(12 nodes) Biotin/lipoyl attachment network (Astyanax mexicanus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Predicted Interactions

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protein homology

Your Input:
	LOC103043137	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (171 aa)
	LOC103035953	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (483 aa)
	Pcca	Propionyl-CoA carboxylase subunit alpha. (696 aa)
	mccc1	Methylcrotonoyl-CoA carboxylase 1 (alpha). (711 aa)
	LOC103039075	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (170 aa)
	W5KHJ7_ASTMX	Acetyl-CoA carboxylase beta. (2257 aa)
	dlst	Dihydrolipoamide S-succinyltransferase. (454 aa)
	pdhx	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (504 aa)
	dbt	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (494 aa)
	dlat	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (638 aa)
	ENSAMXP00000046836	Lipoyl-binding domain-containing protein. (299 aa)
	ENSAMXP00000042939	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1105 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000042939	ENSAMXP00000046836	ENSAMXP00000042939	ENSAMXP00000046836	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Lipoyl-binding domain-containing protein.	0.900
ENSAMXP00000042939	Pcca	ENSAMXP00000042939	ENSAMXP00000000700	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Propionyl-CoA carboxylase subunit alpha.	0.636
ENSAMXP00000042939	W5KHJ7_ASTMX	ENSAMXP00000042939	ENSAMXP00000007059	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Acetyl-CoA carboxylase beta.	0.582
ENSAMXP00000042939	dlat	ENSAMXP00000042939	ENSAMXP00000036984	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.867
ENSAMXP00000042939	mccc1	ENSAMXP00000042939	ENSAMXP00000001585	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Methylcrotonoyl-CoA carboxylase 1 (alpha).	0.637
ENSAMXP00000046836	ENSAMXP00000042939	ENSAMXP00000046836	ENSAMXP00000042939	Lipoyl-binding domain-containing protein.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.900
ENSAMXP00000046836	Pcca	ENSAMXP00000046836	ENSAMXP00000000700	Lipoyl-binding domain-containing protein.	Propionyl-CoA carboxylase subunit alpha.	0.962
ENSAMXP00000046836	W5KHJ7_ASTMX	ENSAMXP00000046836	ENSAMXP00000007059	Lipoyl-binding domain-containing protein.	Acetyl-CoA carboxylase beta.	0.582
ENSAMXP00000046836	dlat	ENSAMXP00000046836	ENSAMXP00000036984	Lipoyl-binding domain-containing protein.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.867
ENSAMXP00000046836	mccc1	ENSAMXP00000046836	ENSAMXP00000001585	Lipoyl-binding domain-containing protein.	Methylcrotonoyl-CoA carboxylase 1 (alpha).	0.967
LOC103035953	LOC103039075	ENSAMXP00000038288	ENSAMXP00000003775	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.754
LOC103035953	LOC103043137	ENSAMXP00000038288	ENSAMXP00000044978	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.754
LOC103035953	Pcca	ENSAMXP00000038288	ENSAMXP00000000700	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Propionyl-CoA carboxylase subunit alpha.	0.963
LOC103035953	dbt	ENSAMXP00000038288	ENSAMXP00000018516	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.901
LOC103035953	dlat	ENSAMXP00000038288	ENSAMXP00000036984	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.638
LOC103035953	dlst	ENSAMXP00000038288	ENSAMXP00000014784	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Dihydrolipoamide S-succinyltransferase.	0.712
LOC103035953	mccc1	ENSAMXP00000038288	ENSAMXP00000001585	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Methylcrotonoyl-CoA carboxylase 1 (alpha).	0.649
LOC103035953	pdhx	ENSAMXP00000038288	ENSAMXP00000018120	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.648
LOC103039075	LOC103035953	ENSAMXP00000003775	ENSAMXP00000038288	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.754
LOC103039075	LOC103043137	ENSAMXP00000003775	ENSAMXP00000044978	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.901