(115 nodes) Homeobox domain, metazoa network (Astyanax mexicanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103034899	Distal-less homeobox 2b. (279 aa)
	nkx6-1	NK6 homeobox 1. (326 aa)
	LOC103043023	NK2 homeobox 1. (347 aa)
	W5K3P2_ASTMX	Homeobox domain-containing protein. (152 aa)
	nkx6-2	NK6 homeobox 2. (279 aa)
	LOC103035562	BARX homeobox 1. (232 aa)
	LOC103022020	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (257 aa)
	Hoxa1	Homeobox A1a. (341 aa)
	LOC103029665	Motor neuron and pancreas homeobox 2a. (282 aa)
	tlx2	T cell leukemia homeobox 2. (307 aa)
	LOC103047027	Homeobox D12a. (261 aa)
	hoxd10	Homeobox D11a. (279 aa)
	hoxd10-2	Homeobox D10a. (335 aa)
	hoxd4	Homeobox D4a. (256 aa)
	LOC103045492	Homeobox domain-containing protein. (314 aa)
	hoxc5	Homeobox C5a. (273 aa)
	hoxc4	Homeobox domain-containing protein. (325 aa)
	Gbx2	Gastrulation brain homeobox 2. (336 aa)
	LOC107197447	Posterior neuron-specific homeobox. (197 aa)
	dlx2	Dlx2a. (277 aa)
	tlx1	T cell leukemia homeobox 1. (299 aa)
	hlx	H2.0-like homeo box 1 (Drosophila). (374 aa)
	hoxb4	Homeobox B4a. (244 aa)
	hoxb2	Homeobox B2a. (398 aa)
	mnx1	Motor neuron and pancreas homeobox 1. (270 aa)
	hoxb7	Homeobox B7a. (231 aa)
	LOC103029234	Homeobox domain-containing protein. (346 aa)
	dlx1	Distal-less homeobox 1a. (254 aa)
	LOC103034627	H6 family homeobox 4. (223 aa)
	LOC103040314	Muscle segment homeobox 2b. (227 aa)
	LOC103025318	NK2 homeobox 5. (313 aa)
	hoxb1	Homeobox B1a. (314 aa)
	hoxc6	Homeobox C6a. (233 aa)
	LOC103043634	H6 family homeobox 3a. (328 aa)
	LOC103036631	NK3 homeobox 2. (289 aa)
	nkx2-4	NK2 homeobox 4b. (324 aa)
	LOC103041353	Mesenchyme homeobox 2b. (300 aa)
	LOC111192049	Homeobox B5a. (275 aa)
	LOC103033248	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (263 aa)
	cdx4	Caudal type homeobox 4. (271 aa)
	LOC103023568	Homeobox A4. (246 aa)
	ENSAMXP00000031353	Homeobox domain-containing protein. (282 aa)
	LOC103021536	Homeobox protein engrailed-like. (260 aa)
	ENSAMXP00000033200	Homeobox domain-containing protein. (289 aa)
	LOC103032320	Homeobox C10a. (348 aa)
	gbx1	Gastrulation brain homeobox 1. (322 aa)
	MSX1	Msh homeobox 1. (201 aa)
	LOC103030519	Homeobox B6b. (216 aa)
	barx2	BARX homeobox 2. (292 aa)
	ENSAMXP00000035377	Homeobox domain-containing protein. (269 aa)
	LOC103031159	Homeobox C12a. (277 aa)
	LOC103046901	Homeobox B3a. (416 aa)
	meox1	Mesenchyme homeobox 1. (253 aa)
	LOC103039552	Homeobox domain-containing protein. (268 aa)
	Nkx1-1	NK1 transcription factor related 2-like,b. (340 aa)
	LOC103023883	Homeobox A5a. (271 aa)
	hoxb9	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (249 aa)
	nkx3-1	NK3 homeobox 1. (202 aa)
	LOC103043941	H6 family homeobox 2. (276 aa)
	LOC103029979	Homeobox B5b. (281 aa)
	emx2	Empty spiracles homeobox 2. (261 aa)
	LOC107197780	NK2 homeobox 2b. (224 aa)
	en1	Homeobox protein engrailed-like. (227 aa)
	LOC103047329	Homeobox domain-containing protein. (269 aa)
	hoxc11	Homeobox C11a. (306 aa)
	LOC111191376	Homeobox domain-containing protein. (227 aa)
	LOC103033039	NK1 transcription factor related 2-like,a. (273 aa)
	LOC103045183	Empty spiracles homeobox 1. (231 aa)
	hoxd3	Homeobox D3a. (394 aa)
	DBX2	Developing brain homeobox 2. (256 aa)
	ENSAMXP00000042360	Homeobox B1b. (307 aa)
	ENSAMXP00000042495	Homeobox protein. (256 aa)
	LOC103037925	Muscle segment homeobox 3. (261 aa)
	pdx1	Pancreatic and duodenal homeobox 1. (236 aa)
	LOC103045875	Homeobox B6a. (226 aa)
	LOC103044781	Caudal type homeobox 1 b. (263 aa)
	LOC103035573	Homeobox domain-containing protein. (244 aa)
	bsx	Brain-specific homeobox. (276 aa)
	gsx1	Homeobox domain-containing protein. (273 aa)
	gsx2	GS homeobox 2. (260 aa)
	ENSAMXP00000043856	Homeobox domain-containing protein. (336 aa)
	LOC103037310	Homeobox domain-containing protein. (323 aa)
	nkx2-6	Homeobox domain-containing protein. (294 aa)
	LOC103044850	Homeobox B8a. (245 aa)
	hoxc8	Homeobox C8a. (254 aa)
	LOC103029147	Distal-less homeobox 4b. (231 aa)
	dlx5	Distal-less homeobox 5a. (276 aa)
	nkx6-3	NK6 homeobox 3. (273 aa)
	dlx6	Distal-less homeobox 6a. (247 aa)
	LOC103035191	Homeobox domain-containing protein. (297 aa)
	barhl2	BarH-like homeobox 2. (365 aa)
	LOC103047662	Even-skipped homeobox 1. (397 aa)
	LOC103039812	Homeobox domain-containing protein. (234 aa)
	LOC103022319	Homeobox A11a. (293 aa)
	LOC103042348	H6 family homeobox 3. (275 aa)
	dlx3	Distal-less homeobox 3b. (265 aa)
	hoxc9	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (259 aa)
	LOC103037976	Homeobox protein engrailed-like. (286 aa)
	LOC103032449	Developing brain homeobox 1b. (295 aa)
	EN2	Homeobox protein engrailed-like. (275 aa)
	hoxa3	Homeobox A4a. (416 aa)
	hmx1	H6 family homeobox 1. (254 aa)
	HMX2	H6 family homeobox 2. (171 aa)
	ENSAMXP00000051136	Distal-less homeobox 4a. (225 aa)
	LOC103023202	Msh homeobox 2. (240 aa)
	LOC107197898	Homeobox B8b. (242 aa)
	LOC103043644	Even-skipped-like1. (245 aa)
	nkx2-3	NK2 homeobox 3. (328 aa)
	LOC103035307	NK3 homeobox 3. (252 aa)
	evx2	Even-skipped homeobox 2. (418 aa)
	ENSAMXP00000054660	BarH-like homeobox 1a. (215 aa)
	LOC103022002	Homeobox domain-containing protein. (217 aa)
	LOC103036524	Developing brain homeobox 1a. (264 aa)
	meox2	Mesenchyme homeobox 2a. (291 aa)
	Hoxa2	Homeobox domain-containing protein. (352 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000043856	LOC103022020	ENSAMXP00000043856	ENSAMXP00000005320	Homeobox domain-containing protein.	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	0.878
ENSAMXP00000043856	LOC103029979	ENSAMXP00000043856	ENSAMXP00000037907	Homeobox domain-containing protein.	Homeobox B5b.	0.425
ENSAMXP00000043856	LOC103032320	ENSAMXP00000043856	ENSAMXP00000033864	Homeobox domain-containing protein.	Homeobox C10a.	0.472
ENSAMXP00000043856	LOC111192049	ENSAMXP00000043856	ENSAMXP00000030399	Homeobox domain-containing protein.	Homeobox B5a.	0.425
ENSAMXP00000043856	hoxa3	ENSAMXP00000043856	ENSAMXP00000049876	Homeobox domain-containing protein.	Homeobox A4a.	0.429
ENSAMXP00000043856	hoxb7	ENSAMXP00000043856	ENSAMXP00000027535	Homeobox domain-containing protein.	Homeobox B7a.	0.437
ENSAMXP00000043856	hoxc4	ENSAMXP00000043856	ENSAMXP00000009674	Homeobox domain-containing protein.	Homeobox domain-containing protein.	0.429
ENSAMXP00000043856	hoxd10-2	ENSAMXP00000043856	ENSAMXP00000007157	Homeobox domain-containing protein.	Homeobox D10a.	0.517
Hoxa2	LOC103023883	ENSAMXP00000055089	ENSAMXP00000036595	Homeobox domain-containing protein.	Homeobox A5a.	0.419
Hoxa2	LOC103029979	ENSAMXP00000055089	ENSAMXP00000037907	Homeobox domain-containing protein.	Homeobox B5b.	0.484
Hoxa2	LOC111192049	ENSAMXP00000055089	ENSAMXP00000030399	Homeobox domain-containing protein.	Homeobox B5a.	0.481
Hoxa2	hoxb7	ENSAMXP00000055089	ENSAMXP00000027535	Homeobox domain-containing protein.	Homeobox B7a.	0.403
LOC103022020	ENSAMXP00000043856	ENSAMXP00000005320	ENSAMXP00000043856	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox domain-containing protein.	0.878
LOC103022020	LOC103023568	ENSAMXP00000005320	ENSAMXP00000031110	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox A4.	0.459
LOC103022020	LOC103029979	ENSAMXP00000005320	ENSAMXP00000037907	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox B5b.	0.400
LOC103022020	LOC111192049	ENSAMXP00000005320	ENSAMXP00000030399	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox B5a.	0.400
LOC103022020	hoxa3	ENSAMXP00000005320	ENSAMXP00000049876	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox A4a.	0.461
LOC103022020	hoxc4	ENSAMXP00000005320	ENSAMXP00000009674	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox domain-containing protein.	0.500
LOC103022020	hoxc6	ENSAMXP00000005320	ENSAMXP00000028753	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox C6a.	0.418
LOC103022319	LOC103032320	ENSAMXP00000045695	ENSAMXP00000033864	Homeobox A11a.	Homeobox C10a.	0.413