadian regulator a.	Period circadian clock 1b.	0.708
Clock	LOC103033873	ENSAMXP00000005699	ENSAMXP00000054066	Clock circadian regulator a.	Hypoxia inducible factor 1 subunit alpha b.	0.541
Clock	LOC103036701	ENSAMXP00000005699	ENSAMXP00000000032	Clock circadian regulator a.	Endothelial PAS domain protein 1a.	0.541
Clock	LOC103039499	ENSAMXP00000005699	ENSAMXP00000022186	Clock circadian regulator a.	Uncharacterized protein.	0.699
Clock	LOC103039742	ENSAMXP00000005699	ENSAMXP00000001488	Clock circadian regulator a.	Period circadian clock 2.	0.745
Clock	LOC103044837	ENSAMXP00000005699	ENSAMXP00000041210	Clock circadian regulator a.	Uncharacterized protein.	0.617
Clock	LOC103045566	ENSAMXP00000005699	ENSAMXP00000039598	Clock circadian regulator a.	Uncharacterized protein.	0.617
Clock	LOC103046033	ENSAMXP00000005699	ENSAMXP00000031143	Clock circadian regulator a.	Aryl-hydrocarbon receptor repressor b.	0.617
Clock	NPAS3	ENSAMXP00000005699	ENSAMXP00000008203	Clock circadian regulator a.	Neuronal PAS domain protein 3.	0.584
Clock	Npas1	ENSAMXP00000005699	ENSAMXP00000047934	Clock circadian regulator a.	Neuronal PAS domain protein 1.	0.584
Clock	SIM2	ENSAMXP00000005699	ENSAMXP00000032634	Clock circadian regulator a.	SIM bHLH transcription factor 2.	0.459
Clock	W5KF77_ASTMX	ENSAMXP00000005699	ENSAMXP00000006238	Clock circadian regulator a.	Uncharacterized protein.	0.699